David Blum

Overview

Best Publications

• Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease.

  David Blum;Sakina Torch;Nathalie Lambeng;Marie-France Nissou

  1615
  Citations

• NLRP3 inflammasome activation drives tau pathology

  Christina Ising;Carmen Venegas;Shuangshuang Zhang;Hannah Scheiblich

  1432
  Citations

• 3‐Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease

  Emmanuel Brouillet;Carine Jacquard;Nicolas Bizat;David Blum

  411
  Citations

• Biochemistry of Tau in Alzheimer’s disease and related neurological disorders

  Nicolas Sergeant;Alexis Bretteville;Malika Hamdane;Marie-Laure Caillet-Boudin

  350
  Citations

• Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?

  Cyril Laurent;Luc Buée;David Blum;David Blum

  344
  Citations

• Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology.

  Annerieke Sierksma;Ashley Lu;Renzo Mancuso;Nicola Fattorelli

  291
  Citations

• Tau phosphorylation and sevoflurane anesthesia: an association to postoperative cognitive impairment.

  Le Freche H;Brouillette J;Fernandez-Gomez Fj;Patin P

  281
  Citations

• Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy

  Cyril Laurent;Guillaume Dorothée;Guillaume Dorothée;Stéphane Hunot;Elodie Martin

  275
  Citations

• Targeting phospho-Ser422 by active Tau Immunotherapy in the THYTau22 mouse model: a suitable therapeutic approach

  Laetitia Troquier;Raphaelle Caillierez;Sylvie Burnouf;Francisco J Fernandez-Gomez

  233
  Citations

• Beneficial effects of caffeine in a transgenic model of Alzheimer's disease-like tau pathology.

  Cyril Laurent;Cyril Laurent;Sabiha Eddarkaoui;Sabiha Eddarkaoui;Maxime Derisbourg;Maxime Derisbourg;Antoine Leboucher;Antoine Leboucher

  227
  Citations

• Atypical, non-standard functions of the microtubule associated Tau protein

  Ioannis Sotiropoulos;Marie-Christine Galas;Joana M. Silva;Efthimios Skoulakis

  218
  Citations

• Tau deletion promotes brain insulin resistance.

  Elodie Marciniak;Antoine Leboucher;Emilie Caron;Tariq Ahmed;Tariq Ahmed

  215
  Citations

• Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology.

  Karim Belarbi;Sylvie Burnouf;Francisco-Jose Fernandez-Gomez;Cyril Laurent

  215
  Citations

• Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid-β1–42 Oligomers Are Revealed In Vivo by Using a Novel Animal Model

  Jonathan Brouillette;Raphaëlle Caillierez;Nadège Zommer;Claire Alves-Pires

  210
  Citations

• Clinical potential of minocycline for neurodegenerative disorders.

  David Blum;Abdelwahed Chtarto;Liliane Tenenbaum;Jacques Brotchi

  199
  Citations

• IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease

  Helena C. Brigas;Miguel Ribeiro;Joana E. Coelho;Rui Gomes;Rui Gomes

  194
  Citations

• A2A adenosine receptor deletion is protective in a mouse model of Tauopathy.

  C Laurent;C Laurent;S Burnouf;S Burnouf;B Ferry;V L Batalha

  189
  Citations

• Hypothalamic Alterations in Neurodegenerative Diseases and Their Relation to Abnormal Energy Metabolism.

  Pauline Vercruysse;Didier Vieau;David Blum;Åsa Petersén

  185
  Citations

• Age-related shift in LTD is dependent on neuronal adenosine A2A receptors interplay with mGluR5 and NMDA receptors

  Mariana Temido-Ferreira;Diana G. Ferreira;Vânia L. Batalha;Inês Marques-Morgado

  177
  Citations

• The Chemokine MIP-1α/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory.

  Elodie Marciniak;Elodie Marciniak;Emilie Faivre;Emilie Faivre;Patrick Dutar;Claire Alves Pires;Claire Alves Pires

  175
  Citations

• Extracellular toxicity of 6-hydroxydopamine on PC12 cells.

  David Blum;Sakina Torch;Marie-France Nissou;Alim-Louis Benabid

  173
  Citations

• Adenosine receptors and Huntington's disease: implications for pathogenesis and therapeutics

  David Blum;Raphaël Hourez;Marie-Christine Galas;Patrizia Popoli

  166
  Citations