World's Best Scientists 2026 revealed!

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Immunology

D-Index
110
Citations
40740
World Ranking
508
National Ranking
20

Medicine

D-Index
110
Citations
40742
World Ranking
5602
National Ranking
212

Overview

Gosse J. Adema is affiliated with Radboud University in the Netherlands. Their research spans multiple intersecting fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. The scholar has a considerable publication record in Immunology and Molecular Biology, with significant contributions also to Oncology, Cancer Research, and Radiology, Nuclear Medicine and Imaging.

The research topics addressed by Adema focus on diverse aspects of cancer and immunology, including:

  • Cancer, Hypoxia, and Metabolism
  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • Glycosylation and Glycoproteins Research
  • Immune cells in cancer
  • RNA modifications and cancer
  • Immune Response and Inflammation

Adema's recent selected publications highlight ongoing investigations into the tumor immune environment and immune signaling pathways:

  • "Sialoglycans and Siglecs Can Shape the Tumor Immune Microenvironment," 2020, Trends in Immunology
  • "Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation," 2020, Journal for ImmunoTherapy of Cancer
  • "Probing the binding specificities of human Siglecs by cell-based glycan arrays," 2021, Proceedings of the National Academy of Sciences
  • "Targeting Oxidative Phosphorylation to Increase the Efficacy of Radio- and Immune-Combination Therapy," 2021, Clinical Cancer Research
  • "Siglec Signaling in the Tumor Microenvironment," 2021, Frontiers in Immunology

The scientist frequently publishes in specialized venues, notably:

  • Radiotherapy and Oncology
  • Frontiers in Immunology
  • Journal for ImmunoTherapy of Cancer
  • Cellular and Molecular Life Sciences
  • Clinical Cancer Research

Regular collaborators who have co-authored multiple papers with Adema include Johan Bussink, Paul N. Span, Marleen Ansems, Sandra Heskamp, and Lenneke A. M. Cornelissen. These collaborations reflect a concentrated network in the domains of oncology and immunology research.

Best Publications

  • Identification of DC-SIGN, a Novel Dendritic Cell–Specific ICAM-3 Receptor that Supports Primary Immune Responses

    T.B.H. Geijtenbeek;R. Torensma;S.J. van Vliet;G.C.F. van Duijnhoven

  • C-type lectin receptors on dendritic cells and langerhans cells

    Carl G Figdor;Yvette van Kooyk;Gosse J Adema

  • The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells

    Dennis S. U. Lindau;Paul R. Gielen;Michiel Kroesen;Pieter Wesseling;Pieter Wesseling

  • Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy

    I Jolanda M de Vries;W Joost Lesterhuis;Jelle O Barentsz;Pauline Verdijk

  • Toll-like receptor 2 controls expansion and function of regulatory T cells.

    Roger P.M. Sutmuller;Martijn H.M.G.M. den Brok;Matthijs Kramer;Erik J. Bennink

  • Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

    Bart Ferwerda;Gerben Ferwerda;Theo S. Plantinga;Janet A. Willment

  • Toll-Like Receptor 2 Suppresses Immunity against Candida albicans through Induction of IL-10 and Regulatory T Cells

    Mihai G. Netea;Roger Sutmuller;Corinna Hermann;Chantal A. A. Van der Graaf

  • Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes

    A.B.H. Bakker;M.W.J. Schreurs;A.J. de Boer;Y. Kawakami

  • Different faces of the heme-heme oxygenase system in inflammation

    Frank A. D. T. G. Wagener;Hans-Dieter Volk;Dean Willis;Nader G. Abraham

  • A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells

    G.J. Adema;F.C. Hartgers;R.G.G. Verstraten;E. de Vries

  • Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state

    I. Jolanda M. de Vries;Daniëlle J. E. B. Krooshoop;Nicole M. Scharenborg;W. Joost Lesterhuis

  • LAIR-1, a Novel Inhibitory Receptor Expressed on Human Mononuclear Leukocytes

    Linde Meyaard;Gosse J Adema;Chiwen Chang;Erica Woollatt

  • In Situ Tumor Ablation Creates an Antigen Source for the Generation of Antitumor Immunity

    Martijn H. M. G. M. den Brok;Roger P. M. Sutmuller;Robbert van der Voort;Erik J. Bennink

  • Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase.

    Frank A. D. T. G. Wagener;Andreas Eggert;Otto C. Boerman;Wim J. G. Oyen

  • Sialic Acids Sweeten a Tumor's Life

    Christian Büll;Marieke A. Stoel;Martijn H. den Brok;Gosse J. Adema

  • The C-type lectin DC-SIGN (CD209) is an antigen-uptake receptor for Candida albicans on dendritic cells.

    Alessandra Cambi;Karlijn Gijzen;I. Jolanda M. de Vries;Ruurd Torensma

  • NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis.

    Gerben Ferwerda;Stephen E. Girardin;Bart Jan Kullberg;Lionel Le Bourhis

  • Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.

    Kevin M. Dennehy;Gerben Ferwerda;Inês Faro-Trindade;Elwira Pyz

  • Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages.

    Gerben Ferwerda;Friederike Meyer-Wentrup;Bart-Jan Kullberg;Mihai G. Netea

  • Maturation of Dendritic Cells Is a Prerequisite for Inducing Immune Responses in Advanced Melanoma Patients

    I. Jolanda M. de Vries;W. Joost Lesterhuis;Nicole M. Scharenborg;Linda P. H. Engelen

Frequent Co-Authors

Carl G. Figdor
Carl G. Figdor Radboud University
I. Jolanda M. de Vries
I. Jolanda M. de Vries Radboud University
Cornelis J. A. Punt
Cornelis J. A. Punt University of Amsterdam
Mihai G. Netea
Mihai G. Netea Radboud University
Pieter Wesseling
Pieter Wesseling University of Amsterdam
Gerty Schreibelt
Gerty Schreibelt Radboud University
Ruurd Torensma
Ruurd Torensma Radboud University
Stefan Nierkens
Stefan Nierkens University Medical Center Utrecht
Bart Jan Kullberg
Bart Jan Kullberg Radboud University
Frank J. M. van Kuppeveld
Frank J. M. van Kuppeveld Utrecht University

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