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Biology and Biochemistry

D-Index
68
Citations
17407
World Ranking
7757
National Ranking
602

Overview

Julian C. Rayner is affiliated with the University of Cambridge in the United Kingdom. Their research primarily focuses on medical and immunological studies with particular attention to infectious diseases and molecular biology. The main fields of study associated with Rayner's work include Medicine and Immunology and Microbiology, with notable subfields such as Public Health, Environmental and Occupational Health, Immunology, Molecular Biology, Parasitology, and Genetics.

The scientist's main research topics center around Malaria Research and Control, along with broader investigations into mosquito-borne diseases and control. Other significant topics encompass the Complement system in diseases, vector-borne infectious diseases, invertebrate immune response mechanisms, HIV research and treatment, and blood groups and transfusion.

Julian C. Rayner has contributed to the following recent scientific papers:

  • Red blood cell tension protects against severe malaria in the Dantu blood group, 2020, Nature
  • Refining the transcriptome of the human malaria parasite Plasmodium falciparum using amplification-free RNA-seq, 2020, BMC Genomics
  • Design and implementation of multiplexed amplicon sequencing panels to serve genomic epidemiology of infectious disease: A malaria case study, 2022, Molecular Ecology Resources
  • The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite, 2021, Nature Communications
  • Regulators of male and female sexual development are critical for the transmission of a malaria parasite, 2023, Cell Host & Microbe

Their frequent co-authors include:

  • Thomas D. Otto
  • Pietro Cicuta
  • Alison Kemp
  • Viola Introini
  • Manuela Carrasquilla

Julian C. Rayner's work is often published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Wellcome Open Research, Scientific Reports, Nature Communications, and PLoS Neglected Tropical Diseases.

Best Publications

  • Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis

    Min Zhang;Chengqi Wang;Thomas D. Otto;Jenna Oberstaller

  • Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum

    Cécile Crosnier;Leyla Y. Bustamante;S. Josefin Bartholdson;Amy K. Bei

  • Origin of the human malaria parasite Plasmodium falciparum in gorillas

    Weimin Liu;Yingying Li;Gerald H Learn;Rebecca S Rudicell

  • Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

    Magnus Manske;Magnus Manske;Olivo Miotto;Olivo Miotto;Susana Campino;Susana Campino;Sarah Auburn;Sarah Auburn;Sarah Auburn

  • Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

    Olivo Miotto;Jacob Almagro-Garcia;Jacob Almagro-Garcia;Jacob Almagro-Garcia;Magnus Manske;Bronwyn MacInnis

  • Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes

    Ellen Bushell;Ana Rita Gomes;Theo Sanderson;Burcu Anar

  • A novel multiple-stage antimalarial agent that inhibits protein synthesis

    Beatriz Baragaña;Irene Hallyburton;Marcus C. S. Lee;Marcus C. S. Lee;Neil R. Norcross

  • Malaria Vaccines: Recent Advances and New Horizons.

    Simon J. Draper;Brandon K. Sack;C. Richter King;Carolyn M. Nielsen

  • Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes

    Greta E Weiss;Paul R Gilson;Tana Taechalertpaisarn;Wai-Hong Tham

  • Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes.

    Manoj T. Duraisingh;Tony Triglia;Stuart A. Ralph;Julian C. Rayner

  • African origin of the malaria parasite Plasmodium vivax

    Weimin Liu;Yingying Li;Katharina S. Shaw;Gerald H. Learn

  • A Plasmodium falciparum Homologue of Plasmodium vivax Reticulocyte Binding Protein (PvRBP1) Defines a Trypsin-resistant Erythrocyte Invasion Pathway

    Julian C. Rayner;Esmeralda Vargas-Serrato;Curtis S. Huber;Mary R. Galinski

  • The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle.

    Virginia M. Howick;Andrew J. C. Russell;Tallulah Andrews;Haynes Heaton

  • Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites.

    Mathieu Brochet;Mark O. Collins;Terry K. Smith;Eloise Thompson

  • Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum

    Alistair Miles;Zamin Iqbal;Paul Vauterin;Richard Pearson

  • Plasmodium falciparum erythrocyte invasion: combining function with immune evasion.

    Gavin J. Wright;Julian C. Rayner

  • Generation of antigenic diversity in Plasmodium falciparum by structured rearrangement of Var genes during mitosis.

    Antoine Claessens;William L. Hamilton;Mihir Kekre;Thomas D. Otto

  • Two Plasmodium falciparum genes express merozoite proteins that are related to Plasmodium vivax and Plasmodium yoelii adhesive proteins involved in host cell selection and invasion

    Julian C. Rayner;Mary R. Galinski;Paul Ingravallo;John W. Barnwell

  • A Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle

    Katarzyna Modrzynska;Claudia Pfander;Lia Chappell;Lu Yu

  • Evolution of human-chimpanzee differences in malaria susceptibility: Relationship to human genetic loss of N-glycolylneuraminic acid

    Maria J. Martin;Julian C. Rayner;Pascal Gagneux;John W. Barnwell

Frequent Co-Authors

Dominic P. Kwiatkowski
Dominic P. Kwiatkowski University of Oxford
Oliver Billker
Oliver Billker Umeå University
Thomas D. Otto
Thomas D. Otto University of Glasgow
Gavin J. Wright
Gavin J. Wright Wellcome Sanger Institute
Beatrice H. Hahn
Beatrice H. Hahn University of Pennsylvania
Paul M. Sharp
Paul M. Sharp University of Edinburgh
Rick M. Fairhurst
Rick M. Fairhurst AstraZeneca (United Kingdom)
Jyoti S. Choudhary
Jyoti S. Choudhary Institute of Cancer Research
David J. Conway
David J. Conway London School of Hygiene & Tropical Medicine
Matthew Berriman
Matthew Berriman University of Glasgow

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