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Microbiology

D-Index
88
Citations
25831
World Ranking
767
National Ranking
46

Overview

Chris J. Janse is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily focuses on infectious disease biology, with a significant concentration in malaria research and control. They have contributed extensively to studies involving parasitology, immunology, and molecular biology.

The scientist's main fields of study include:

  • Medicine
  • Immunology and Microbiology

The subfields that characterize their work are:

  • Public Health, Environmental and Occupational Health
  • Immunology
  • Molecular Biology
  • Parasitology
  • Virology

Their research covers a spectrum of topics such as:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Invertebrate Immune Response Mechanisms
  • Complement system in diseases
  • Parasites and Host Interactions
  • Vaccines and immunoinformatics approaches
  • HIV Research and Treatment

Chris J. Janse has published numerous papers, some recent contributions include:

  • "Artemisinin exposure at the ring or trophozoite stage impacts Plasmodium falciparum sexual conversion differently" (2020) in eLife
  • "A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1" (2020) in Science Translational Medicine
  • "Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice" (2021) in npj Vaccines
  • "Sporozoite immunization: innovative translational science to support the fight against malaria" (2023) in Expert Review of Vaccines
  • "Creation and preclinical evaluation of genetically attenuated malaria parasites arresting growth late in the liver" (2022) in npj Vaccines

Frequent publishing venues for this researcher include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • npj Vaccines
  • Frontiers in Cellular and Infection Microbiology
  • Frontiers in Immunology
  • Cellular Microbiology

Their collaborative network features several frequent coauthors, including:

  • Blandine Franke-Fayard
  • Fiona J. A. Geurten
  • Séverine Chevalley-Maurel
  • Hans Kroeze
  • Surendra Kumar Kolli

Best Publications

  • A Comprehensive Survey of the Plasmodium Life Cycle by Genomic, Transcriptomic, and Proteomic Analyses

    Neil Hall;Marianna Karras;J. Dale Raine;Jane M. Carlton;Jane M. Carlton;Jane M. Carlton

  • Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii

    Jane M. Carlton;Samuel V. Angiuoli;Bernard B. Suh;Taco W. Kooij

  • Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae.

    Stephanie Blandin;Shin-Hong Shiao;Luis F Moita;Chris J Janse

  • High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite Plasmodium berghei

    Chris J Janse;Jai Ramesar;Andrew P Waters

  • A Plasmodium berghei reference line that constitutively expresses GFP at a high level throughout the complete life cycle

    Blandine Franke-Fayard;Holly Trueman;Jai Ramesar;Jacqui Mendoza

  • Regulation of sexual development of Plasmodium by translational repression.

    Gunnar R. Mair;Joanna A. M. Braks;Lindsey S. Garver;Joop C. A. G. Wiegant

  • High efficiency transfection of Plasmodium berghei facilitates novel selection procedures.

    Chris J. Janse;Blandine Franke-Fayard;Gunnar R. Mair;Jai Ramesar

  • A central role for P48/45 in malaria parasite male gamete fertility.

    Melissa R. van Dijk;Chris J. Janse;Joanne Thompson;Andrew P. Waters

  • Proteome Analysis of Separated Male and Female Gametocytes Reveals Novel Sex-Specific Plasmodium Biology

    Shahid M. Khan;Blandine Franke-Fayard;Gunnar R. Mair;Edwin Lasonder;Edwin Lasonder

  • Circumsporozoite protein is required for development of malaria sporozoites in mosquitoes

    Robert Ménard;Ali A. Sultan;Claudio Cortes;Rita Altszuler

  • The role of animal models for research on severe malaria.

    Alister G. Craig;Georges E. Grau;Chris Janse;James W. Kazura

  • Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration

    Blandine Franke-Fayard;Chris J. Janse;Margarida Cunha-Rodrigues;Jai Ramesar

  • The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.

    Min Yu;T. R.Santha Kumar;T. R.Santha Kumar;Louis J. Nkrumah;Alida Coppi

  • Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells

    Melissa R. van Dijk;Bruno Douradinha;Blandine Franke-Fayard;Volker Heussler

  • A comprehensive evaluation of rodent malaria parasite genomes and gene expression

    Thomas D Otto;Ulrike Böhme;Andrew P Jackson;Martin Hunt

  • Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development.

    Gunnar R. Mair;Edwin Lasonder;Lindsey S. Garver;Lindsey S. Garver;Blandine M. D. Franke-Fayard

  • Stable transfection of malaria parasite blood stages

    M. R. van Dijk;A. P. Waters;C. J. Janse

  • Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging.

    Ivo H. J. Ploemen;Miguel Prudêncio;Bruno G. Douradinha;Jai Ramesar

  • Integrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression.

    Edwin Lasonder;Sanna R. Rijpma;Ben C.L. van Schaijk;Wieteke A.M. Hoeijmakers

  • P25 and P28 proteins of the malaria ookinete surface have multiple and partially redundant functions

    Ana M. Tomas;Gabriele Margos;George Dimopoulos;Leo H.M. van Lin

Frequent Co-Authors

Andrew P. Waters
Andrew P. Waters University of Glasgow
Blandine Franke-Fayard
Blandine Franke-Fayard Leiden University Medical Center
Robert W. Sauerwein
Robert W. Sauerwein Radboud University
Geert-Jan van Gemert
Geert-Jan van Gemert Radboud University
Barend Mons
Barend Mons Leiden University Medical Center
Adrian V. S. Hill
Adrian V. S. Hill University of Oxford
Robert E. Sinden
Robert E. Sinden Imperial College London
Alan W. Thomas
Alan W. Thomas Biomedical Primate Research Centre
Volker Heussler
Volker Heussler University of Bern
Maria M. Mota
Maria M. Mota University of Lisbon

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