His primary scientific interests are in Virology, Viral replication, Cell biology, RNA and Endoplasmic reticulum. The various areas that Frank J. M. van Kuppeveld examines in his Virology study include Cell culture and Picornavirus. His Viral replication study incorporates themes from OSBP, Host factor and RNA interference.
His work in the fields of Cell biology, such as Intracellular, Extracellular and Endosome, intersects with other areas such as Protein kinase R. His RNA research is multidisciplinary, incorporating elements of Molecular biology, Transcription and Mutant. His Endoplasmic reticulum study integrates concerns from other disciplines, such as Transport protein and Cytosol.
Frank J. M. van Kuppeveld mainly investigates Virology, Viral replication, Virus, Cell biology and RNA. His work on Enterovirus, Coxsackievirus and Poliovirus as part of general Virology study is frequently linked to Coronavirus, bridging the gap between disciplines. His Coxsackievirus research includes themes of OSBP, PI4KB, Mutant and Oxysterol-binding protein.
His Viral replication study combines topics in areas such as Phosphatidylinositol, Kinase, Biochemistry and Host factor. His studies in Virus integrate themes in fields like Interferon and Receptor. His research combines Molecular biology and RNA.
Frank J. M. van Kuppeveld focuses on Virology, Cell biology, Viral replication, Antibody and Virus. He performs multidisciplinary studies into Virology and Coronavirus in his work. His Cell biology research is multidisciplinary, incorporating perspectives in Integrated stress response and Translation.
His study in Viral replication is interdisciplinary in nature, drawing from both Cell, Gene, Enterovirus, Lipid droplet and Organelle. In general Antibody, his work in Epitope and Seroconversion is often linked to Severe acute respiratory syndrome coronavirus 2 linking many areas of study. His Virus research incorporates elements of Phenotype and Picornavirus.
His primary areas of study are Virology, Monoclonal antibody, Antibody, Viral replication and Cell biology. He studies Virology, namely Viral protein. Frank J. M. van Kuppeveld interconnects Epitope and Pneumonia in the investigation of issues within Monoclonal antibody.
His Viral replication research is multidisciplinary, relying on both Poliovirus, Enterovirus and Neuraminidase. The Cell biology study combines topics in areas such as Differential centrifugation and Picornavirus. His Picornavirus research is multidisciplinary, incorporating elements of Biogenesis, Binding domain, PI4KB, Coxsackievirus and Host factor.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
A human monoclonal antibody blocking SARS-CoV-2 infection.
Chunyan Wang;Wentao Li;Dubravka Drabek;Nisreen M.A. Okba.
Nature Communications (2020)
Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication
Nai Yun Hsu;Olha Ilnytska;Georgiy Belov;Marianita Santiana.
Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.
Christine Burkard;Monique H. Verheije;Oliver Wicht;Sander I. van Kasteren.
PLOS Pathogens (2014)
Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release
F.J.M. van Kuppeveld;J.G.J. Hoenderop;R.L.L. Smeets;P.H.G.M. Willems.
The EMBO Journal (1997)
The receptor binding domain of the new middle east respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies
Huihui Mou;V. Stalin Raj;Frank J. M. van Kuppeveld;Peter J. M. Rottier.
Journal of Virology (2013)
Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A.
Ruben J.G. Hulswit;Yifei Lang;Mark J.G. Bakkers;Wentao Li.
Proceedings of the National Academy of Sciences of the United States of America (2019)
Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein
Wentao Li;Ruben J. G. Hulswit;Ivy Widjaja;V. Stalin Raj.
Proceedings of the National Academy of Sciences of the United States of America (2017)
The life cycle of non-polio enteroviruses and how to target it.
Jim Baggen;Hendrik Jan Thibaut;Jeroen R. P. M. Strating;Frank J. M. van Kuppeveld.
Nature Reviews Microbiology (2018)
Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retrospective analysis of samples from an established cohort.
Frank J. M. van Kuppeveld;Arjan S de Jong;Kjerstin H W Lanke;Gerald W. Verhaegh.
Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein.
Jeroen R.P.M. Strating;Jeroen R.P.M. Strating;Lonneke van der Linden;Lonneke van der Linden;Lucian Albulescu;Lucian Albulescu;Joëlle Bigay.
Cell Reports (2015)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: