Jonathan M. Grimes

What is he best known for?

The fields of study he is best known for:

• Gene
• DNA
• Virus

His primary scientific interests are in Virology, RNA, Protein structure, Biophysics and Molecular biology. His studies in Virology integrate themes in fields like Protein subunit and Genomics. As part of the same scientific family, he usually focuses on RNA, concentrating on Transcription and intersecting with Double stranded rna.

His Protein structure research is multidisciplinary, incorporating perspectives in Peptide sequence, Sequence alignment and Plasma protein binding, Cell biology. His study in Biophysics is interdisciplinary in nature, drawing from both Bacterial virus, Viral envelope, Viral membrane and Capsid. His work carried out in the field of Molecular biology brings together such families of science as RNA polymerase and Viral protein.

His most cited work include:

• Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas (648 citations)
• The atomic structure of the bluetongue virus core (505 citations)
• A Mechanism for Initiating RNA-Dependent RNA Polymerization (418 citations)

What are the main themes of his work throughout his whole career to date?

Jonathan M. Grimes focuses on Virology, Virus, RNA, Biophysics and Crystallography. His Virology study combines topics in areas such as Crystal structure and Glycoprotein. Jonathan M. Grimes interconnects Vaccinia and Genome in the investigation of issues within Virus.

Jonathan M. Grimes has researched RNA in several fields, including Molecular biology, Polymerase and Transcription. His Biophysics research is multidisciplinary, incorporating elements of Biochemistry and Binding site. His work in Viral protein covers topics such as Protein structure which are related to areas like Plasma protein binding.

He most often published in these fields:

• Virology (39.00%)
• Virus (21.50%)
• RNA (20.00%)

What were the highlights of his more recent work (between 2017-2021)?

• Virology (39.00%)
• Virus (21.50%)
• Polymerase (11.50%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Virology, Virus, Polymerase, RNA and RNA polymerase. He has included themes like Secondary infection and Pathogen in his Virology study. His Viral Structure and Capsid study in the realm of Virus connects with subjects such as Particle packing.

His Polymerase study integrates concerns from other disciplines, such as Viral protein, Protein Data Bank and In vivo. His RNA research incorporates elements of Genome, Computational biology and Viral replication. His studies in Transcription integrate themes in fields like Cytosol and Cell biology.

Between 2017 and 2021, his most popular works were:

• Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19. (256 citations)
• Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent COVID-19 patients (67 citations)
• Structures of influenza A virus RNA polymerase offer insight into viral genome replication (42 citations)

In his most recent research, the most cited papers focused on:

• Gene
• DNA
• Virus

Jonathan M. Grimes mainly investigates RNA, T cell, CD8, Immunology and Cell biology. His RNA research is multidisciplinary, incorporating elements of Genome and Viral replication. The various areas that he examines in his CD8 study include Virus, Innate immune system and Effector.

In his research, Viral protein is intimately related to Antibody, which falls under the overarching field of Virus. His Cell biology course of study focuses on Methylation and Transcription. His research integrates issues of Molecular biology and Reverse transcriptase in his study of Transcription.