D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 62 Citations 14,139 175 World Ranking 6997 National Ranking 529

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • DNA

Jingshan Ren mainly investigates Virology, Reverse transcriptase, Stereochemistry, Drug resistance and Virus. As part of his studies on Virology, he frequently links adjacent subjects like Plasma protein binding. His Reverse transcriptase study integrates concerns from other disciplines, such as Hydrogen bond, Nucleotidyltransferase, Binding site and Nucleoside.

As a member of one scientific family, Jingshan Ren mostly works in the field of Binding site, focusing on Protein subunit and, on occasion, Mutant, Molecular biology and DNA polymerase. His work deals with themes such as Crystallography, Polymerase, Protein structure and Active site, which intersect with Stereochemistry. His study looks at the intersection of Virus and topics like Epitope with Peptide library, Viral entry, Neutralization, Peptide sequence and Allosteric regulation.

His most cited work include:

  • High resolution structures of HIV-1 RT from four RT-inhibitor complexes. (418 citations)
  • Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors. (393 citations)
  • Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors (278 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Virology, Stereochemistry, Biochemistry, Reverse transcriptase and Virus. His Virology research includes elements of Epitope, Antibody and Mutant. His Stereochemistry study combines topics in areas such as Crystal structure, Active site, Substrate, Enzyme and Aspergillus nidulans.

His Reverse transcriptase research is multidisciplinary, relying on both Molecular biology, Nucleotidyltransferase, Drug resistance and Nucleoside. His Virus study combines topics from a wide range of disciplines, such as RNA, Picornavirus and Recombinant DNA. His study in Binding site is interdisciplinary in nature, drawing from both Plasma protein binding and Protein subunit.

He most often published in these fields:

  • Virology (36.72%)
  • Stereochemistry (24.29%)
  • Biochemistry (21.47%)

What were the highlights of his more recent work (between 2017-2021)?

  • Virology (36.72%)
  • Antibody (9.60%)
  • Virus (20.90%)

In recent papers he was focusing on the following fields of study:

Jingshan Ren focuses on Virology, Antibody, Virus, Epitope and Neutralization. In the subject of general Virology, his work in Viral replication is often linked to Severe acute respiratory syndrome coronavirus 2, thereby combining diverse domains of study. The study incorporates disciplines such as Immune system and Binding site in addition to Antibody.

In his study, Recombinant DNA is strongly linked to Antigen, which falls under the umbrella field of Binding site. Jingshan Ren has researched Neutralization in several fields, including Serum samples, Cell entry, Immunity and Vaccination. He interconnects Protein structure, Protein domain and Ebolavirus in the investigation of issues within Glycoprotein.

Between 2017 and 2021, his most popular works were:

  • Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2. (147 citations)
  • Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike. (129 citations)
  • Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. (94 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

Jingshan Ren mainly focuses on Virology, Antibody, Epitope, Virus and Neutralization. Virology and Glycoprotein are frequently intertwined in his study. His biological study spans a wide range of topics, including Protein structure and Binding site.

The Protein structure study combines topics in areas such as Peptide library and Plasma protein binding. The concepts of his Binding site study are interwoven with issues in Protein domain, Neutralizing antibody and Antigen. All of his Virus and Viral entry and Viral protein investigations are sub-components of the entire Virus study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

High resolution structures of HIV-1 RT from four RT-inhibitor complexes.

J Ren;R Esnouf;E Garman;D Somers.
Nature Structural & Molecular Biology (1996)

700 Citations

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors.

Robert Esnouf;Jingshan Ren;Carl Ross;Yvonne Jones.
Nature Structural & Molecular Biology (1995)

635 Citations

Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors

A. L. Hopkins;Jingshan Ren;R. M. Esnouf;B. E. Willcox.
Journal of Medicinal Chemistry (1996)

424 Citations

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.

J Huo;J Huo;A Le Bas;A Le Bas;R R Ruza;Duyvesteyn Hme..
Nature Structural & Molecular Biology (2020)

385 Citations

A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71

Xiangxi Wang;Wei Peng;Jingshan Ren;Zhongyu Hu.
Nature Structural & Molecular Biology (2012)

384 Citations

Structure and functionality in flavivirus NS-proteins: Perspectives for drug design

Michela Bollati;Karin Alvarez;René Assenberg;Cécile Baronti.
Antiviral Research (2010)

352 Citations

Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase.

Jingshan Ren;John Milton;Kurt L. Weaver;Steven A. Short.
Structure (2000)

343 Citations

Lysine methylation as a routine rescue strategy for protein crystallization.

Thomas S. Walter;Christoph Meier;Rene Assenberg;Kin Fai Au.
Structure (2006)

335 Citations

Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.

Zhihong Zhang;Jingshan Ren;David K. Stammers;Jack E. Baldwin.
Nature Structural & Molecular Biology (2000)

328 Citations

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike.

Jiandong Huo;Jiandong Huo;Yuguang Zhao;Jingshan Ren;Daming Zhou.
Cell Host & Microbe (2020)

267 Citations

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