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Microbiology

D-Index
90
Citations
29704
World Ranking
682
National Ranking
69

Medicine

D-Index
90
Citations
29859
World Ranking
12204
National Ranking
1151

Overview

Anthony A. Holder is affiliated with The Francis Crick Institute in the United Kingdom. Their research primarily focuses on the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Specific subfields of study include Public Health, Environmental and Occupational Health, Molecular Biology, Cell Biology, Immunology, and Virology.

The scientist's recent publications cover various aspects of malaria research and related topics. Some of the notable papers include:

  • Real-time dynamics of Plasmodium NDC80 reveals unusual modes of chromosome segregation during parasite proliferation, 2020, Journal of Cell Science
  • Division and Transmission: Malaria Parasite Development in the Mosquito, 2022, Annual Review of Microbiology
  • A divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of a malaria parasite during gametogony and transmission, 2020, eLife
  • Ubiquitin activation is essential for schizont maturation in Plasmodium falciparum blood-stage development, 2020, PLoS Pathogens
  • Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission, 2020, Cell Reports

The main topics of work for Anthony A. Holder include:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • HIV Research and Treatment
  • Microtubule and mitosis dynamics
  • Drug Transport and Resistance Mechanisms
  • Complement system in diseases
  • Trypanosoma species research and implications

Frequent co-authors collaborating with Anthony A. Holder comprise:

  • Rita Tewari
  • Mohammad Zeeshan
  • Declan Brady
  • David Ferguson
  • Andrew R. Bottrill

Publication venues where Holder has frequently contributed include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Biology
  • eLife
  • Life Science Alliance
  • Malaria Journal

Best Publications

  • A proteomic view of the Plasmodium falciparum life cycle

    Laurence Florens;Michael P. Washburn;J. Dale Raine;Robert M. Anthony

  • Discovery of Gene Function by Expression Profiling of the Malaria Parasite Life Cycle

    Karine G. Le Roch;Yingyao Zhou;Peter L. Blair;Muni Grainger

  • A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.

    M J Blackman;H G Heidrich;S Donachie;J S McBride

  • Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle

    Karine G. Le Roch;Jeffrey R. Johnson;Laurence Florens;Yingyao Zhou

  • Somatic hybrid plants of potato and tomato regenerated from fused protoplasts

    Georg Melchers;Maria D. Sacristán;Anthony A. Holder

  • Immunization against blood-stage rodent malaria using purified parasite antigens.

    Anthony A. Holder;Robert R. Freeman

  • A conserved molecular motor drives cell invasion and gliding motility across malaria life cycle stages and other apicomplexan parasites.

    Jake Baum;Dave Richard;Julie Healer;Melanie Rug

  • Clinical Immunity to Plasmodium falciparum Malaria Is Associated with Serum Antibodies to the 19-kDa C-Terminal Fragment of the Merozoite Surface Antigen, PfMSP-l

    Andréa F. Egan;Joanne Morris;Guy Barnish;Stephen Allen

  • Biosynthesis and processing of a Plasmodium falciparum schizont antigen recognized by immune serum and a monoclonal antibody.

    A A Holder;R R Freeman

  • Antibodies inhibit the protease-mediated processing of a malaria merozoite surface protein.

    Michael J. Blackman;Terry J. Scott-Finnigan;Shafrira Shai;Anthony A. Holder

  • Primary structure of the precursor to the three major surface antigens of Plasmodium falciparum merozoites.

    Anthony A. Holder;Michael J. Lockyer;Karel G. Odink;Jasbir S. Sandhu

  • Naturally acquired cellular and humoral immune responses to the major merozoite surface antigen (PfMSP1) of Plasmodium falciparum are associated with reduced malaria morbidity.

    E. M. Riley;S. J. Allen;J. G. Wheeler;M. J. Blackman;M. J. Blackman

  • A Role for the Protease Falcipain 1 in Host Cell Invasion by the Human Malaria Parasite

    Doron C. Greenbaum;Amos Baruch;Munira Grainger;Zbynek Bozdech

  • Adaptation of the genetically tractable malaria pathogen Plasmodium knowlesi to continuous culture in human erythrocytes

    Robert W. Moon;Joanna M. Hall;Farania Rangkuti;YungShwen Ho

  • Proteolytic processing of thePlasmodium falciparum merozoite surface protein-1 produces a membrane-bound fragment containing two epidermal growth factor-like domains

    Michael J. Blackman;Irene T. Ling;Stephen C. Nicholls;Anthony A. Holder

  • A comprehensive evaluation of rodent malaria parasite genomes and gene expression

    Thomas D Otto;Ulrike Böhme;Andrew P Jackson;Martin Hunt

  • Antibodies that Inhibit Malaria Merozoite Surface Protein–1 Processing and Erythrocyte Invasion Are Blocked by Naturally Acquired Human Antibodies

    José A. Guevara Patiño;Anthony A. Holder;Jana S. McBride;Michael J. Blackman

  • Inducible knockdown of Plasmodium gene expression using the glmS ribozyme.

    Parichat Prommana;Chairat Uthaipibull;Chayaphat Wongsombat;Sumalee Kamchonwongpaisan

  • Secondary processing of the Plasmodium falciparum merozoite surface protein-1 (MSP1) by a calcium-dependent membrane-bound serine protease: shedding of MSP133 as a noncovalently associated complex with other fragments of the MSP1.

    Michael J. Blackman;Anthony A. Holder

  • The precursor to major merozoite surface antigens: structure and role in immunity.

    Anthony A. Holder

Frequent Co-Authors

Rita Tewari
Rita Tewari University of Nottingham
Edward W. Tate
Edward W. Tate Imperial College London
Michael J. Blackman
Michael J. Blackman London School of Hygiene & Tropical Medicine
Robin J. Leatherbarrow
Robin J. Leatherbarrow Imperial College London
Arnab Pain
Arnab Pain King Abdullah University of Science and Technology
Eleanor M. Riley
Eleanor M. Riley University of Edinburgh
David J. P. Ferguson
David J. P. Ferguson University of Oxford
Ralph T. Schwarz
Ralph T. Schwarz Philipp University of Marburg
Karine G. Le Roch
Karine G. Le Roch University of California, Riverside
Gordon Langsley
Gordon Langsley Université Paris Cité

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