His primary areas of investigation include Neuroscience, Alzheimer's disease, Cell biology, Disease and Tau protein. His Neuroscience study incorporates themes from Substantia nigra, Transgene and Frontotemporal dementia. His Frontotemporal dementia research includes elements of Axoplasmic transport, Genetically modified mouse and Trinucleotide repeat expansion.
Lars M. Ittner has researched Alzheimer's disease in several fields, including Endocrinology, Crosstalk and Degenerative disease. His work carried out in the field of Cell biology brings together such families of science as Excitotoxicity and Postsynaptic potential. His Disease research is multidisciplinary, incorporating perspectives in Neuroprotection and Molecular pathway.
Lars M. Ittner mainly investigates Genetically modified mouse, Neuroscience, Cell biology, Transgene and Disease. His Genetically modified mouse research integrates issues from Endocrinology, Tau protein, Pathology, Internal medicine and Tauopathy. His Neuroscience research incorporates elements of Dementia, Frontotemporal dementia, Amyotrophic lateral sclerosis, Excitotoxicity and Alzheimer's disease.
His study in Cell biology is interdisciplinary in nature, drawing from both Gene expression and Immunology. His biological study deals with issues like Molecular biology, which deal with fields such as Calcitonin gene-related peptide. His research in Disease intersects with topics in Treatment strategy and Pathological.
His main research concerns Neuroscience, Genetically modified mouse, Tau protein, Disease and Cell biology. His Neuroscience research includes themes of Alzheimer's disease, Phenotype, Hyperphosphorylation and Excitotoxicity. Genetically modified mouse is the subject of his research, which falls under Transgene.
His Transgene research incorporates themes from Amyotrophic lateral sclerosis, Neurodegeneration and Pathology. The various areas that Lars M. Ittner examines in his Disease study include Epothilone D and Pharmacology. The Cell biology study combines topics in areas such as Tissue engineering, Cell culture and Gene expression.
Lars M. Ittner mainly focuses on Neuroscience, Disease, Tau protein, Alzheimer's disease and Frontotemporal dementia. His studies in Neuroscience integrate themes in fields like Neuroinflammation, Amyotrophic lateral sclerosis, Neurodegeneration and MAPK/ERK pathway. Disease is a subfield of Pathology that Lars M. Ittner studies.
His research integrates issues of Genetically modified mouse and Viral vector in his study of Pathology. In his study, Amyloid is inextricably linked to Endocrinology, which falls within the broad field of Alzheimer's disease. The study incorporates disciplines such as Neuropathology and Pathological in addition to Frontotemporal dementia.
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Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
Lars M. Ittner;Yazi D. Ke;Fabien Delerue;Mian Bi.
Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease
Lars M. Ittner;Jürgen Götz.
Nature Reviews Neuroscience (2011)
Animal models of Alzheimer's disease and frontotemporal dementia
Jürgen Götz;Lars M. Ittner.
Nature Reviews Neuroscience (2008)
Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice
Virginie Rhein;Xiaomin Song;Andreas Wiesner;Lars M. Ittner.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease.
Karl S Lang;Mike Recher;Tobias Junt;Alexander A Navarini.
Nature Medicine (2005)
Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models
Janet van Eersel;Yazi D. Ke;Xin Liu;Fabien Delerue.
Proceedings of the National Academy of Sciences of the United States of America (2010)
The frontotemporal dementia-motor neuron disease continuum.
James R Burrell;James R Burrell;Glenda M Halliday;Glenda M Halliday;Jillian J Kril;Lars M Ittner;Lars M Ittner.
The Lancet (2016)
Tau aggregation and its interplay with amyloid-β.
Rebecca M. Nisbet;Juan‑Carlos Polanco;Lars M. Ittner;Jürgen Götz.
Acta Neuropathologica (2015)
Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling.
Maurice Kléber;Hye-Youn Lee;Heiko Wurdak;Johanna Buchstaller.
Journal of Cell Biology (2005)
Neuronal MicroRNA Deregulation in Response to Alzheimer's Disease Amyloid-β
Nicole Schonrock;Yazi D. Ke;David Humphreys;Matthias Staufenbiel.
PLOS ONE (2010)
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