Ryo Abe

Overview

Best Publications

• CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis.

  Patrick J. Blair;James L. Riley;David M. Harlan;Ryo Abe

  287
  Citations

• Distinct roles for B7-1 (CD-80) and B7-2 (CD-86) in the initiation of experimental allergic encephalomyelitis.

  Michael K. Racke;Dorothy E. Scott;Laura Quigley;Gary S. Gray

  274
  Citations

• ROLE OF B7:CD28/CTLA-4 IN THE INDUCTION OF CHRONIC RELAPSING EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

  P J Perrin;D Scott;L Quigley;P S Albert

  237
  Citations

• Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness.

  D M Harlan;H Hengartner;M L Huang;Y H Kang

  227
  Citations

• Non-CD28 costimulatory molecules present in T cell rafts induce T cell costimulation by enhancing the association of TCR with rafts.

  Yumi Yashiro-Ohtani;Xu-Yu Zhou;Kazuhito Toyo-oka;Xu-Guang Tai

  217
  Citations

• ICOS Costimulation Requires IL-2 and Can Be Prevented by CTLA-4 Engagement

  James L. Riley;Patrick J. Blair;John T. Musser;Ryo Abe

  214
  Citations

• Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma.

  Hideki Makinoshima;Masahiro Takita;Koichi Saruwatari;Shigeki Umemura

  209
  Citations

• Involvement of the programmed death-1/programmed death-1 ligand pathway in CD4+CD25+ regulatory T-cell activity to suppress alloimmune responses

  Yusuke Kitazawa;Masayuki Fujino;Quanxing Wang;Hiromitsu Kimura

  182
  Citations

• TNF-α is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist–deficient mice

  Reiko Horai;Akiko Nakajima;Katsuyoshi Habiro;Motoko Kotani

  178
  Citations

• Swift Development of Protective Effector Functions in Naive CD8 T Cells Against Malaria Liver Stages

  Gen Ichiro Sano;Julius C.R. Hafalla;Alexandre Morrot;Ryo Abe

  159
  Citations

• Preferential expression of the T-cell receptor V β 3 gene by Mls c reactive T cells

  Ryo Abe;Melanie S. Vacchio;Barbara Fox;Richard J. Hodes

  156
  Citations

• Design and synthesis of a luminescent cyclometalated iridium(III) complex having N,N-diethylamino group that stains acidic intracellular organelles and induces cell death by photoirradiation.

  Shinsuke Moromizato;Yosuke Hisamatsu;Toshihiro Suzuki;Yasuki Matsuo

  142
  Citations

• Critical Requirement for the Membrane-Proximal Cytosolic Tyrosine Residue for CD28-Mediated Costimulation In Vivo

  Yohsuke Harada;Miyoko Tokushima;Yasuyo Matsumoto;Shuhei Ogawa

  138
  Citations

• Cytotoxic T Lymphocyte Antigen 4 (Ctla-4) Engagement Delivers an Inhibitory Signal through the Membrane-Proximal Region in the Absence of the Tyrosine Motif in the Cytoplasmic Tail

  C Nakaseko;S Miyatake;T Iida;S Hara

  138
  Citations

• Two waves of memory B-cell generation in the primary immune response

  Ayako Inamine;Yoshimasa Takahashi;Nobue Baba;Kensuke Miyake

  137
  Citations

• Cross-Linking CD21/CD35 or CD19 Increases Both B7-1 and B7-2 Expression on Murine Splenic B Cells

  Kozono Y;Abe R;Kozono H;Kelly Rg

  134
  Citations

• A Single Amino Acid Alteration in Cytoplasmic Domain Determines IL-2 Promoter Activation by Ligation of CD28 but Not Inducible Costimulator (ICOS)

  Yohsuke Harada;Daisuke Ohgai;Ryosuke Watanabe;Kazuhiro Okano

  133
  Citations

• A Role of Suppressor of Cytokine Signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated Interleukin 2 Production

  Akira Matsumoto;Yoh ichi Seki;Ryosuke Watanabe;Katsuhiko Hayashi

  124
  Citations

• Opposing effects of anti-activation-inducible lymphocyte-immunomodulatory molecule/inducible costimulator antibody on the development of acute versus chronic graft-versus-host disease.

  Shu-hei Ogawa;Go Nagamatsu;Masashi Watanabe;Shiho Watanabe

  121
  Citations

• Development of Th1 and not Th2 immune responses in mice lacking IFN-regulatory factor-4.

  Norio Tominaga;Kozo Ohkusu-Tsukada;Heiichiro Udono;Ryo Abe

  120
  Citations