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Immunology
Belgium
2023

D-Index & Metrics

Medicine

D-Index
111
Citations
50313
World Ranking
5298
National Ranking
57

Research.com Recognitions

  • 2023 - Research.com Immunology in Belgium Leader Award
  • 2022 - Research.com Immunology in Belgium Leader Award

Overview

Johan Neyts is affiliated with the Rega Institute for Medical Research in Belgium. Their research primarily focuses on the field of Medicine, with a strong emphasis on Infectious Diseases. Their work spans related subfields including Public Health, Environmental and Occupational Health, Epidemiology, Molecular Biology, and Organic Chemistry.

The scientist has contributed extensively to topics such as SARS-CoV-2 and COVID-19 research, COVID-19 clinical research studies, viral gastroenteritis research and epidemiology, mosquito-borne diseases and control, viral infections and immunology research, viral infections and vectors, and animal virus infections studies.

Notable recent publications include:

  • "N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2" (2021, Cell)
  • "Animal models for COVID-19" (2020, Nature)
  • "Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches" (2022, Cell)
  • "Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms" (2020, Science)
  • "α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment" (2020, Journal of Medicinal Chemistry)

Their research has appeared frequently in several publication venues, with the highest number of contributions found in bioRxiv (Cold Spring Harbor Laboratory). Other noteworthy venues include Antiviral Research, Nature Communications, Nature, and the Journal of Medicinal Chemistry.

Frequent coauthors collaborating with Johan Neyts comprise Dirk Jochmans, Rana Abdelnabi, Suzanne J. F. Kaptein, Birgit Weynand, and Steven De Jonghe. These collaborations reflect a strong network within their research domains and contribute to numerous joint publications.

Best Publications

  • Angiogenesis : regulators and clinical applications

    Sandra Liekens;Erik De Clercq;Johan Neyts

  • N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2.

    Matthew McCallum;Anna De Marco;Florian A. Lempp;M. Alejandra Tortorici;M. Alejandra Tortorici

  • Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture

    Adriaan H. de Wilde;Dirk Jochmans;Clara C. Posthuma;Jessika C. Zevenhoven-Dobbe

  • Animal models for COVID-19.

    César Muñoz-Fontela;William E. Dowling;Simon G.P. Funnell;Pierre S. Gsell

  • In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine

    Els Keyaerts;Leen Vijgen;Piet Maes;Johan Neyts

  • α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment

    Linlin Zhang;Daizong Lin;Yuri Kusov;Yong Nian

  • Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

    M. Alejandra Tortorici;M. Alejandra Tortorici;Martina Beltramello;Florian A. Lempp;Dora Pinto

  • An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge

    Guang Yang;Daniel C. Pevear;Marc H. Davies;Marc S. Collett

  • SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.

    Tyler N. Starr;Nadine Czudnochowski;Zhuoming Liu;Fabrizia Zatta

  • Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug

    Eloise Mastrangelo;Margherita Pezzullo;Tine De Burghgraeve;Suzanne Kaptein

  • Structure and functionality in flavivirus NS-proteins: Perspectives for drug design

    Michela Bollati;Karin Alvarez;René Assenberg;Cécile Baronti

  • Favipiravir as a potential countermeasure against neglected and emerging RNA viruses

    Leen Delang;Rana Abdelnabi;Johan Neyts

  • The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model.

    Joanna Zmurko;Rafael E. Marques;Dominique Schols;Erik Verbeken

  • The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro†

    Jan Paeshuyse;Artur Kaul;Erik De Clercq;Brigitte Rosenwirth

  • The Mannose-Specific Plant Lectins From Cymbidium Hybrid and Epipactis Helleborine and the (N-acetylglucosamine)n-specific Plant Lectin From Urtica Dioica Are Potent and Selective Inhibitors of Human Immunodeficiency Virus and Cytomegalovirus Replication in Vitro

    J Balzarini;J Neyts;D Schols;M Hosoya

  • The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase.

    Pieter Leyssen;Jan Balzarini;Erik De Clercq;Johan Neyts

  • Broad betacoronavirus neutralization by a stem helix-specific human antibody.

    Dora Pinto;Dora Pinto;Maximilian M. Sauer;Nadine Czudnochowski;Jun Siong Low;Jun Siong Low

  • Alpha-(1-3)- and alpha-(1-6)-D-mannose-specific plant lectins are markedly inhibitory to human immunodeficiency virus and cytomegalovirus infections in vitro.

    J Balzarini;D Schols;J Neyts;E Van Damme

  • Perspectives for the Treatment of Infections with Flaviviridae

    P Leyssen;E De Clercq;J Neyts

  • HPMPC (cidofovir), PMEA (adefovir) and related acyclic nucleoside phosphonate analogues: a review of their pharmacology and clinical potential in the treatment of viral infections

    L Naesens;R Snoeck;G Andrei;J Balzarini

Frequent Co-Authors

Pieter Leyssen
Pieter Leyssen Rega Institute for Medical Research
Erik De Clercq
Erik De Clercq Rega Institute for Medical Research
Jan Balzarini
Jan Balzarini KU Leuven
Robert Snoeck
Robert Snoeck KU Leuven
Bruno Canard
Bruno Canard Aix-Marseille University
Lieve Naesens
Lieve Naesens Rega Institute for Medical Research
Frank J. M. van Kuppeveld
Frank J. M. van Kuppeveld Utrecht University

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