Debby Van Dam focuses on Neuroscience, Internal medicine, Endocrinology, Dementia and Pharmacology. Her research in Neuroscience intersects with topics in Disease and Clinical significance. Her Internal medicine research is multidisciplinary, relying on both Gliosis and Protein subunit.
The study incorporates disciplines such as Receptor, Molecular biology, Presenilin, Regulation of gene expression and Amyloid in addition to Endocrinology. Her work carried out in the field of Dementia brings together such families of science as Alzheimer's disease, Physical therapy, Central nervous system disease and Geriatrics. Her research on Pharmacology also deals with topics like
Her primary areas of investigation include Neuroscience, Internal medicine, Disease, Dementia and Endocrinology. Her Neuroscience research incorporates elements of Genetically modified mouse and Tauopathy. Her research brings together the fields of Cardiology and Internal medicine.
She interconnects Glymphatic system, Glaucoma and Drug discovery in the investigation of issues within Disease. She has researched Dementia in several fields, including Biomarker and Down syndrome, Psychiatry, Psychosis. Her Alzheimer's disease research incorporates themes from Analysis of variance, Pathogenesis, Late life depression and Degenerative disease.
Her primary scientific interests are in Disease, Neuroscience, Electroencephalography, Dementia and Computational biology. Her work deals with themes such as Oxidative stress, Bioinformatics and Risk factor, which intersect with Disease. Her studies in Neuroscience integrate themes in fields like Neuroinflammation and Tauopathy.
Her Electroencephalography study combines topics from a wide range of disciplines, such as Sleep in non-human animals, Cognitive decline, Audiology and Epilepsy. Her Dementia research includes elements of Epidemiology and Clinical psychology. The concepts of her Computational biology study are interwoven with issues in Reference genes, Transcriptome, Rodent model, Gene and Drug discovery.
Her scientific interests lie mostly in Electroencephalography, Epilepsy, Disease, Dementia and Neuroscience. Her studies deal with areas such as Sleep in non-human animals and Audiology as well as Electroencephalography. Her Sleep in non-human animals study integrates concerns from other disciplines, such as Water maze and Cognitive decline.
Her work focuses on many connections between Audiology and other disciplines, such as Insomnia, that overlap with her field of interest in Morris water navigation task. Debby Van Dam combines subjects such as Genetically modified mouse, Convulsant and Tauopathy with her study of Epilepsy. Her Disease study incorporates themes from Neurotransmitter systems and Circadian rhythm.
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Decreased expression of the GABAA receptor in fragile X syndrome.
Charlotte D'Hulst;Natalie De Geest;Simon P. Reeve;Debby Van Dam.
Brain Research (2006)
Age-dependent cognitive decline in the APP23 model precedes amyloid deposition.
Debby Van Dam;Rudi D'Hooge;Matthias Staufenbiel;Chris Van Ginneken.
European Journal of Neuroscience (2003)
Drug discovery in dementia: the role of rodent models
Debby Van Dam;Peter Paul De Deyn.
Nature Reviews Drug Discovery (2006)
Animal models in the drug discovery pipeline for Alzheimer's disease.
Debby Van Dam;Peter Paul De Deyn.
British Journal of Pharmacology (2011)
Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease.
Eloise Hudry;Debby Van Dam;Wim Kulik;Peter P De Deyn.
Molecular Therapy (2010)
Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model
Debby Van Dam;Dorothee Abramowski;Matthias Staufenbiel;Peter Paul De Deyn.
Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease
Zhuoran Yin;Divya Raj;Nasrin Saiepour;Debby Van Dam.
Neurobiology of Aging (2017)
Cognitive decline, neuromotor and behavioural disturbances in a mouse model for fragile-X-associated tremor/ataxia syndrome (FXTAS)
Debby Van Dam;Vanessa Errijgers;R. Frank Kooy;Rob Willemsen.
Behavioural Brain Research (2005)
Spatial learning, contextual fear conditioning and conditioned emotional response in Fmr1 knockout mice
Debby Van Dam;Rudi D'Hooge;Ehud Hauben;Edwin Reyniers.
Behavioural Brain Research (2000)
Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain
Divya Raj;Zhuoran Yin;Marjolein Breur;Janine Doorduin.
Frontiers in Molecular Neuroscience (2017)
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