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Medicine
Ireland
2026

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Medicine

D-Index
168
Citations
122728
World Ranking
560
National Ranking
2

Research.com Recognitions

  • 2026 - Research.com Medicine in Ireland Leader Award
  • 2025 - Research.com Medicine in Ireland Leader Award
  • 2023 - Research.com Medicine in Ireland Leader Award
  • 2022 - Research.com Medicine in Ireland Leader Award
  • 2017 - Member of the Royal Irish Academy

Overview

John F. Cryan is affiliated with University College Cork in Ireland. Their research spans several intersecting fields with a primary focus on Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology. Within these areas, Cryan's work frequently addresses subfields such as Molecular Biology, Physiology, Biological Psychiatry, Behavioral Neuroscience, and Social Psychology.

The scientist's main topics of research include gut microbiota and health, tryptophan and brain disorders, diet and metabolism studies, stress responses and cortisol, neuroendocrine regulation and behavior, gastrointestinal motility and disorders, as well as Clostridium difficile and Clostridium perfringens research.

Cryan has contributed to a variety of influential publications, with recent notable papers including:

  • The Microbiota-Gut-Brain Axis: From Motility to Mood (2021, Gastroenterology)
  • Diet and depression: exploring the biological mechanisms of action (2020, Molecular Psychiatry)
  • The blood-brain barrier in aging and neurodegeneration (2022, Molecular Psychiatry)
  • Short chain fatty acids: Microbial metabolites for gut-brain axis signalling (2022, Molecular and Cellular Endocrinology)
  • Stress resilience during the coronavirus pandemic (2020, European Neuropsychopharmacology)

The venues where Cryan frequently publishes include Neuroscience Applied, Brain Behavior and Immunity, bioRxiv (Cold Spring Harbor Laboratory), Trends in Neurosciences, and Molecular Psychiatry.

They regularly collaborate with a group of co-authors who have contributed significantly to Cryan's research output. Frequent collaborators include Gerard Clarke, Timothy G. Dinan, Thomaz F. S. Bastiaanssen, Catherine Stanton, and Gerard M. Moloney.

John F. Cryan was awarded membership to the Royal Irish Academy in 2017, which signifies recognition within the scholarly community.

Best Publications

  • Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

    John F. Cryan;Timothy G. Dinan

  • The Microbiota-Gut-Brain Axis

    John F Cryan;Kenneth J O'Riordan;Caitlin S M Cowan;Kiran V Sandhu

  • Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve.

    Javier A. Bravo;Paul Forsythe;Marianne V. Chew;Emily Escaravage

  • Serotonin, tryptophan metabolism and the brain-gut-microbiome axis.

    S.M. O’Mahony;G. Clarke;Y.E. Borre;T.G. Dinan

  • The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

    G Clarke;S Grenham;P Scully;P Fitzgerald

  • Assessing antidepressant activity in rodents: recent developments and future needs

    John F. Cryan;Athina Markou;Irwin Lucki

  • The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice.

    John F. Cryan;Cedric Mombereau;Annick Vassout

  • Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat.

    John R Kelly;Yuliya Borre;Ciaran O' Brien;Ciaran O' Brien;Elaine Patterson;Elaine Patterson

  • The ascent of mouse: advances in modelling human depression and anxiety.

    John F. Cryan;John F. Cryan;Andrew Holmes

  • Minireview: Gut Microbiota: The Neglected Endocrine Organ

    Gerard Clarke;Roman M. Stilling;Paul J. Kennedy;Catherine Stanton;Catherine Stanton

  • Psychobiotics: a novel class of psychotropic.

    Timothy G. Dinan;Catherine Stanton;John F. Cryan

  • Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test.

    John F. Cryan;Rita J. Valentino;Irwin Lucki

  • Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses.

    Siobhain M. O'Mahony;Julian R. Marchesi;Julian R. Marchesi;Paul Scully;Caroline Codling

  • Gut microbes and the brain: paradigm shift in neuroscience.

    Emeran A. Mayer;Rob Knight;Sarkis K. Mazmanian;John F. Cryan

  • Microbiota and neurodevelopmental windows: implications for brain disorders

    Yuliya E. Borre;Gerard W. O’Keeffe;Gerard Clarke;Catherine Stanton

  • Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression.

    L. Desbonnet;L. Garrett;G. Clarke;B. Kiely

  • Stress & the gut-brain axis: Regulation by the microbiome

    Jane A. Foster;Linda Rinaman;John F. Cryan

  • Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

    John R. Kelly;Paul J. Kennedy;John F. Cryan;Timothy G. Dinan

  • Brain–Gut–Microbe Communication in Health and Disease

    Sue Grenham;Gerard Clarke;John F. Cryan;Timothy G. Dinan

  • The microbiome-gut-brain axis: from bowel to behavior.

    J. F. Cryan;S. M. O’Mahony

Frequent Co-Authors

Timothy G. Dinan
Timothy G. Dinan University College Cork
Gerard Clarke
Gerard Clarke University College Cork
Catherine Stanton
Catherine Stanton Teagasc - The Irish Agriculture and Food Development Authority
Paul D. Cotter
Paul D. Cotter University College Cork
Eamonn Martin Quigley
Eamonn Martin Quigley Cornell University
Fergus Shanahan
Fergus Shanahan National University of Ireland
R. Paul Ross
R. Paul Ross University College Cork
Yvonne M. Nolan
Yvonne M. Nolan University College Cork
Klemens Kaupmann
Klemens Kaupmann Novartis (Switzerland)
Orla O'Sullivan
Orla O'Sullivan Teagasc - The Irish Agriculture and Food Development Authority

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