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Robert W. Sauerwein

Robert W. Sauerwein

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Microbiology
Netherlands
2022

D-Index & Metrics

Microbiology

D-Index
111
Citations
37789
World Ranking
235
National Ranking
16

Medicine

D-Index
111
Citations
38586
World Ranking
5392
National Ranking
203

Research.com Recognitions

  • 2022 - Research.com Microbiology in Netherlands Leader Award

Overview

Robert W. Sauerwein is affiliated with Radboud University in the Netherlands and has contributed extensively to the fields of Medicine, Immunology, and Microbiology. Their research encompasses a range of topics centered on infectious diseases and immune mechanisms, particularly focusing on malaria and mosquito-borne diseases.

The main fields of study for Sauerwein include Medicine, with 99 publications, and Immunology and Microbiology, with 42 publications. Subfields of their work cover Public Health, Environmental and Occupational Health (70 publications), Immunology (27 publications), Molecular Biology (12 publications), Epidemiology (9 publications), and Parasitology (9 publications).

The primary research topics associated with Sauerwein are:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Invertebrate Immune Response Mechanisms
  • Complement system in diseases
  • HIV Research and Treatment
  • Parasites and Host Interactions
  • Drug Transport and Resistance Mechanisms

Sauerwein has published in various scientific venues, with frequent appearances in:

  • bioRxiv (Cold Spring Harbor Laboratory) - 8 publications
  • SSRN Electronic Journal - 4 publications
  • Immunity - 3 publications
  • Science Translational Medicine - 3 publications
  • Nature Communications - 3 publications

Selected recent papers include:

  • "Trained immunity, tolerance, priming and differentiation: distinct immunological processes," 2020, Nature Immunology
  • "A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver," 2020, Immunity
  • "Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential," 2020, Genome Medicine
  • "A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1," 2020, Science Translational Medicine
  • "CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission research," 2021, Nature Communications

Frequent co-authors collaborating with Sauerwein include:

  • Teun Bousema
  • Geert-Jan van Gemert
  • Marga van de Vegte-Bolmer
  • Annie Yang
  • Matthijs M. Jore

Best Publications

  • Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry

    Edwin Lasonder;Edwin Lasonder;Yasushi Ishihama;Jens S. Andersen;Adriaan M. W. Vermunt

  • Protection against a Malaria Challenge by Sporozoite Inoculation

    Meta Roestenberg;Matthew McCall;Joost Hopman;Jorien Wiersma

  • Hitting Hotspots: Spatial Targeting of Malaria for Control and Elimination

    Teun Bousema;Jamie T. Griffin;Robert W. Sauerwein;David L. Smith

  • Trained immunity, tolerance, priming and differentiation: distinct immunological processes.

    Maziar Divangahi;Peter Aaby;Shabaana A. Khader;Luis B. Barreiro

  • High efficiency transfection of Plasmodium berghei facilitates novel selection procedures.

    Chris J. Janse;Blandine Franke-Fayard;Gunnar R. Mair;Jai Ramesar

  • A novel multiple-stage antimalarial agent that inhibits protein synthesis

    Beatriz Baragaña;Irene Hallyburton;Marcus C. S. Lee;Marcus C. S. Lee;Neil R. Norcross

  • A central role for P48/45 in malaria parasite male gamete fertility.

    Melissa R. van Dijk;Chris J. Janse;Joanne Thompson;Andrew P. Waters

  • Targeting Plasmodium PI(4)K to eliminate malaria

    Case W McNamara;Marcus Cs Lee;Chek Shik Lim;Siau Hoi Lim

  • A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites.

    Olivier Silvie;Jean-François Franetich;Stéphanie Charrin;Markus S. Mueller

  • TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans

    Bart Ferwerda;Matthew B. B. McCall;Santos Alonso;Evangelos J. Giamarellos-Bourboulis

  • Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes.

    Anja T.R. Jensen;Pamela Magistrado;Sarah Sharp;Louise Joergensen

  • Submicroscopic Plasmodium falciparum gametocyte densities frequently result in mosquito infection.

    Petra Schneider;J. Teun Bousema;Louis C. Gouagna;Silas Otieno

  • Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

    Meta Roestenberg;Anne C Teirlinck;Matthew B B McCall;Karina Teelen

  • Identification of hot spots of malaria transmission for targeted malaria control.

    Teun Bousema;Teun Bousema;Chris Drakeley;Samwel Gesase;Ramadhan Hashim

  • Detection of Plasmodium falciparum malaria parasites in vivo by real-time quantitative PCR.

    Cornelus C. Hermsen;Denise S.C. Telgt;Ellen H.P. Linders;Louis A.T.F. van de Locht

  • A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

    Margaret A. Phillips;Julie Lotharius;Kennan Marsh;John White

  • Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells

    Melissa R. van Dijk;Bruno Douradinha;Blandine Franke-Fayard;Volker Heussler

  • Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs

    Teun Bousema;Teun Bousema;Lucy Okell;Lucy Okell;Seif Shekalaghe;Jamie T. Griffin

  • Experimental human challenge infections can accelerate clinical malaria vaccine development

    Robert W. Sauerwein;Meta Roestenberg;Vasee S. Moorthy

  • Protein Export Marks the Early Phase of Gametocytogenesis of the Human Malaria Parasite Plasmodium falciparum

    Francesco Silvestrini;Edwin Lasonder;Anna Olivieri;Grazia Camarda

  • A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

    M. A. Phillips;J. Lotharius;K. Marsh;J. White

Frequent Co-Authors

Teun Bousema
Teun Bousema Radboud University
Geert-Jan van Gemert
Geert-Jan van Gemert Radboud University
Cornelus C. Hermsen
Cornelus C. Hermsen Radboud University
Chris Drakeley
Chris Drakeley London School of Hygiene & Tropical Medicine
Chris J. Janse
Chris J. Janse Leiden University Medical Center
Adrian J. F. Luty
Adrian J. F. Luty Institut de Recherche pour le Développement
Dominique Mazier
Dominique Mazier Sorbonne University
Michael Theisen
Michael Theisen University of Copenhagen
Wijnand Eling
Wijnand Eling Radboud University Medical Center

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