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Matej Orešič

Matej Orešič

D-Index & Metrics

Medicine

D-Index
110
Citations
48355
World Ranking
5526
National Ranking
118

Overview

Matej Orešič is affiliated with Örebro University in Sweden. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, encompassing 170 and 134 publications in these areas respectively. Within these broad domains, their subfields of focus include Molecular Biology, Epidemiology, Physiology, Endocrinology, Diabetes and Metabolism, and Genetics.

Orešič's research topics cover a range of biomedical and health-related studies, notably:

  • Metabolomics and Mass Spectrometry Studies
  • Liver Disease Diagnosis and Treatment
  • Diet and Metabolism Studies
  • Per- and Polyfluoroalkyl Substances Research
  • Gut Microbiota and Health
  • Diabetes and Associated Disorders
  • Diet, Metabolism, and Disease

The scholar has contributed frequently to several journals and publication venues. Their most common outlets include bioRxiv (Cold Spring Harbor Laboratory) with 23 publications, Journal of Hepatology with 10, Environment International with 6, Metabolites with 5, and Analytical Chemistry with 4.

Among recent notable papers are:

  • "Traumatic brain injury: progress and challenges in prevention, clinical care, and research" (2022) published in The Lancet Neurology
  • "Integrative analysis of multimodal mass spectrometry data in MZmine 3" (2023) published in Nature Biotechnology
  • "Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests" (2021) published in Nature Reviews Gastroenterology & Hepatology
  • "Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis" (2020) published in Science Translational Medicine
  • "Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis" (2021) published in Journal of Hepatology

Matej Orešič often collaborates with several researchers, with frequent co-authors including Tuulia Hyötyläinen, Alex M. Dickens, Partho Sen, Santosh Lamichhane, and Mikael Knip.

Best Publications

  • MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data

    Tomáš Pluskal;Sandra Castillo;Alejandro Villar-Briones;Matej Orešič

  • Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist.

    Sama I. Sayin;Annika Wahlström;Jenny Felin;Sirkku Jäntti

  • Human gut microbes impact host serum metabolome and insulin sensitivity

    Helle Krogh Pedersen;Valborg Gudmundsdottir;Henrik B. Nielsen;Tuulia Hyötyläinen;Tuulia Hyötyläinen

  • The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

    Aleksandar D. Kostic;Aleksandar D. Kostic;Dirk Gevers;Heli Siljander;Tommi Vatanen;Tommi Vatanen

  • MZmine: toolbox for processing and visualization of mass spectrometry based molecular profile data

    Mikko Katajamaa;Jarkko Miettinen;Matej Orešič

  • Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

    Miguel González López;Miguel González López;Luis Varela;María J. Sánchez Vazquez;Sergio Rodriguez-Cuenca

  • Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis

    David Sebastián;María Isabel Hernández-Alvarez;Jessica Segalés;Eleonora Sorianello

  • The gut microbiota modulates host energy and lipid metabolism in mice.

    Vidya R. Velagapudi;Rahil Hezaveh;Christopher S. Reigstad;Peddinti V. Gopalacharyulu

  • Metabolomics enables precision medicine: "A White Paper, Community Perspective"

    Richard D. Beger;Warwick Dunn;Michael A. Schmidt;Steven S. Gross

  • Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression

    Mika Hilvo;Carsten Denkert;Laura Lehtinen;Berit Müller

  • Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes.

    Matej Orešič;Satu Simell;Marko Sysi-Aho;Kirsti Näntö-Salonen

  • Processing methods for differential analysis of LC/MS profile data.

    Mikko Katajamaa;Matej Orešič

  • PPAR gamma 2 Prevents Lipotoxicity by Controlling Adipose Tissue Expandability and Peripheral Lipid Metabolism

    Gema Medina-Gomez;Sarah L Gray;Laxman Yetukuri;Kenju Shimomura

  • Integration of microRNA miR-122 in hepatic circadian gene expression.

    David Gatfield;Gwendal Le Martelot;Charles E. Vejnar;Daniel Gerlach

  • Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects - A monozygotic twin study

    Kirsi H. Pietiläinen;Kirsi H. Pietiläinen;Marko Sysi-Aho;Aila Rissanen;Tuulikki Seppänen-Laakso

  • Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice

    Xavier Prieur;Crystal Y.L. Mok;Vidya R. Velagapudi;Vanessa Núñez

  • Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease

    Panu K. Luukkonen;Panu K. Luukkonen;You Zhou;Sanja Sädevirta;Sanja Sädevirta;Marja Leivonen

  • Gene-to-metabolite networks for terpenoid indole alkaloid biosynthesis in Catharanthus roseus cells

    Heiko Rischer;Matej Orešič;Tuulikki Seppänen-Laakso;Mikko Katajamaa

  • Pathways to the analysis of microarray data

    R. Keira Curtis;Matej Orešič;Antonio Vidal-Puig

  • Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars

    Panu K Luukkonen;Sanja Sädevirta;You Zhou;Brandon Kayser

Frequent Co-Authors

Tuulia Hyötyläinen
Tuulia Hyötyläinen Örebro University
Tuulikki Seppänen-Laakso
Tuulikki Seppänen-Laakso VTT Technical Research Centre of Finland
Hannele Yki-Järvinen
Hannele Yki-Järvinen University of Helsinki
Antonio Vidal-Puig
Antonio Vidal-Puig University of Cambridge
Jorma Ilonen
Jorma Ilonen University of Turku
Riitta Veijola
Riitta Veijola Oulu University Hospital
Mikael Knip
Mikael Knip University of Helsinki
Jaakko Kaprio
Jaakko Kaprio University of Helsinki
Jorma Toppari
Jorma Toppari University of Turku
Jaana Suvisaari
Jaana Suvisaari Finnish Institute for Health and Welfare (THL)

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