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Immunology

D-Index
82
Citations
22758
World Ranking
1513
National Ranking
10

Medicine

D-Index
82
Citations
22764
World Ranking
16214
National Ranking
187

Overview

Outi Vaarala is affiliated with the University of Helsinki in Finland. Their research spans multiple disciplines within medicine and biochemistry, genetics, and molecular biology, with a strong focus on diabetes and related disorders.

The primary fields of study for Vaarala include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

They have contributed extensively to subfields such as genetics, immunology, pulmonary and respiratory medicine, nutrition and dietetics, and epidemiology.

Topics central to their research involve:

  • Diabetes and associated disorders
  • Infant Nutrition and Health
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Digestive system and related health
  • Sleep and Wakefulness Research
  • Breastfeeding Practices and Influences

Vaarala has published numerous papers, with recent examples including:

  • Fungal Dysbiosis and Intestinal Inflammation in Children With Beta-Cell Autoimmunity (2020, Frontiers in Immunology)
  • Enhanced influenza A H1N1 T cell epitope recognition and cross-reactivity to protein-O-mannosyltransferase 1 in Pandemrix-associated narcolepsy type 1 (2021, Nature Communications)
  • Serum 25-hydroxyvitamin D concentration in childhood and risk of islet autoimmunity and type 1 diabetes: the TRIGR nested case-control ancillary study (2020, Diabetologia)
  • Ultrasensitive DNA Immune Repertoire Sequencing Using Unique Molecular Identifiers (2020, Clinical Chemistry)
  • Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function (2020, Translational Psychiatry)

The frequent venues where Vaarala's work has appeared include:

  • Frontiers in Immunology
  • Diabetologia
  • Clinical Chemistry
  • Nature Communications
  • PLoS ONE

The scientist has collaborated regularly with a number of coauthors, notably:

  • Mikael Knip
  • Jarno Honkanen
  • Maija E. Miettinen
  • Sari Niinistö
  • Jorma Ilonen

Best Publications

  • The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

    Aleksandar D. Kostic;Aleksandar D. Kostic;Dirk Gevers;Heli Siljander;Tommi Vatanen;Tommi Vatanen

  • Environmental Triggers and Determinants of Type 1 Diabetes

    Mikael Knip;Riitta Veijola;Suvi M. Virtanen;Heikki Hyöty

  • The “Perfect Storm” for Type 1 Diabetes: The Complex Interplay Between Intestinal Microbiota, Gut Permeability, and Mucosal Immunity

    Outi Vaarala;Mark A. Atkinson;Josef Neu

  • Fecal Microbiota Composition Differs Between Children With β-Cell Autoimmunity and Those Without

    Marcus C. de Goffau;Kristiina Luopajärvi;Mikael Knip;Jorma Ilonen;Jorma Ilonen

  • GAD treatment and insulin secretion in recent-onset type 1 diabetes

    Johnny Ludvigsson;Maria Faresjö;Maria Hjorth;Stina Axelsson

  • AS03 Adjuvanted AH1N1 Vaccine Associated with an Abrupt Increase in the Incidence of Childhood Narcolepsy in Finland

    Hanna Nohynek;Jukka Jokinen;Markku Partinen;Outi Vaarala

  • Environmental factors in the etiology of type 1 diabetes

    Hans K. Åkerblom;Outi Vaarala;Heikki Hyöty;Jorma Ilonen

  • Crossreaction between antibodies to oxidised low-density lipoprotein and to cardiolipin in systemic lupus erythematosus

    O. Vaarala;K. Aho;T. Palosuo;G. Alfthan

  • Lactobacillus GG effect in increasing IFN-gamma production in infants with cow's milk allergy.

    Emma Pohjavuori;Mirva Viljanen;Riitta Korpela;Mikael Kuitunen

  • Anti-Cardiolipin Antibodies and Risk of Myocardial Infarction in a Prospective Cohort of Middle-Aged Men

    Outi Vaarala;Matti Mänttäri;Vesa Manninen;Leena Tenkanen

  • IL-17 Immunity in Human Type 1 Diabetes

    Jarno Honkanen;Janne K. Nieminen;Ru Gao;Kristiina Luopajarvi

  • Dietary intervention in infancy and later signs of beta-cell autoimmunity.

    Mikael Knip;Suvi M. Virtanen;Karri Seppä;Jorma Ilonen

  • Antibody Against Oxidized Low-Density Lipoprotein Predicting Myocardial Infarction

    Marja Puurunen;Matti Mänttäri;Vesa Manninen;Leena Tenkanen

  • Anticardiolipin response in acute infections.

    Outi Vaarala;Timo Palosuo;Marjaana Kleemola;Kimmo Aho

  • Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination.

    Markku Partinen;Birgitte Rahbek Kornum;Giuseppe Plazzi;Poul Jennum

  • Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2

    Syed Sohail Ahmed;Wayne Volkmuth;José Duca;Lorenzo Corti

  • A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children

    Malin Fagerås Böttcher;Mounira Hmani-Aifa;Anna Lindström;Maria Christina Jenmalm

  • Cow's milk formula feeding induces primary immunization to insulin in infants at genetic risk for type 1 diabetes.

    Outi Vaarala;Mikael Knip;Johanna Paronen;Anu-Maaria Hämäläinen

  • IL‐23/IL‐17 immunity as a hallmark of Crohn's disease

    Veera Hölttä;Paula Klemetti;Taina Sipponen;Mia Westerholm-Ormio

  • Patterns of β-cell autoantibody appearance and genetic associations during the first years of life.

    Jorma Ilonen;Anna Hammais;Antti-Pekka Laine;Johanna Lempainen;Johanna Lempainen

  • Dynamic association of human insulin receptor with lipid rafts in cells lacking caveolae

    Saara Vainio;Sanna Heino;Jan-Eric Månsson;Pam Fredman

Frequent Co-Authors

Jorma Ilonen
Jorma Ilonen University of Turku
Mikael Knip
Mikael Knip University of Helsinki
Suvi M. Virtanen
Suvi M. Virtanen Tampere University
Johnny Ludvigsson
Johnny Ludvigsson Linköping University
Erkki Savilahti
Erkki Savilahti University of Helsinki
Hans K. Åkerblom
Hans K. Åkerblom University of Helsinki
Juha Pekkanen
Juha Pekkanen University at Buffalo, State University of New York
Ilkka Julkunen
Ilkka Julkunen University of Turku
Heikki Hyöty
Heikki Hyöty Tampere University
Markku Partinen
Markku Partinen University of Helsinki

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