His primary areas of investigation include Alzheimer's disease, Cerebrospinal fluid, Pathology, Dementia and Internal medicine. His Alzheimer's disease study combines topics from a wide range of disciplines, such as Apolipoprotein E and Gerontology. Juan Fortea combines subjects such as Neurodegeneration, Disease, Pathophysiology, Biomarker and Neurology with his study of Cerebrospinal fluid.
His biological study spans a wide range of topics, including Precuneus and Neuroimaging. Frontotemporal dementia is the focus of his Dementia research. His work deals with themes such as Oncology and Cardiology, which intersect with Internal medicine.
Juan Fortea mostly deals with Disease, Cerebrospinal fluid, Dementia, Pathology and Internal medicine. He interconnects Down syndrome, Neuroscience and Bioinformatics in the investigation of issues within Disease. His research on Cerebrospinal fluid also deals with topics like
His work on Cognitive decline as part of general Dementia research is frequently linked to Genetic association, thereby connecting diverse disciplines of science. The concepts of his Pathology study are interwoven with issues in Inflammation and Magnetic resonance imaging. His Alzheimer's disease course of study focuses on Minor allele frequency and Case-control study.
Juan Fortea focuses on Down syndrome, Disease, Neuroscience, Neuroimaging and Cerebrospinal fluid. His Down syndrome research is multidisciplinary, incorporating elements of Life expectancy, Pediatrics and Cohort, Pathology. His research integrates issues of Clinical psychology and Bioinformatics in his study of Disease.
He has researched Neuroimaging in several fields, including Alzheimer's disease, Disease progression, Magnetic resonance imaging and In vivo. His Cerebrospinal fluid research is included under the broader classification of Internal medicine. His Dementia study combines topics in areas such as Cognitive test and Amyloid.
Juan Fortea mainly investigates Dementia, Disease, Cerebrospinal fluid, Internal medicine and Down syndrome. The various areas that he examines in his Dementia study include Genetic architecture, Life expectancy, DNA sequencing and Amyloid. His studies deal with areas such as Gerontology and Bioinformatics as well as Disease.
His Cerebrospinal fluid study integrates concerns from other disciplines, such as Amyloid beta, Cholinergic, Degeneration, Nucleus basalis and Alzheimer's disease. His work is dedicated to discovering how Internal medicine, Gastroenterology are connected with Asymptomatic and other disciplines. His study looks at the relationship between Down syndrome and fields such as Biomarker, as well as how they intersect with chemical problems.
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TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
Gernot Kleinberger;Yoshinori Yamanishi;Marc Suárez-Calvet;Eva Czirr.
Science Translational Medicine (2014)
Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.
Rik Ossenkoppele;Willemijn J Jansen;Gil D Rabinovici;Dirk L Knol.
JAMA (2015)
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez.
Nature Genetics (2017)
sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers
Marc Suárez-Calvet;Marc Suárez-Calvet;Gernot Kleinberger;Miguel Ángel Araque Caballero;Matthias Brendel.
Embo Molecular Medicine (2016)
Amyloid precursor protein metabolism and inflammation markers in preclinical Alzheimer disease.
Daniel Alcolea;Pablo Martínez-Lage;Pascual Sánchez-Juan;Javier Olazarán.
Neurology (2015)
Increased Cortical Thickness and Caudate Volume Precede Atrophy in PSEN1 Mutation Carriers
Juan Fortea;Roser Sala-Llonch;David Bartrés-Faz;Beatriz Bosch.
Journal of Alzheimer's Disease (2010)
Relationship between β-Secretase, inflammation and core cerebrospinal fluid biomarkers for Alzheimer's disease
Daniel Alcolea;María Carmona-Iragui;Marc Suárez-Calvet;M Belén Sánchez-Saudinós.
Journal of Alzheimer's Disease (2014)
Plasma and CSF biomarkers for the diagnosis of Alzheimer's disease in adults with Down syndrome: a cross-sectional study
Juan Fortea;María Carmona-Iragui;Bessy Benejam;Susana Fernández.
Lancet Neurology (2018)
Cognitively preserved subjects with transitional cerebrospinal fluid ß-amyloid 1-42 values have thicker cortex in Alzheimer's disease vulnerable areas.
Juan Fortea;Roser Sala-Llonch;David Bartrés-Faz;Albert Lladó.
Biological Psychiatry (2011)
Characterization of the repeat expansion size in C9orf72 in amyotrophic lateral sclerosis and frontotemporal dementia
Oriol Dols-Icardo;Alberto García-Redondo;Ricard Rojas-García;Raquel Sánchez-Valle.
Human Molecular Genetics (2014)
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