World's Best Scientists 2026 revealed!
Nicolas Singewald

Nicolas Singewald

D-Index & Metrics

Neuroscience

D-Index
76
Citations
15993
World Ranking
1962
National Ranking
15

Overview

Nicolas Singewald is affiliated with the University of Innsbruck in Austria. Their research encompasses a blend of materials science and neuroscience, with particular emphasis on crystallization and solubility studies as well as the neurobiological mechanisms underlying stress and anxiety disorders.

Their academic contributions include publications across fields such as materials chemistry, behavioral neuroscience, cellular and molecular neuroscience, cognitive neuroscience, and biological psychiatry. Singewald's most frequent topics of work span:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Stress Responses and Cortisol
  • Tryptophan and Brain Disorders
  • Memory and Neural Mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neuroendocrine Regulation and Behavior

Their research findings have been disseminated through various publication venues, with the most frequent being The Cambridge Structural Database, where they have contributed to 31 publications. Other venues include Translational Psychiatry, Biomolecules, Neuroscience Applied, and Nature Communications.

Recent papers authored or co-authored by Singewald reflect a focus on anxiety, trauma, and neural mechanisms related to stress and fear. Notable recent works include:

  • "Alleviating anxiety and taming trauma: Novel pharmacotherapeutics for anxiety disorders and posttraumatic stress disorder," 2023, Neuropharmacology
  • "Brain-derived neurotrophic factor expression in serotonergic neurons improves stress resilience and promotes adult hippocampal neurogenesis," 2022, Progress in Neurobiology
  • "Central amygdala micro-circuits mediate fear extinction," 2021, Nature Communications
  • "Neuroinflammatory alterations in trait anxiety: modulatory effects of minocycline," 2020, Translational Psychiatry
  • "Microglial ablation in rats disrupts the circadian system," 2020, The FASEB Journal

Collaboration plays a significant role in Singewald's work, demonstrated by frequent co-authors who have collectively contributed to numerous publications. Collaborators include Simone B. Sartori, Karl Ebner, Predrag Kalaba, Vladimir Dragačević, and Johann Leban.

Best Publications

  • Neuronal circuits of fear extinction.

    Cyril Herry;Francesco Ferraguti;Nicolas Singewald;Johannes J. Letzkus

  • Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders.

    N. Singewald;C. Schmuckermair;N. Whittle;A. Holmes

  • The role of substance P in stress and anxiety responses

    K. Ebner;N. Singewald

  • Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs.

    Nicolas Singewald;Peter Salchner;Trevor Sharp

  • Impaired Fear Extinction Learning and Cortico-Amygdala Circuit Abnormalities in a Common Genetic Mouse Strain

    Kathryn Hefner;Nigel Whittle;Jaynann Juhasz;Maxine Norcross

  • Substance P in the medial amygdala: Emotional stress-sensitive release and modulation of anxiety-related behavior in rats

    Karl Ebner;Nadia M. Rupniak;Alois Saria;Nicolas Singewald

  • Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment.

    S.B. Sartori;N. Whittle;A. Hetzenauer;N. Singewald

  • Prefrontal inputs to the amygdala instruct fear extinction memory formation.

    Olena Bukalo;Courtney R. Pinard;Shana Silverstein;Shana Silverstein;Christina Brehm

  • Isoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca 2+ channels.

    Martina J. Sinnegger-Brauns;Alfred Hetzenauer;Irene G. Huber;Erik Renström

  • Release of neurotransmitters in the locus coeruleus

    Nicolas Singewald;Athineos Philippu

  • Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders.

    Simone B. Sartori;Nicolas Singewald

  • Release of oxytocin in the rat central amygdala modulates stress-coping behavior and the release of excitatory amino acids

    Karl Ebner;Oliver J Bosch;Simone A Krömer;Nicolas Singewald

  • Single dose of l-dopa makes extinction memories context-independent and prevents the return of fear

    Jan Haaker;Stefano Gaburro;Anupam Sah;Nina Gartmann

  • Candidate genes of anxiety-related behavior in HAB/LAB rats and mice: Focus on vasopressin and glyoxalase-I

    Rainer Landgraf;Melanie S Kessler;Mirjam Bunck;Chris Murgatroyd

  • Reduced anxiety and improved stress coping ability in mice lacking NPY‐Y2 receptors

    Alexandra Tschenett;Nicolas Singewald;Mirjana Carli;Claudia Balducci

  • Acute transcranial magnetic stimulation of frontal brain regions selectively modulates the release of vasopressin, biogenic amines and amino acids in the rat brain

    Martin E. Keck;Inge Sillaber;Karl Ebner;Tobias Welt

  • Role of voltage-gated L-type Ca2+ channel isoforms for brain function.

    J. Striessnig;A. Koschak;M.J. Sinnegger-Brauns;A. Hetzenauer

  • Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug

    Julia Marschallinger;Iris Schäffner;Barbara Klein;Renate Gelfert

  • Magnesium-deficient diet alters depression- and anxiety-related behavior in mice—influence of desipramine and Hypericum perforatum extract

    Nicolas Singewald;Catrin Sinner;Alfred Hetzenauer;Simone B. Sartori

  • Prodynorphin-derived peptides are critical modulators of anxiety and regulate neurochemistry and corticosterone.

    Walter Wittmann;Eduard Schunk;Iris Rosskothen;Stefano Gaburro

  • The modulatory role of the lateral septum on neuroendocrine and behavioral stress responses.

    Georg M Singewald;Alesja Rjabokon;Nicolas Singewald;Karl Ebner

Frequent Co-Authors

Athineos Philippu
Athineos Philippu University of Innsbruck
Francesco Ferraguti
Francesco Ferraguti Innsbruck Medical University
Mario Engelmann
Mario Engelmann Otto-von-Guericke University Magdeburg
Günther Sperk
Günther Sperk Innsbruck Medical University
Carsten T. Wotjak
Carsten T. Wotjak Max Planck Society
Hans-Christian Pape
Hans-Christian Pape University of Münster
Andreas Lüthi
Andreas Lüthi Friedrich Miescher Institute
Christoph Schwarzer
Christoph Schwarzer Innsbruck Medical University
Timothy W. Bredy
Timothy W. Bredy University of Queensland
Jan M. Deussing
Jan M. Deussing Max Planck Society

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring neuroscience can open doors to a variety of lucrative professions. If you’re drawn to exciting opportunities, consider reviewing the highest paying jobs in the field—including in research, biotech, and clinical roles.

For those interested in flexible learning, there are many online colleges that accept financial aid, making a neuroscience or related degree more budget-friendly. Some options even feature accelerated programs and transfer policies to help you finish faster.

Specialized skills can also boost your resume. Many students start with certificates online in areas like data analysis, neuroimaging, or medical technology, which provide practical knowledge valued by employers.

If efficiency and affordability are priorities, you might want to explore the cheapest easiest online degree paths related to neuroscience. These options can help you enter the workforce or pursue advanced study more quickly and with less student debt.

Best Scientists Citing Nicolas Singewald

Trending Scientists