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Neuroscience

D-Index
45
Citations
8174
World Ranking
6907
National Ranking
85

Overview

Debby Van Dam is affiliated with the University of Antwerp in Belgium and has a research focus rooted mainly in medicine and neuroscience. Their scholarly output includes extensive work in subfields such as physiology, neurology, molecular biology, biological psychiatry, and cardiology and cardiovascular medicine. The main topics covered by their research span Alzheimer's disease research and treatments, neuroinflammation and neurodegeneration mechanisms, tryptophan and brain disorders, mitochondrial function and pathology, neuroscience and neuropharmacology research, stress responses and cortisol, as well as dementia and cognitive impairment research.

Their publication record includes contributions to several frequent venues, reflecting a broad engagement with the academic community. These venues include:

  • Alzheimer's & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Journal of Alzheimer's Disease
  • International Journal of Molecular Sciences

Among their recent papers, notable works include:

  • "Age-related cognitive decline in spatial learning and memory of C57BL/6J mice" (2021) published in Behavioural Brain Research
  • "Accumulation of Ambient Black Carbon Particles Within Key Memory-Related Brain Regions" (2024) published in JAMA Network Open
  • "5-HT7 receptors in Alzheimer's disease" (2021) published in Neurochemistry International
  • "PapRIV, a BV-2 microglial cell activating quorum sensing peptide" (2021) published in Scientific Reports
  • "Inflammation, Nitro-Oxidative Stress, Impaired Autophagy, and Insulin Resistance as a Mechanistic Convergence Between Arterial Stiffness and Alzheimer's Disease" (2021) published in Frontiers in Molecular Biosciences

Debby Van Dam has collaborated frequently with several co-authors, including:

  • Peter Paul De Deyn
  • Yannick Vermeiren
  • Jhana O. Hendrickx
  • Elke Calus
  • Guido R.Y. De Meyer

The scope of Van Dam's work demonstrates a consistent involvement in exploring the molecular and physiological underpinnings of neurodegenerative diseases and associated cognitive impairments. Their research contributions span experimental approaches in laboratory and clinical neuroscience, linking biochemical mechanisms to disease pathology and potential therapeutic targets. This profile reflects ongoing academic activity focused primarily on neurobiology and related medical sciences.

Best Publications

  • Decreased expression of the GABAA receptor in fragile X syndrome.

    Charlotte D'Hulst;Natalie De Geest;Simon P. Reeve;Debby Van Dam

  • Age-dependent cognitive decline in the APP23 model precedes amyloid deposition.

    Debby Van Dam;Rudi D'Hooge;Matthias Staufenbiel;Chris Van Ginneken

  • Animal models in the drug discovery pipeline for Alzheimer's disease.

    Debby Van Dam;Peter Paul De Deyn

  • PTZ-induced seizures in mice require a revised Racine scale.

    Jan Van Erum;Debby Van Dam;Peter Paul De Deyn

  • Drug discovery in dementia: the role of rodent models

    Debby Van Dam;Peter Paul De Deyn

  • Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease.

    Eloise Hudry;Debby Van Dam;Wim Kulik;Peter P De Deyn

  • Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease

    Zhuoran Yin;Divya Raj;Nasrin Saiepour;Debby Van Dam

  • Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain

    Divya Raj;Zhuoran Yin;Marjolein Breur;Janine Doorduin

  • Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model

    Debby Van Dam;Dorothee Abramowski;Matthias Staufenbiel;Peter Paul De Deyn

  • Spatial learning, contextual fear conditioning and conditioned emotional response in Fmr1 knockout mice

    Debby Van Dam;Rudi D'Hooge;Ehud Hauben;Edwin Reyniers

  • Cognitive decline, neuromotor and behavioural disturbances in a mouse model for fragile-X-associated tremor/ataxia syndrome (FXTAS)

    Debby Van Dam;Vanessa Errijgers;R. Frank Kooy;Rob Willemsen

  • Cellular ageing, increased mortality and FTLD-TDP-associated neuropathology in progranulin knockout mice.

    Hans Wils;Gernot Kleinberger;Sandra Pereson;Jonathan Janssens

  • A new glaucoma hypothesis: a role of glymphatic system dysfunction

    Peter Wostyn;Debby Van Dam;Kurt Audenaert;Hanspeter Esriel Killer

  • Pharmacological treatment of fragile X syndrome with GABAergic drugs in a knockout mouse model.

    Inge Heulens;Charlotte D'Hulst;Debby Van Dam;Peter P. De Deyn

  • Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease.

    Anneleen Schallier;Ilse Julia Smolders;Debby Van Dam;Ellen Loyens

  • Intracerebral adeno-associated virus-mediated gene transfer in rapidly progressive forms of metachromatic leukodystrophy

    Caroline Sevin;Abdellatif Benraiss;Debby Van Dam;Delphine Bonnin

  • Sleep and Alzheimer's disease : A pivotal role for the suprachiasmatic nucleus

    Jan Van Erum;Debby Van Dam;Debby Van Dam;Peter Paul De Deyn;Peter Paul De Deyn

  • Altered circadian locomotor activity in APP23 mice: a model for BPSD disturbances

    Ellen Vloeberghs;Debby Van Dam;Sebastiaan Engelborghs;Guy Nagels

  • Effect of Morris water maze diameter on visual-spatial learning in different mouse strains.

    Debby Van Dam;Guy Lenders;Peter Paul De Deyn

  • Cognitive evaluation of disease-modifying efficacy of galantamine and memantine in the APP23 model.

    Debby Van Dam;Peter Paul De Deyn

Frequent Co-Authors

Matthias Staufenbiel
Matthias Staufenbiel University of Tübingen
Rudi D'Hooge
Rudi D'Hooge KU Leuven
R. Frank Kooy
R. Frank Kooy University of Antwerp
Bart J. L. Eggen
Bart J. L. Eggen University Medical Center Groningen
Annemie Van der Linden
Annemie Van der Linden University of Antwerp
Elly M. Hol
Elly M. Hol Utrecht University
Ilse Smolders
Ilse Smolders Vrije Universiteit Brussel
Erik Boddeke
Erik Boddeke University Medical Center Groningen
Marleen Verhoye
Marleen Verhoye University of Antwerp
Ben A. Oostra
Ben A. Oostra Erasmus University Rotterdam

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