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Immunology

D-Index
75
Citations
18704
World Ranking
1992
National Ranking
976

Overview

Fidel P Zavala is affiliated with Johns Hopkins University in the United States and conducts research primarily in the fields of Medicine and Immunology and Microbiology. Their work spans several subfields, including Public Health, Environmental and Occupational Health, Virology, Immunology, Molecular Biology, and Radiology, Nuclear Medicine and Imaging.

Zavala's research addresses a range of topics, most notably Malaria Research and Control, Mosquito-borne diseases and control, and HIV Research and Treatment. Additional areas of focus include the Complement system in diseases, Monoclonal and Polyclonal Antibodies Research, Invertebrate Immune Response Mechanisms, as well as vaccines and immunoinformatics approaches.

Some of the recent publications authored or co-authored by Zavala include:

  • "CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment" (2021, Cell)
  • "A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver" (2020, Immunity)
  • "Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination" (2020, Science Translational Medicine)
  • "Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum" (2021, Nature Communications)
  • "An epitope-based malaria vaccine targeting the junctional region of circumsporozoite protein" (2021, npj Vaccines)

The most frequent publication venues where Zavala's work appears include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • npj Vaccines
  • PLoS Pathogens
  • Cell Reports
  • Infection and Immunity

Zavala often collaborates with several co-authors, among whom are Yevel Flores-García, C. Richter King, Azza H. Idris, Emily Locke, and Robert A. Seder. The count of collaborations indicates a recurring professional relationship with these researchers.

Best Publications

  • In Vivo Depletion of CD11c+ Dendritic Cells Abrogates Priming of CD8+ T Cells by Exogenous Cell-Associated Antigens

    Steffen Jung;Derya Unutmaz;Phillip Wong;Gen Ichiro Sano

  • Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria

    Pedro Romero;Janet L. Maryanski;Giampietro Corradin;Ruth S. Nussenzweig

  • Quantification of antigen specific CD8+ T cells using an ELISPOT assay

    Yasushi Miyahira;Kenichiro Murata;Dolores Rodriguez;Juan R. Rodriguez

  • Rationale for Development of a Synthetic Vaccine Against Plasmodium falciparum Malaria

    Fidel Zavala;James P. Tam;Michael R. Hollingdale;Allan H. Cochrane

  • Comparative testing of monoclonal antibodies against Plasmodium falciparum sporozoites for ELISA development.

    R. A. Wirtz;F. Zavala;Y. Charoenvit;G. H. Campbell

  • CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment.

    Mauro Di Pilato;Mauro Di Pilato;Raphael Kfuri-Rubens;Raphael Kfuri-Rubens;Jasper N. Pruessmann;Aleksandra J. Ozga

  • Circumsporozoite proteins of malaria parasites contain a single immunodominant region with two or more identical epitopes

    Fidel Zavala;Alan H. Cochrane;Elizabeth H. Nardin;Ruth S. Nussenzweig

  • Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malaria

    Shengqiang Li;Mauricio Rodrigues;Dolores Rodriguez;Juan Ramon Rodriguez

  • CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes

    Sumana Chakravarty;Ian A. Cockburn;Salih Kuk;Michael G. Overstreet

  • DNA cloning of Plasmodium falciparum circumsporozoite gene: amino acid sequence of repetitive epitope.

    Vincenzo Enea;Joan Ellis;Fidel Zavala;David E. Arnot

  • Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses.

    Silvia B. Boscardin;Julius C.R. Hafalla;Revati F. Masilamani;Alice O. Kamphorst

  • The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites

    Kota Arun Kumar;Gen Ichiro Sano;Silvia Boscardin;Ruth S. Nussenzweig

  • IL-4-secreting CD4+ T cells are crucial to the development of CD8+ T-cell responses against malaria liver stages.

    Luzia H. Carvalho;Gen Ichiro Sano;Julius C R Hafalla;Alexandre Morrot

  • A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

    Neville K. Kisalu;Azza H. Idris;Connor Weidle;Yevel Flores-Garcia

  • Detection of malaria liver-stages in mice infected through the bite of a single Anopheles mosquito using a highly sensitive real-time PCR

    Oscar Bruña-Romero;Julius C.R. Hafalla;Gloria González-Aseguinolaza;Gen-ichiro Sano

  • CD8+ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria

    Mauricio M. Rodrigues;Anne Sophie Cordey;Gladys Arreaza;Giampetro Corradin

  • Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria.

    J. P. Tam;P. Clavijo;Yi-An Lu;V. Nussenzweig

  • Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites

    Moriya Tsuji;Denise Mattei;Ruth S. Nussenzweig;Daniel Eichinger

  • Looking under the skin: the first steps in malarial infection and immunity

    Robert Ménard;Joana Tavares;Ian Cockburn;Miles Markus

  • Gamma delta T cells contribute to immunity against the liver stages of malaria in alpha beta T-cell-deficient mice

    Moriya Tsuji;Peter Mombaerts;Peter Mombaerts;Leo Lefrancois;Ruth S. Nussenzweig

Frequent Co-Authors

Ruth S. Nussenzweig
Ruth S. Nussenzweig New York University
Moriya Tsuji
Moriya Tsuji Aaron Diamond AIDS Research Center
Victor Nussenzweig
Victor Nussenzweig New York University
Photini Sinnis
Photini Sinnis Johns Hopkins University
Mariano Esteban
Mariano Esteban Spanish National Research Council
James P. Tam
James P. Tam Nanyang Technological University
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
Mauricio M. Rodrigues
Mauricio M. Rodrigues Federal University of Sao Paulo
Robert A. Seder
Robert A. Seder National Institute of Allergy and Infectious Diseases
Christian F. Ockenhouse
Christian F. Ockenhouse Walter Reed Army Institute of Research

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