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Fredrik Bäckhed

Fredrik Bäckhed

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Microbiology
Sweden
2026
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Biology and Biochemistry
Sweden
2025

D-Index & Metrics

Microbiology

D-Index
126
Citations
122254
World Ranking
96
National Ranking
3

Medicine

D-Index
127
Citations
122887
World Ranking
2751
National Ranking
51

Research.com Recognitions

  • 2026 - Research.com Microbiology in Sweden Leader Award
  • 2025 - Research.com Biology and Biochemistry in Sweden Leader Award
  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award
  • 2023 - Research.com Medicine in Sweden Leader Award

Overview

Fredrik Bäckhed is affiliated with the University of Gothenburg in Sweden. Their research primarily focuses on the intersection of medicine and biochemistry, genetics, and molecular biology, with particular attention to molecular biology and physiology.

Their work covers a range of topics, including:

  • Gut microbiota and health
  • Diet and metabolism studies
  • Liver disease diagnosis and treatment
  • Metabolomics and mass spectrometry studies
  • Clostridium difficile and Clostridium perfringens research
  • Diet, metabolism, and disease
  • Drug transport and resistance mechanisms

Bäckhed has published in multiple venues with notable frequency, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cell Host & Microbe
  • Cell Reports
  • Cell Metabolism

Among their recent publications are the following papers:

  • Gut microbial metabolites as multi-kingdom intermediates, 2020, Nature Reviews Microbiology
  • The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study, 2020, Cell Metabolism
  • Developmental trajectory of the healthy human gut microbiota during the first 5 years of life, 2021, Cell Host & Microbe
  • Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies, 2023, Nature
  • From Association to Causality: the Role of the Gut Microbiota and Its Functional Products on Host Metabolism, 2020, Molecular Cell

They work frequently with several coauthors, including:

  • Valentina Tremaroli
  • Max Nieuwdorp
  • Stanley L. Hazen
  • Göran Bergström
  • Lisa Olsson

The scientist's research spans multiple subfields within biology and medicine such as surgery, endocrinology, diabetes and metabolism, and epidemiology, reflecting a multidisciplinary approach to studying human health and disease. Their body of work contributes to understanding complex relationships between the gut microbiota and metabolic conditions as well as implications for clinical interventions and therapeutic approaches.

Best Publications

  • The gut microbiota as an environmental factor that regulates fat storage

    Fredrik Bäckhed;Hao Ding;Hao Ding;Ting Wang;Lora V. Hooper

  • Obesity alters gut microbial ecology

    Ruth E. Ley;Fredrik Bäckhed;Peter Turnbaugh;Catherine A. Lozupone

  • Host-Bacterial Mutualism in the Human Intestine

    Fredrik Bäckhed;Ruth E. Ley;Justin L. Sonnenburg;Daniel A. Peterson

  • From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

    Ara Koh;Filipe De Vadder;Petia Kovatcheva-Datchary;Fredrik Bäckhed;Fredrik Bäckhed

  • Functional interactions between the gut microbiota and host metabolism

    Valentina Tremaroli;Fredrik Bäckhed;Fredrik Bäckhed;Fredrik Bäckhed

  • The gut microbiota — masters of host development and physiology

    Felix Sommer;Fredrik Bäckhed;Fredrik Bäckhed;Fredrik Bäckhed

  • Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life.

    Fredrik Bäckhed;Fredrik Bäckhed;Josefine Roswall;Yangqing Peng;Qiang Feng

  • DIET-INDUCED OBESITY IS LINKED TO MARKED BUT REVERSIBLE ALTERATIONS IN THE MOUSE DISTAL GUT MICROBIOME

    Peter J. Turnbaugh;Fredrik Bäckhed;Lucinda Fulton;Jeffrey I. Gordon

  • Gut metagenome in European women with normal, impaired and diabetic glucose control

    Fredrik H. Karlsson;Valentina Tremaroli;Intawat Nookaew;Göran Bergström

  • Mechanisms underlying the resistance to diet-induced obesity in germ-free mice

    Fredrik Bäckhed;Jill K. Manchester;Clay F. Semenkovich;Jeffrey I. Gordon

  • Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism.

    Annika Wahlström;Sama I. Sayin;Hanns-Ulrich Marschall;Fredrik Bäckhed;Fredrik Bäckhed

  • Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy

    Omry Koren;Julia K. Goodrich;Tyler C. Cullender;Aymé Spor

  • Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist.

    Sama I. Sayin;Annika Wahlström;Jenny Felin;Sirkku Jäntti

  • The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease.

    Kassem Makki;Edward C. Deehan;Jens Walter;Fredrik Bäckhed;Fredrik Bäckhed

  • Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

    Filipe De Vadder;Petia Kovatcheva-Datchary;Daisy Goncalves;Jennifer Vinera

  • Diet–microbiota interactions as moderators of human metabolism

    Justin L. Sonnenburg;Fredrik Bäckhed

  • Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

    Buck S. Samuel;Abdullah Shaito;Toshiyuki Motoike;Federico E. Rey

  • Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella

    Petia Kovatcheva-Datchary;Anne Nilsson;Rozita Akrami;Ying Shiuan Lee

  • Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

    Hao Wu;Eduardo Esteve;Eduardo Esteve;Valentina Tremaroli;Muhammad Tanweer Khan

  • Symptomatic atherosclerosis is associated with an altered gut metagenome

    Fredrik H. Karlsson;Frida Fåk;Intawat Nookaew;Valentina Tremaroli

  • The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A.

    F Bäckhed;H Ding;T Wang;LV Hooper

Frequent Co-Authors

Valentina Tremaroli
Valentina Tremaroli University of Gothenburg
Jens Nielsen
Jens Nielsen Chalmers University of Technology
Patrice D. Cani
Patrice D. Cani Université Catholique de Louvain
Nathalie M. Delzenne
Nathalie M. Delzenne Université Catholique de Louvain
Antonio Molinaro
Antonio Molinaro University of Naples Federico II
Jeffrey I. Gordon
Jeffrey I. Gordon Washington University in St. Louis
Hanns-Ulrich Marschall
Hanns-Ulrich Marschall University of Gothenburg
Max Nieuwdorp
Max Nieuwdorp University of Amsterdam
Mathias W. Hornef
Mathias W. Hornef RWTH Aachen University
Matej Orešič
Matej Orešič Örebro University

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