Martha Sedegah mainly investigates Virology, Immunology, Plasmodium yoelii, Immunization and Circumsporozoite protein. Her Virology research integrates issues from Immunity, CD8, Immune system, Antigen and Cytotoxic T cell. Her works in PfSPZ vaccine and Monoclonal antibody are all subjects of inquiry into Immunology.
Martha Sedegah interconnects Molecular biology, Interleukin 12, Interferon gamma and Recombinant DNA in the investigation of issues within Plasmodium yoelii. Her Immunization study frequently draws connections to adjacent fields such as Malaria. Her Circumsporozoite protein course of study focuses on DNA vaccination and Immunogenicity.
Her scientific interests lie mostly in Virology, Immunology, Plasmodium yoelii, Antigen and Malaria. Her studies in Virology integrate themes in fields like Plasmodium falciparum, Malaria vaccine, Circumsporozoite protein, DNA vaccination and Antibody. Her study in the fields of PfSPZ vaccine under the domain of Plasmodium falciparum overlaps with other disciplines such as Transmission.
Her Plasmodium yoelii study combines topics from a wide range of disciplines, such as Heterologous, Interferon gamma, Microbiology, Epitope and Cytotoxic T cell. Her Antigen research is multidisciplinary, incorporating perspectives in Molecular biology and Ex vivo. Her studies examine the connections between Malaria and genetics, as well as such issues in Immunity, with regards to Viral vector.
Her primary areas of investigation include Malaria, Immunology, Virology, Plasmodium falciparum and Antigen. Her Malaria study also includes
Her biological study spans a wide range of topics, including Chloroquine and Immunization. She has researched Antigen in several fields, including Antibody and Cohort. Martha Sedegah combines subjects such as Immune system and Plasmodium yoelii with her study of Antibody.
Martha Sedegah mostly deals with Immunology, Malaria, Plasmodium falciparum, Malaria vaccine and Immunization. Her study in the field of Antigen and T cell is also linked to topics like Transforming growth factor beta. Her research integrates issues of B cell, Seroconversion and Immune system, Immunity in her study of Antigen.
Her Malaria vaccine study integrates concerns from other disciplines, such as Tolerability, Adverse effect, Insect bites and stings and Immunogenicity. Her research in Immunization intersects with topics in Virology, Treatment outcome, Subunit vaccines, Plasmodium and Malaria falciparum. In her work, she performs multidisciplinary research in Virology and Population.
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Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine
Ruobing Wang;Denise L. Doolan;Thong P. Le;Richard C. Hedstrom.
Protection of Humans against Malaria by Immunization with Radiation-Attenuated Plasmodium falciparum Sporozoites
Stephen L. Hoffman;Lucy M. L. Goh;Thomas C. Luke;Imogene Schneider.
The Journal of Infectious Diseases (2002)
Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine
Robert A. Seder;Lee Jah Chang;Mary E. Enama;Kathryn L. Zephir.
Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.
Martha M. Sedegah;Richard Hedstrom;Peter Hobart;Stephen L. Hoffman.
Proceedings of the National Academy of Sciences of the United States of America (1994)
CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites
Walter R. Weiss;Martha Sedegah;Richard L. Beaudoin;Louis H. Miller.
Proceedings of the National Academy of Sciences of the United States of America (1988)
Live attenuated malaria vaccine designed to protect through hepatic CD8+ T cell immunity
J. E. Epstein;K. Tewari;K. E. Lyke;B. K. L. Sim.
Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria.
Stephen L Hoffman;Peter F Billingsley;Eric James;Adam Richman.
Human Vaccines (2010)
Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity.
Denise L. Doolan;Martha Sedegah;Richard C. Hedstrom;Peter Hobart.
Journal of Experimental Medicine (1996)
Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine
Martha Sedegah;Trevor R. Jones;Manjit Kaur;Richard Hedstrom.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers.
Thong P. Le;Kevin M. Coonan;Richard C. Hedstrom;Yupin Charoenvit.
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