Stereochemistry, Structure–activity relationship, Virology, Virus and Chemical synthesis are his primary areas of study. The study incorporates disciplines such as Biological activity and Potency in addition to Stereochemistry. His Structure–activity relationship research is multidisciplinary, incorporating elements of IC50, Benzimidazole and Anti hiv activity.
His Virology research includes elements of Mutation, Efavirenz, Transactivation and Mechanism of action. His Virus research includes themes of Integrase and Molecular biology. His study in Chemical synthesis is interdisciplinary in nature, drawing from both Lactam, Reverse-transcriptase inhibitor, Thiadiazoles, Bicyclic molecule and Enzyme inhibitor.
His primary areas of study are Stereochemistry, Reverse transcriptase, Virology, Structure–activity relationship and In vitro. The concepts of his Stereochemistry study are interwoven with issues in Combinatorial chemistry and Chemical synthesis. His studies examine the connections between Chemical synthesis and genetics, as well as such issues in Reverse-transcriptase inhibitor, with regards to Enzyme inhibitor and Nucleotidyltransferase.
Christophe Pannecouque has included themes like Nevirapine, Mutant and Enzyme in his Reverse transcriptase study. His research links Integrase with Virology. His studies link Cell culture with Structure–activity relationship.
The scientist’s investigation covers issues in Stereochemistry, Reverse transcriptase, Mutant, Etravirine and Combinatorial chemistry. His study in Stereochemistry focuses on Molecular model in particular. His Reverse transcriptase research is multidisciplinary, relying on both Structure–activity relationship, Pyrimidine and Enzyme.
His Enzyme study incorporates themes from In vitro, Viral replication and Virology. In his research on the topic of Mutant, Drug resistance is strongly related with Mutation. His work carried out in the field of Etravirine brings together such families of science as Rilpivirine, Bioavailability, Efavirenz, Nevirapine and Drug discovery.
His scientific interests lie mostly in Stereochemistry, Reverse transcriptase, Diarylpyrimidines, Combinatorial chemistry and Structure–activity relationship. His Stereochemistry research incorporates themes from Mutant and Cytotoxicity. Christophe Pannecouque combines subjects such as Potency and Pyrimidine with his study of Reverse transcriptase.
Christophe Pannecouque has researched Diarylpyrimidines in several fields, including Anti hiv and Efavirenz. His research integrates issues of Cancer cell, Molecular network and Combinatorial Chemistry Techniques in his study of Structure–activity relationship. His Nucleoside Reverse Transcriptase Inhibitor research integrates issues from Hiv treatment, Virus, Virology and Infectious agent.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Tetrazolium-based colorimetric assay for the detection of HIV replication inhibitors: revisited 20 years later
Christophe Pannecouque;Dirk Daelemans;Erik De Clercq.
Nature Protocols (2008)
Susceptibility of HIV-2, SIV and SHIV to various anti-HIV-1 compounds: implications for treatment and postexposure prophylaxis.
Myriam Witvrouw;Christophe Pannecouque;William M Switzer;Thomas M Folks.
Antiviral Therapy (2004)
Synthesis and antiviral activity of new pyrazole and thiazole derivatives
Osama I. El-Sabbagh;Mohamed M. Baraka;Samy M. Ibrahim;Christophe Pannecouque.
European Journal of Medicinal Chemistry (2009)
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV-1 agents
Maria Letizia Barreca;Alba Chimirri;Laura De Luca;Anna-Maria Monforte.
Bioorganic & Medicinal Chemistry Letters (2001)
Synthesis and antiviral activity evaluation of some new 6-substituted 3-(1-adamantyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles.
Marina Kritsanida;Anastasia Mouroutsou;Panagiotis Marakos;Nicole Pouli.
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents.
Maria L. Barreca;Jan Balzarini;Alba Chimirri;Erik De Clercq.
Journal of Medicinal Chemistry (2002)
Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends
Peng Zhan;Christophe Pannecouque;Erik De Clercq;Xinyong Liu.
Journal of Medicinal Chemistry (2016)
Design, synthesis, and evaluation of 2-aryl-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents.
Ravindra K. Rawal;Rajkamal Tripathi;S.B. Katti;Christophe Pannecouque.
Bioorganic & Medicinal Chemistry (2007)
Polyanionic (i.e., polysulfonate) dendrimers can inhibit the replication of human immunodeficiency virus by interfering with both virus adsorption and later steps (reverse transcriptase/integrase) in the virus replicative cycle.
Myriam Witvrouw;Valery Fikkert;Wim Pluymers;Barry Matthews.
Molecular Pharmacology (2000)
Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle.
Els Keyaerts;Leen Vijgen;Christophe Pannecouque;Els Van Damme.
Antiviral Research (2007)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: