2026 Karl Harlos: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	73	6025	5554	462	429	325	16743

Overview

Karl Harlos is affiliated with the University of Oxford in the United Kingdom. Their research spans several interconnected fields, primarily within Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. This work includes extensive focus on molecular and cellular processes related to immune function and infectious diseases.

The main fields of study for Karl Harlos include:

Biochemistry, Genetics and Molecular Biology
Immunology and Microbiology
Medicine

Their subfields of expertise involve:

Molecular Biology
Immunology
Epidemiology
Cell Biology
Infectious Diseases

Karl Harlos's research covers core topics such as:

Immune Cell Function and Interaction
Immunotherapy and Immune Responses
RNA and protein synthesis mechanisms
T-cell and B-cell Immunology
Wnt/β-catenin signaling in development and cancer
HIV Research and Treatment
Axon Guidance and Neuronal Signaling

Among the recent papers authored or co-authored by Karl Harlos are:

Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines (2021), Nature Communications
Structural basis of semaphorin-plexin cis interaction (2020), The EMBO Journal
Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity (2022), Communications Biology
Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes (2022), Cell Reports
Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies (2022), mBio

Karl Harlos frequently collaborates with several other researchers, including:

E. Yvonne Jones
M. Yogavel
Amit Sharma
Daniel Rozbeský
Yuguang Zhao

Publication venues in which Karl Harlos has often published include:

bioRxiv (Cold Spring Harbor Laboratory)
Nature Communications
mBio
Structure
The EMBO Journal

Best Publications

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.

Wai-Ching Hon;Michael I. Wilson;Karl Harlos;Timothy D. W. Claridge

897
Citations
A functional and structural basis for TCR cross-reactivity in multiple sclerosis

Heather L.E. Lang;Helle Jacobsen;Helle Jacobsen;Shinji Ikemizu;Christina Andersson;Christina Andersson

737
Citations
Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes

Peter L. Roach;Ian J. Clifton;Vilmos Fülöp;Karl Harlos

532
Citations
Tick histamine-binding proteins: isolation, cloning, and three-dimensional structure.

G.C. Paesen;P.L. Adams;K. Harlos;P.A. Nuttall

401
Citations
Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2.

E Y Jones;S J Davis;A F Williams;K Harlos

387
Citations
Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.

Zhihong Zhang;Jingshan Ren;David K. Stammers;Jack E. Baldwin

340
Citations
Structural basis of substrate discrimination and integrin binding by autotaxin

Jens Hausmann;Satwik Kamtekar;Evangelos Christodoulou;Jacqueline E Day

331
Citations
Structure of Human Cd1B with Bound Ligands at 2.3 A, a Maze for Alkyl Chains

Stephan D. Gadola;Stephan D. Gadola;Nathan R. Zaccai;Karl Harlos;Dawn Shepherd

316
Citations
Initiation of T cell signaling by CD45 segregation at 'close contacts'

Veronica T Chang;Ricardo A Fernandes;Kristina A Ganzinger;Steven F Lee

311
Citations
Crystal structure of the extracellular region of human tissue factor

K. Harlos;D. M. A. Martin;D. P. O'Brien;E. Y. Jones

304
Citations
Structure and dimerization of a soluble form of B7-1.

S Ikemizu;R J Gilbert;R J Gilbert;J A Fennelly;A V Collins

295
Citations
A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization.

T.S. Walter;J.M. Diprose;C.J. Mayo;C. Siebold

286
Citations
The refined structure of the quinoprotein methanol dehydrogenase from Methylobacterium extorquens at 1.94 å

Minakshi Ghosh;Chris Anthony;Karl Harlos;Matthew G Goodwin

269
Citations
Toremifene interacts with and destabilizes the Ebola virus glycoprotein.

Yuguang Zhao;Jingshan Ren;Karl Harlos;Daniel M. Jones

265
Citations
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly

E Seiradake;K Harlos;G Sutton;A.R Aricescu

252
Citations
Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution.

E. Y. Jones;K. Harlos;M. J. Bottomley;R. C. Robinson

247
Citations
Control of the structure and fluidity of phosphatidylglycerol bilayers by pH titration.

Anthony Watts;Karl Harlos;Wilfried Maschke;Derek Marsh

246
Citations
T Cell-Mediated Autoimmune Disease Due to Low-Affinity Crossreactivity to Common Microbial Peptides

Maria Harkiolaki;Samantha L. Holmes;Samantha L. Holmes;Pia Svendsen;Jon W. Gregersen

238
Citations
Structural basis of superantigen action inferred from crystal structure of toxic-shock syndrome toxin-1.

K R Acharya;E F Passalacqua;E Y Jones;K Harlos

224
Citations
Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.

D Hatherley;S C Graham;J Turner;K Harlos

220
Citations