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Microbiology

D-Index
66
Citations
21812
World Ranking
2355
National Ranking
201

Overview

Rick M. Fairhurst is affiliated with AstraZeneca in the United Kingdom. Their research primarily falls within the field of Medicine, with significant contributions to Public Health, Environmental and Occupational Health, Parasitology, Pulmonary and Respiratory Medicine, Oncology, and Genetics.

The scientist's work focuses extensively on malaria research and related infectious diseases. Key topics addressed in their publications include:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Vector-borne infectious diseases
  • Hemoglobinopathies and Related Disorders
  • Computational Drug Discovery Methods
  • Drug-Induced Hepatotoxicity and Protection
  • Parasites and Host Interactions

Recent publications by Rick M. Fairhurst demonstrate involvement in clinical trials, genomic studies, and metabolic research on Plasmodium falciparum. Notable papers include:

  • Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial, 2020, The Lancet
  • An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples, 2021, Wellcome Open Research
  • Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival, 2021, Nature Communications
  • Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples, 2023, Wellcome Open Research
  • Genetic surveillance in the Greater Mekong subregion and South Asia to support malaria control and elimination, 2021, eLife

Their frequent co-authors reflect collaborations with researchers active in malaria and infectious disease research. These include:

  • Chanaki Amaratunga
  • Arjen M. Dondorp
  • Dominic Kwiatkowski
  • Caterina Fanello
  • Elizabeth A. Ashley

Rick M. Fairhurst's publications have appeared repeatedly in venues such as Wellcome Open Research, bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Journal of Clinical Oncology, and Malaria Journal, indicating engagement with both preprint and peer-reviewed platforms relevant to clinical and genomic research.

Best Publications

  • Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

    Ashley Ea;Dhorda M;Fairhurst Rm;Amaratunga C

  • A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

    Frédéric Ariey;Benoit Witkowski;Chanaki Amaratunga;Johann Beghain

  • K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

    Judith Straimer;Nina F. Gnädig;Benoit Witkowski;Chanaki Amaratunga

  • Genetic architecture of artemisinin-resistant Plasmodium falciparum.

    O Miotto;R Amato;E A Ashley;B MacInnis

  • Novel phenotypic assays for the detection of artemisinin- resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies

    Benoit Witkowski;Chanaki Amaratunga;Nimol Khim;Sokunthea Sreng

  • Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

    Magnus Manske;Magnus Manske;Olivo Miotto;Olivo Miotto;Susana Campino;Susana Campino;Sarah Auburn;Sarah Auburn;Sarah Auburn

  • Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

    Olivo Miotto;Jacob Almagro-Garcia;Jacob Almagro-Garcia;Jacob Almagro-Garcia;Magnus Manske;Bronwyn MacInnis

  • Dihydroartemisinin–piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study

    Chanaki Amaratunga;Pharath Lim;Seila Suon;Sokunthea Sreng

  • Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

    Sachel Mok;Elizabeth A. Ashley;Elizabeth A. Ashley;Pedro E. Ferreira;Lei Zhu

  • Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study

    Rob W van der Pluijm;Rob W van der Pluijm;Mallika Imwong;Nguyen Hoang Chau;Nhu Thi Hoa

  • Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study

    Chanaki Amaratunga;Sokunthea Sreng;Seila Suon;Erika S. Phelps

  • Genetic markers associated with dihydroartemisinin-piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype-phenotype association study.

    Roberto Amato;Roberto Amato;Pharath Lim;Olivo Miotto;Olivo Miotto;Olivo Miotto;Chanaki Amaratunga

  • Haemoglobinopathies and the clinical epidemiology of malaria: a systematic review and meta-analysis

    Steve M Taylor;Steve M Taylor;Christian M Parobek;Rick M Fairhurst

  • Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments : a WWARN individual patient data meta-analysis

    Chanaki Amaratunga;Voahangy Hanitriniaina Andrianaranjaka;Elizabeth Ashley;Delia Bethell

  • Artemisinin-Resistant Plasmodium falciparum Malaria

    Rick M. Fairhurst;Arjen M. Dondorp

  • The Threat of Artemisinin-Resistant Malaria

    Arjen M. Dondorp;Rick M. Fairhurst;Laurence Slutsker;John R. MacArthur

  • X-linked G6PD deficiency protects hemizygous males but not heterozygous females against severe malaria.

    Aldiouma Guindo;Rick M Fairhurst;Ogobara K Doumbo;Thomas E Wellems

  • Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study

    William L Hamilton;William L Hamilton;Roberto Amato;Roberto Amato;Rob W van der Pluijm;Rob W van der Pluijm;Christopher G Jacob

  • Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin

    Rushina Cholera;Nathaniel J. Brittain;Mark R. Gillrie;Tatiana M. Lopera-Mesa

  • Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.

    Rob W van der Pluijm;Rob W van der Pluijm;Rob W van der Pluijm;Rupam Tripura;Rupam Tripura;Richard M Hoglund;Richard M Hoglund;Aung Pyae Phyo

  • Abnormal display of PfEMP-1 on erythrocytes carrying haemoglobin C may protect against malaria

    Rick M Fairhurst;Dror I Baruch;Nathaniel J Brittain;Graciela R Ostera

Frequent Co-Authors

Olivo Miotto
Olivo Miotto Mahidol University
Arjen M. Dondorp
Arjen M. Dondorp Mahidol Oxford Tropical Medicine Research Unit
Dominic P. Kwiatkowski
Dominic P. Kwiatkowski University of Oxford
Nicholas J. White
Nicholas J. White Mahidol University
François Nosten
François Nosten MORU Mahidol Oxford Tropical Medicine Research Unit
Elizabeth A. Ashley
Elizabeth A. Ashley University of Oxford
Nicholas P. J. Day
Nicholas P. J. Day University of Oxford
Thomas E. Wellems
Thomas E. Wellems National Institutes of Health
Carole A. Long
Carole A. Long National Institute of Allergy and Infectious Diseases
Paul N. Newton
Paul N. Newton University of Oxford

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