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Frank J. M. van Kuppeveld

Frank J. M. van Kuppeveld

D-Index & Metrics

Microbiology

D-Index
86
Citations
22102
World Ranking
851
National Ranking
50

Overview

Frank J. M. van Kuppeveld is affiliated with Utrecht University in the Netherlands. Their research spans multiple areas within medicine and molecular biology, with a focus on infectious diseases, immunology, and epidemiology. The primary fields of study include Medicine and Biochemistry, Genetics and Molecular Biology.

The scientist's subfields of study concentrate on:

  • Infectious Diseases
  • Molecular Biology
  • Epidemiology
  • Cardiology and Cardiovascular Medicine
  • Immunology

Van Kuppeveld's main research topics involve:

  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Immunology Research
  • Viral gastroenteritis research and epidemiology
  • Animal Virus Infections Studies
  • Influenza Virus Research Studies
  • Respiratory viral infections research
  • Interferon and immune responses

Recent papers authored or coauthored by van Kuppeveld include:

  • "A human monoclonal antibody blocking SARS-CoV-2 infection," 2020, published in Nature Communications
  • "A human monoclonal antibody blocking SARS-CoV-2 infection," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies," 2021, Nature Communications
  • "SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms," 2021, Nature Communications
  • "A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays," 2021, Nature Communications

Van Kuppeveld frequently collaborates with several researchers, including:

  • Berend-Jan Bosch
  • Wentao Li
  • Daniel L. Hurdiss
  • Cornelis A. M. de Haan
  • Marleen Zwaagstra

The majority of van Kuppeveld's publications appear in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • PLoS Pathogens
  • Proceedings of the National Academy of Sciences
  • Nature

Best Publications

  • A human monoclonal antibody blocking SARS-CoV-2 infection.

    Chunyan Wang;Wentao Li;Dubravka Drabek;Nisreen M.A. Okba

  • Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

    Nai Yun Hsu;Olha Ilnytska;Georgiy Belov;Marianita Santiana

  • The life cycle of non-polio enteroviruses and how to target it.

    Jim Baggen;Hendrik Jan Thibaut;Jeroen R. P. M. Strating;Frank J. M. van Kuppeveld

  • Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

    Christine Burkard;Monique H. Verheije;Oliver Wicht;Sander I. van Kasteren

  • Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A.

    Ruben J.G. Hulswit;Yifei Lang;Mark J.G. Bakkers;Wentao Li

  • Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release

    F.J.M. van Kuppeveld;J.G.J. Hoenderop;R.L.L. Smeets;P.H.G.M. Willems

  • Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein

    Wentao Li;Ruben J. G. Hulswit;Ivy Widjaja;V. Stalin Raj

  • The receptor binding domain of the new middle east respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies

    Huihui Mou;V. Stalin Raj;Frank J. M. van Kuppeveld;Peter J. M. Rottier

  • Broad receptor engagement of an emerging global coronavirus may potentiate its diverse cross-species transmissibility.

    Wentao Li;Ruben J. G. Hulswit;Scott P. Kenney;Ivy Widjaja

  • MDA5 Detects the Double-Stranded RNA Replicative Form in Picornavirus-Infected Cells

    Unknown

  • Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein.

    Jeroen R.P.M. Strating;Jeroen R.P.M. Strating;Lonneke van der Linden;Lonneke van der Linden;Lucian Albulescu;Lucian Albulescu;Joëlle Bigay

  • Enterovirus 2Apro Targets MDA5 and MAVS in Infected Cells

    Qian Feng;Martijn A. Langereis;Marie Lork;Mai Nguyen

  • Rhinovirus Uses a Phosphatidylinositol 4-Phosphate/Cholesterol Counter-Current for the Formation of Replication Compartments at the ER-Golgi Interface

    Pascal S. Roulin;Mark Lötzerich;Federico Torta;Lukas B. Tanner

  • Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

    Eveline Patricia Kindler;Eveline Patricia Kindler;Cristina Gil-Cruz;Julia Spanier;Yize Li

  • Cellular entry of the porcine epidemic diarrhea virus.

    Wentao Li;Frank J.M. van Kuppeveld;Qigai He;Peter J.M. Rottier

  • Small molecule ISRIB suppresses the integrated stress response within a defined window of activation.

    Huib H. Rabouw;Martijn A. Langereis;Aditya A. Anand;Aditya A. Anand;Linda J. Visser

  • Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retrospective analysis of samples from an established cohort.

    Frank J. M. van Kuppeveld;Arjan S de Jong;Kjerstin H W Lanke;Gerald W. Verhaegh

  • PLA2G16 represents a switch between entry and clearance of Picornaviridae

    Jacqueline Staring;Eleonore von Castelmur;Vincent A Blomen;Lisa G van den Hengel

  • GBF1, a Guanine Nucleotide Exchange Factor for Arf, Is Crucial for Coxsackievirus B3 RNA Replication

    Kjerstin H. W. Lanke;Hilde M. van der Schaar;George A. Belov;Qian Feng

  • The Transformation of Enterovirus Replication Structures: a Three-Dimensional Study of Single- and Double-Membrane Compartments

    Ronald W. A. L. Limpens;Hilde M. van der Schaar;Darshan Kumar;Abraham J. Koster

  • Saffold virus, a human Theiler's-like cardiovirus, is ubiquitous and causes infection early in life.

    Jan Zoll;Sandra Erkens Hulshof;Kjerstin Lanke;Frans Verduyn Lunel

  • A viral protein that blocks Arf1-mediated COP-I assembly by inhibiting the guanine nucleotide exchange factor GBF1.

    Els Wessels;Daniël Duijsings;Ting-Kuang Niu;Steffi Neumann

Frequent Co-Authors

Willem J. G. Melchers
Willem J. G. Melchers Radboud University
Kjerstin Lanke
Kjerstin Lanke Radboud University
Berend Jan Bosch
Berend Jan Bosch Utrecht University
Cornelis A. M. de Haan
Cornelis A. M. de Haan Utrecht University
Johan Neyts
Johan Neyts Rega Institute for Medical Research
Raoul J. de Groot
Raoul J. de Groot Utrecht University
Peter J. M. Rottier
Peter J. M. Rottier Utrecht University
Peter H. G. M. Willems
Peter H. G. M. Willems Radboud University
Bart L. Haagmans
Bart L. Haagmans Erasmus University Rotterdam
Gosse J. Adema
Gosse J. Adema Radboud University

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