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D-Index & Metrics

Medicine

D-Index
88
Citations
31130
World Ranking
13075
National Ranking
156

Overview

Catherine Ledent is affiliated with the Université Libre de Bruxelles in Belgium and has a research focus spanning biochemistry, genetics, molecular biology, and medicine. Their work encompasses several subfields including physiology, molecular biology, genetics, cell biology, and pharmacology.

The scientist's research topics cover a variety of areas such as adenosine and purinergic signaling, nitric oxide and endothelin effects, receptor mechanisms and signaling, genetic and kidney cyst diseases, renal and related cancers, hedgehog signaling pathway studies, and asthma and respiratory diseases.

Among their recent papers are:

  • "CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors" (2022, Neuron)
  • "Limonene-induced activation of A2A adenosine receptors reduces airway inflammation and reactivity in a mouse model of asthma" (2020, Purinergic Signalling)
  • "Peripheral versus central mechanisms of the cannabinoid type 2 receptor agonist AM1710 in a mouse model of neuropathic pain" (2020, Brain and Behavior)
  • "Diabetes and Cannabinoid CB1 receptor deficiency promote similar early onset aging-like changes in the skin" (2021, Experimental Gerontology)
  • "Fit-for-purpose based testing and validation of antibodies to amino- and carboxy-terminal domains of cannabinoid receptor 1" (2021, Histochemistry and Cell Biology)

Frequent co-authors include:

  • S. Jamal Mustafa
  • Stephen L. Tilley
  • Emir Erkol
  • Adèle Herpoel
  • Angéline Bilheu

The scientist has published multiple articles in notable venues, with frequent publication outlets including:

  • The FASEB Journal
  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuron
  • Purinergic Signalling

Best Publications

  • Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB1 Receptor Knockout Mice

    Catherine Ledent;Olga Valverde;Gregorio Cossu;François Petitet

  • Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor.

    Catherine Ledent;Jean-Marie Vaugeois;Serge N. Schiffmann;Thierry Pedrazzini

  • Distribution of CB1 cannabinoid receptors in the amygdala and their role in the control of GABAergic transmission

    István Katona;Ede A. Rancz;László Acsády;Catherine Ledent

  • CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis.

    Fatima Teixeira-Clerc;Boris Julien;Boris Julien;Pascale Grenard;Pascale Grenard;Jeanne Tran Van Nhieu;Jeanne Tran Van Nhieu

  • Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations.

    Norbert Hájos;István Katona;S S Naiem;Ken Mackie

  • Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus.

    Norbert Hájos;Catherine Ledent;Tamás F Freund

  • Molecular Composition of the Endocannabinoid System at Glutamatergic Synapses

    István Katona;Gabriella M. Urbán;Matthew Wallace;Catherine Ledent

  • Involvement of CB1 cannabinoid receptors in emotional behaviour.

    Miquel Martin;Catherine Ledent;Marc Parmentier;Rafael Maldonado

  • Expression of members of the putative olfactory receptor gene family in mammalian germ cells

    Marc Parmentier;Frédérick Libert;Stéphane Schurmans;Serge N. Schiffmann

  • Metabotropic glutamate receptors drive the endocannabinoid system in hippocampus.

    Namita Varma;Gregory C. Carlson;Catherine Ledent;Bradley E. Alger

  • Cardioprotection by Ecto-5′-Nucleotidase (CD73) and A2B Adenosine Receptors

    Tobias Eckle;Thomas Krahn;Almut Grenz;David Köhler

  • Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells.

    Katarzyna Maresz;Gareth Pryce;Gareth Pryce;Eugene D Ponomarev;Giovanni Marsicano

  • Cannabinoids inhibit neurodegeneration in models of multiple sclerosis

    Gareth Pryce;Zubair Ahmed;Deborah J. R. Hankey;Samuel J. Jackson

  • Regulation of Extracellular Signal-Regulated Kinase by Cannabinoids in Hippocampus

    Pascal Derkinderen;Emmanuel Valjent;Emmanuel Valjent;Madeleine Toutant;Jean-Christophe Corvol

  • The effects of genetic and pharmacological blockade of the CB1 cannabinoid receptor on anxiety.

    József Haller;N Bakos;M Szirmay;Catherine Ledent

  • The stimulant effects of caffeine on locomotor behaviour in mice are mediated through its blockade of adenosine A2A receptors

    Malika El Yacoubi;Catherine Ledent;Jean-François Ménard;Marc Parmentier

  • Activation of muscarinic acetylcholine receptors enhances the release of endogenous cannabinoids in the hippocampus

    Jimok Kim;Masako Isokawa;Catherine Ledent;Bradley E. Alger

  • Endocannabinoid signaling in rat somatosensory cortex: Laminar differences and involvement of specific interneuron types

    Ágnes L. Bodor;István Katona;Gábor Nyíri;Ken Mackie

  • Ephrin signalling controls brain size by regulating apoptosis of neural progenitors

    Vanessa Depaepe;Nathalie Suarez-Gonzalez;Audrey Dufour;Lara Passante

  • Context-dependent effects of CB1 cannabinoid gene disruption on anxiety-like and social behaviour in mice.

    József Haller;Balázs Varga;Catherine Ledent;István Barna

Frequent Co-Authors

Marc Parmentier
Marc Parmentier Université Libre de Bruxelles
Olga Valverde
Olga Valverde Pompeu Fabra University
Rafael Maldonado
Rafael Maldonado Pompeu Fabra University
Gilbert Vassart
Gilbert Vassart Université Libre de Bruxelles
Jacques Emile Dumont
Jacques Emile Dumont Université Libre de Bruxelles
Ian Kitchen
Ian Kitchen University of Surrey
Andrew J. Lawrence
Andrew J. Lawrence Florey Institute of Neuroscience and Mental Health
Serge N. Schiffmann
Serge N. Schiffmann Université Libre de Bruxelles
Tamás F. Freund
Tamás F. Freund Institute of Experimental Medicine
David Blum
David Blum University of Lille

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