World's Best Scientists 2026 revealed!
Stephen L. Hoffman

Stephen L. Hoffman

Award Badge
Microbiology
USA
2026

D-Index & Metrics

Microbiology

D-Index
125
Citations
56453
World Ranking
105
National Ranking
53

Medicine

D-Index
126
Citations
56935
World Ranking
2970
National Ranking
1644

Research.com Recognitions

  • 2026 - Research.com Microbiology in United States Leader Award
  • 2025 - Research.com Microbiology in United States Leader Award
  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2004 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Stephen L. Hoffman is affiliated with Sanaria in the United States. Their research spans multiple fields, including Medicine and Immunology and Microbiology, with a significant focus on Public Health, Environmental and Occupational Health, Immunology, Molecular Biology, Parasitology, and Infectious Diseases.

The scientist's work centers primarily on topics such as Malaria Research and Control, Mosquito-borne diseases and control, the Complement system in diseases, vaccines and immunoinformatics approaches, Parasites and Host Interactions, HIV Research and Treatment, and Immune Cell Function and Interaction.

Frequent publication venues for their work include bioRxiv (Cold Spring Harbor Laboratory), the American Journal of Tropical Medicine and Hygiene, Malaria Journal, The Lancet Infectious Diseases, and Nature Communications.

Notable recent papers by Stephen L. Hoffman are:

  • Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans (2021, Cell Reports)
  • Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response (2020, Cell Host & Microbe)
  • Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity (2021, Nature)
  • Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial (2021, Nature Medicine)
  • Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential (2020, Genome Medicine)

Stephen L. Hoffman has collaborated extensively with various researchers, including B. Kim Lee Sim, Thomas L. Richie, Peter F. Billingsley, Benjamin Mordmüller, and Peter G. Kremsner.

The scientist has been recognized by professional organizations and holds the distinction of being a Fellow of the American Association for the Advancement of Science (AAAS) since 2007. They are also a member of the National Academy of Medicine (NAM) since 2004 and of the Association of American Physicians.

Best Publications

  • Genome sequence of the human malaria parasite Plasmodium falciparum

    Malcolm J. Gardner;Neil Hall;Eula Fung;Owen White

  • The Genome Sequence of the Malaria Mosquito Anopheles gambiae

    Robert A. Holt;G. Mani Subramanian;Aaron Halpern;Granger G. Sutton

  • Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine

    Ruobing Wang;Denise L. Doolan;Thong P. Le;Richard C. Hedstrom

  • Comparative genomics of the neglected human malaria parasite Plasmodium vivax

    Jane M. Carlton;Jane M. Carlton;John H. Adams;Joana C. Silva;Shelby L. Bidwell

  • Protection of Humans against Malaria by Immunization with Radiation-Attenuated Plasmodium falciparum Sporozoites

    Stephen L. Hoffman;Lucy M. L. Goh;Thomas C. Luke;Imogene Schneider

  • Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii

    Jane M. Carlton;Samuel V. Angiuoli;Bernard B. Suh;Taco W. Kooij

  • Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine

    Robert A. Seder;Lee Jah Chang;Mary E. Enama;Kathryn L. Zephir

  • Several Common HLA-DR Types Share Largely Overlapping Peptide Binding Repertoires

    Southwood S;Sidney J;Kondo A;del Guercio Mf

  • Meta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?

    Thomas C. Luke;Edward M. Kilbane;Jeffrey L. Jackson;Stephen L. Hoffman

  • Funding for malaria genome sequencing

    Stephen L. Hoffman;William H. Bancroft;Gottlieb Michael;Stephanie L. James

  • Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.

    Martha M. Sedegah;Richard Hedstrom;Peter Hobart;Stephen L. Hoffman

  • Live attenuated malaria vaccine designed to protect through hepatic CD8+ T cell immunity

    J. E. Epstein;K. Tewari;K. E. Lyke;B. K. L. Sim

  • Chromosome 2 Sequence of the Human Malaria Parasite Plasmodium falciparum

    Malcolm J. Gardner;Hervé Tettelin;Daniel J. Carucci;Leda M. Cummings

  • SAFETY AND EFFICACY OF A RECOMBINANT DNA PLASMODIUM FALCIPARUM SPOROZOITE VACCINE

    W. Ripley Ballou;JamesA. Sherwood;JamesA. Sherwood;FranklinA. Neva;DanielM. Gordon

  • Primaquine Therapy for Malaria

    J. Kevin Baird;Stephen L. Hoffman

  • Diagnosis of malaria by detection of Plasmodium falciparum HRP-2 antigen with a rapid dipstick antigen-capture assay

    C Beadle;G.W Long;P.D McElroy;S.L Hoffman

  • Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

    Benjamin Mordmüller;Güzin Surat;Heimo Lagler;Heimo Lagler;Sumana Chakravarty

  • The Complexity of Protective Immunity Against Liver-Stage Malaria

    Denise L. Doolan;Stephen L. Hoffman

  • Malarial epitopes expressed on the surface of recombinant tobacco mosaic virus.

    Thomas H. Turpen;Stephen J. Reinl;Yupin Charoenvit;Stephen L. Hoffman

  • Protection against malaria at 1 year and immune correlates following PfSPZ vaccination.

    Andrew S Ishizuka;Kirsten E Lyke;Adam DeZure;Andrea A Berry

  • Reduction of mortality in chloramphenicol-treated severe typhoid fever by high-dose dexamethasone.

    Stephen L. Hoffman;Narain H. Punjabi;Swiandy Kumala;M. Asril Moechtar

Frequent Co-Authors

Martha Sedegah
Martha Sedegah Naval Medical Research Center
Denise L. Doolan
Denise L. Doolan Australian Institute of Tropical Health and Medicine
Thomas L. Richie
Thomas L. Richie Naval Medical Research Center
Marcel Tanner
Marcel Tanner Swiss Tropical and Public Health Institute
Peter G. Kremsner
Peter G. Kremsner University of Tübingen
Benjamin Mordmüller
Benjamin Mordmüller Radboud University Medical Center
Robert W. Sauerwein
Robert W. Sauerwein Radboud University
Daniel J. Carucci
Daniel J. Carucci Naval Medical Research Center
Robert A. Seder
Robert A. Seder National Institute of Allergy and Infectious Diseases

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a microbiology degree opens doors to various related fields, many of which you can explore through online education. For those interested in healthcare administration, programs like the online medical billing and coding certificate fast offer a quick pathway to enter the medical industry with valuable coding skills essential for hospital and clinic operations.

If you aim to combine science with patient care, exploring medical degrees online that pay well can guide you toward high-demand professions, including nursing, physician assistant programs, and specialized medical fields that complement microbiology knowledge.

For graduates interested in public health, many online public health masters programs easy to get into provide accessible opportunities to advance your education and impact community health through disease prevention, epidemiology, and health policy—natural progressions for microbiology experts.

Finally, careers like child life specialist merge science and psychology to support young patients in healthcare settings. Understanding how much do child life specialists make helps you evaluate this rewarding path, especially when paired with a background in microbiology and healthcare knowledge.

Best Scientists Citing Stephen L. Hoffman

Trending Scientists

Recently Published Articles