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Peter Paul De Deyn

Peter Paul De Deyn

D-Index & Metrics

Medicine

D-Index
122
Citations
65273
World Ranking
3432
National Ranking
34

Overview

Peter Paul De Deyn is affiliated with the University of Antwerp in Belgium and has a research focus primarily centered on medicine and neuroscience. Their work spans multiple subfields including physiology, neurology, psychiatry and mental health, molecular biology, and cognitive neuroscience.

The main topics covered in their research include:

  • Alzheimer's disease research and treatments
  • Dementia and cognitive impairment research
  • Tryptophan and brain disorders
  • Functional brain connectivity studies
  • Neuroinflammation and neurodegeneration mechanisms
  • Neuroscience and neuropharmacology research
  • Down syndrome and intellectual disability research

Peter Paul De Deyn has published extensively in several scientific journals, with frequent publications in:

  • Alzheimer's & Dementia
  • Journal of Alzheimer's Disease
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurobiology of Aging
  • NeuroImage Clinical

Recent papers authored or co-authored by Peter Paul De Deyn include:

  • Donanemab in Early Symptomatic Alzheimer Disease, 2023, JAMA
  • Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease, 2021, Acta Neuropathologica
  • Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer's disease: a phase 1b, randomized, placebo-controlled trial, 2023, Nature Medicine
  • Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers, 2022, Acta Neuropathologica
  • New insights on the genetic etiology of Alzheimer's and related dementia, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Collaborations are a notable aspect of their research activity, with frequent co-authors including:

  • Yannick Vermeiren
  • Debby Van Dam
  • Sebastiaan Engelborghs
  • Christine Van Broeckhoven
  • Anne Sieben

Best Publications

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

  • Applications of the Morris water maze in the study of learning and memory.

    Rudi D’Hooge;Peter P De Deyn

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Review on uremic toxins: Classification, concentration, and interindividual variability

    Raymond Vanholder;Rita De Smet;Griet Glorieux;Angel Argilés

  • Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

    Marc Cruts;Ilse Gijselinck;Julie van der Zee;Sebastiaan Engelborghs

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Fmr1 knockout mice: A model to study fragile X mental retardation

    Cathy E. Bakker;Coleta Verheij;Rob Willemsen

  • A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study.

    Ilse Gijselinck;Tim Van Langenhove;Julie van der Zee;Kristel Sleegers

  • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

    Günter U. Höglinger;Nadine M. Melhem;Dennis W. Dickson;Patrick M A Sleiman

  • Diagnosis-Independent Alzheimer Disease Biomarker Signature in Cognitively Normal Elderly People

    Geert De Meyer;Fred Shapiro;Hugo Vanderstichele;Eugeen Vanmechelen

  • Neuropsychiatric syndromes in dementia: Results from the European Alzheimer disease Consortium: Part I

    Pauline Aalten;Frans R.J. Verhey;Marina Boziki;Roger Bullock

  • A Multicenter Study of Glucocerebrosidase Mutations in Dementia With Lewy Bodies

    Michael A. Nalls;Raquel Duran;Grisel Lopez;Marzena Kurzawa-Akanbi

  • Rat C6 glioma as experimental model system for the study of glioblastoma growth and invasion

    Bert Grobben;Peter Paul De Deyn;Herman Slegers

  • The lateralized linguistic cerebellum: A review and a new hypothesis

    Peter Marien;Sebastiaan Engelborghs;Franco Fabbro;Peter P. De Deyn

  • Cerebellar neurocognition: insights into the bottom of the brain.

    Hanne Baillieux;Hyo Jung De Smet;Philippe Paquier;Philippe Paquier;Peter Paul De Deyn

  • Decreased expression of the GABAA receptor in fragile X syndrome.

    Charlotte D'Hulst;Natalie De Geest;Simon P. Reeve;Debby Van Dam

  • Age-dependent cognitive decline in the APP23 model precedes amyloid deposition.

    Debby Van Dam;Rudi D'Hooge;Matthias Staufenbiel;Chris Van Ginneken

  • Effects of rivastigmine in patients with and without visual hallucinations in dementia associated with Parkinson's disease

    David Burn;Murat Emre;Ian McKeith;Peter Paul De Deyn

  • Tinzaparin in acute ischaemic stroke (TAIST): a randomised aspirin-controlled trial.

    Philip Mw Bath;Ewa Lindenstrom;Gudrun Boysen;Peter De Deyn

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimertextquotesingles disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

Frequent Co-Authors

Sebastiaan Engelborghs
Sebastiaan Engelborghs University of Antwerp
Debby Van Dam
Debby Van Dam University of Antwerp
Christine Van Broeckhoven
Christine Van Broeckhoven University of Antwerp
Peter Mariën
Peter Mariën Vrije Universiteit Brussel
Kristel Sleegers
Kristel Sleegers University of Antwerp
Patrick Cras
Patrick Cras University of Antwerp
Marc Cruts
Marc Cruts University of Antwerp
Rudi D'Hooge
Rudi D'Hooge KU Leuven
Rudi Dierckx
Rudi Dierckx University Medical Center Groningen

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