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Peter J. M. Rottier

Peter J. M. Rottier

D-Index & Metrics

Microbiology

D-Index
100
Citations
31681
World Ranking
420
National Ranking
29

Overview

Peter J. M. Rottier is affiliated with Utrecht University in the Netherlands. Their research primarily focuses on medicine, with particular expertise in oncology and related subfields.

The scientist has contributed extensively to topics such as HER2/EGFR in cancer research, animal virus infections studies, viral gastroenteritis research and epidemiology, advanced breast cancer therapies, breast cancer treatment studies, virus-based gene therapy research, and cancer immunotherapy and biomarkers.

Recent publications by Peter J. M. Rottier and collaborators include:

  • Spike gene variability in porcine epidemic diarrhea virus as a determinant for virulence, 2025, Journal of Virology
  • 117P Pretherapeutic neutrophil-lymphocyte ratio as prognostic and predictive factors in metastatic breast cancer treated with cyclin dependent kinase 4/6 inhibitors, 2021, Annals of Oncology
  • 104P HELENA: Study of HER2-low as a prEdictive factor of response to Neoadjuvant chemotherapy in eArly breast cancer, 2022, Annals of Oncology
  • 112P Correlation between HER2-negative status and risk of recurrence according to PAM50 score, 2023, ESMO Open
  • 19P HER2-low prognosis in early breast cancer: A CANTO based study (LILAC), 2024, ESMO Open

Frequent co-authors in their work include:

  • Alison Johnson
  • Adeline Morel
  • François Cherifi
  • George Emile
  • A. Da Silva

Peter J. M. Rottier's publications have appeared most often in renowned venues such as:

  • Annals of Oncology
  • ESMO Open
  • Journal of Virology
  • npj Vaccines

Their research spans several key areas within medicine and oncology, addressing complex issues related to cancer biology and viral infections. Specific subfields in which they have published include oncology, infectious diseases, animal science and zoology, pulmonary and respiratory medicine, and cancer research.

Best Publications

  • Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

    V. Stalin Raj;Huihui Mou;Saskia L. Smits;Dick H. W. Dekkers

  • The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex

    Berend Jan Bosch;Ruurd van der Zee;Cornelis A. M. de Haan;Peter J. M. Rottier

  • Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study

    Chantal B.E.M. Reusken;Bart L. Haagmans;Marcel A. Müller;Carlos Gutierrez

  • Nucleocapsid-independent assembly of coronavirus-like particles by co-expression of viral envelope protein genes.

    H. Vennema;G.-J. Godeke;J. W. A. Rossen;W. F. Voorhout

  • Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

    Alexandra C. Walls;M. Alejandra Tortorici;M. Alejandra Tortorici;Berend Jan Bosch;Brandon Frenz

  • Feline Coronavirus Type II Strains 79-1683 and 79-1146 Originate from a Double Recombination between Feline Coronavirus Type I and Canine Coronavirus

    Arnold A. P. M. Herrewegh;Ingrid Smeenk;Marian C. Horzinek;Peter J. M. Rottier

  • Retargeting of Coronavirus by Substitution of the Spike Glycoprotein Ectodomain: Crossing the Host Cell Species Barrier

    Lili Kuo;Gert-Jan Godeke;Martin J. B. Raamsman;Paul S. Masters

  • Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides.

    Berend Jan Bosch;Byron E. E. Martina;Ruurd van der Zee;Jean Lepault

  • Molecular interactions in the assembly of coronaviruses.

    Cornelis A.M. de Haan;Peter J.M. Rottier

  • SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells.

    I-Chueh Huang;Berend Jan Bosch;Fang Li;Wenhui Li

  • Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

    Christine Burkard;Monique H. Verheije;Oliver Wicht;Sander I. van Kasteren

  • Characterization of the budding compartment of mouse hepatitis virus: evidence that transport from the RER to the Golgi complex requires only one vesicular transport step.

    J. Krijnse-Locker;M. Ericsson;P. J. M. Rottier;G. Griffiths

  • Coronavirus M proteins accumulate in the Golgi complex beyond the site of virion budding.

    J Klumperman;J K Locker;A Meijer;M C Horzinek

  • The Genome Organization of the Nidovirales: Similarities and Differences Between Arteri-, Toro-, and Coronaviruses

    Antoine A.F. de Vries;Marian C. Horzinek;Peter J.M. Rottier;Raoul J. de Groot

  • Dissection of the Influenza A Virus Endocytic Routes Reveals Macropinocytosis as an Alternative Entry Pathway

    Erik de Vries;Donna M. Tscherne;Marleen J. Wienholts;Viviana Cobos-Jiménez

  • Cryo-electron tomography of mouse hepatitis virus: Insights into the structure of the coronavirion

    Montserrat Barcena;Gert T. Oostergetel;Willem Bartelink;Frank G. A. Faas

  • Coronavirus particle assembly: primary structure requirements of the membrane protein.

    C. A. M. De Haan;L. Kuo;P. S. Masters;H. Vennema

  • Cathepsin L Functionally Cleaves the Severe Acute Respiratory Syndrome Coronavirus Class I Fusion Protein Upstream of Rather than Adjacent to the Fusion Peptide

    Berend Jan Bosch;Willem Bartelink;Peter J. M. Rottier

  • The receptor binding domain of the new middle east respiratory syndrome coronavirus maps to a 231-residue region in the spike protein that efficiently elicits neutralizing antibodies

    Huihui Mou;V. Stalin Raj;Frank J. M. van Kuppeveld;Peter J. M. Rottier

  • Structural proteins of equine arteritis virus.

    A. A. F. De Vries;E. D. Chirnside;M. C. Horzinek;P. J. M. Rottier

Frequent Co-Authors

Cornelis A. M. de Haan
Cornelis A. M. de Haan Utrecht University
Berend Jan Bosch
Berend Jan Bosch Utrecht University
Marian C. Horzinek
Marian C. Horzinek Utrecht University
Harry Vennema
Harry Vennema Centre for infectious Disease Control (Cib)
Frank J. M. van Kuppeveld
Frank J. M. van Kuppeveld Utrecht University
Herman Egberink
Herman Egberink Utrecht University
Bart L. Haagmans
Bart L. Haagmans Erasmus University Rotterdam
Paul S. Masters
Paul S. Masters New York State Department of Health
Raoul J. de Groot
Raoul J. de Groot Utrecht University
Albert D. M. E. Osterhaus
Albert D. M. E. Osterhaus University of Veterinary Medicine Hannover, Foundation

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