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Neuroscience

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Research.com Recognitions

  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Marie-Françoise Chesselet is affiliated with the University of California, Los Angeles in the United States. Their research spans multiple disciplines within medicine, neuroscience, and biochemistry, genetics, and molecular biology, with an emphasis on neurological diseases and neurodegenerative disorders.

The primary fields of study for this scientist include Medicine, Neuroscience, and Biochemistry, Genetics, and Molecular Biology. Their work covers subfields such as Neurology, Physiology, Genetics, Molecular Biology, and Cellular and Molecular Neuroscience.

The main topics of Marie-Françoise Chesselet's research include:

  • Alzheimer's disease research and treatments
  • Parkinson's Disease mechanisms and treatments
  • Neurological diseases and metabolism
  • Neurological disorders and treatments
  • Amyotrophic Lateral Sclerosis research
  • Genetics and neurodevelopmental disorders
  • Dementia and cognitive impairment research

Frequent co-authors collaborating with this researcher are:

  • David W. Fardo
  • James D. Bowen
  • Paul K. Crane
  • James R. Burke
  • Liana G. Apostolova

The scientist has published in a range of venues, with frequent contributions appearing in:

  • Movement Disorders
  • Neurobiology of Disease
  • Journal of Neuropathology & Experimental Neurology
  • Brain
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent publications by Marie-Françoise Chesselet include:

  • "Defining the Riddle in Order to Solve It: There Is More Than One "Parkinson's Disease"" (2023) in Movement Disorders
  • "Alpha-synuclein pathology, microgliosis, and parvalbumin neuron loss in the amygdala associated with enhanced fear in the Thy1-aSyn model of Parkinson's disease" (2021) in Neurobiology of Disease
  • "LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry" (2023) in Journal of Neuropathology & Experimental Neurology
  • "Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK, GRB14, and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium" (2023) in bioRxiv (Cold Spring Harbor Laboratory)
  • "Amyloid-β predominant Alzheimer's disease neuropathologic change" (2024) in Brain

Marie-Françoise Chesselet was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2010, reflecting a professional acknowledgment in the scientific community.

Best Publications

  • Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

    Timothy R. Sampson;Justine W. Debelius;Taren Thron;Stefan Janssen

  • Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK, GRB14, and KIAA0825 as novel risk loci for Alzheimer disease: the Alzheimer Disease Genetics Consortium

    Unknown

  • Parkin-deficient Mice Exhibit Nigrostriatal Deficits but Not Loss of Dopaminergic Neurons

    Matthew S. Goldberg;Sheila M. Fleming;James J. Palacino;Carlos Cepeda

  • Coordinated Expression of Dopamine Receptors in Neostriatal Medium Spiny Neurons

    D. James Surmeier;Wen Jie Song;Zhen Yan

  • Mitochondrial dysfunction and oxidative stress in Parkinson's disease.

    Sudhakar Raja Subramaniam;Marie-Francoise Chesselet

  • Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.

    Liliana B. Menalled;Jessica D. Sison;Ioannis Dragatsis;Scott Zeitlin

  • Early and Progressive Sensorimotor Anomalies in Mice Overexpressing Wild-Type Human α-Synuclein

    Sheila M. Fleming;Jonathan Salcedo;Pierre-Olivier Fernagut;Edward Rockenstein

  • Synchronous Neuronal Activity Is a Signal for Axonal Sprouting after Cortical Lesions in the Adult

    S. Thomas Carmichael;Marie-Françoise Chesselet

  • Mouse models of Huntington's disease.

    Liliana B Menalled;Marie-Françoise Chesselet

  • Enhanced sensitivity to N‐methyl‐D‐aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease

    Michael S. Levine;Gloria J. Klapstein;Ahrin Koppel;Ehud Gruen

  • Direct Regulation of Adult Brain Function by the Male-Specific Factor SRY

    Phoebe Dewing;Charleston W K Chiang;Kevin Sinchak;Helena Sim

  • A Progressive Mouse Model of Parkinson’s Disease: The Thy1-aSyn (“Line 61”) Mice

    Marie-Francoise Chesselet;Franziska Richter;Chunni Zhu;Iddo Magen

  • Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice.

    Gloria J. Klapstein;Robin S. Fisher;Hadi Zanjani;Carlos Cepeda

  • Expression of Mu opioid receptor mRNA in rat brain: An in situ hybridization study at the single cell level

    Jill M. Delfs;Haeyoung Kong;Anton Mestek;Yan Chen

  • Animal models of Parkinson's disease progression.

    Gloria E. Meredith;Patricia K. Sonsalla;Marie-Francoise Chesselet

  • Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone

    Sheila M Fleming;Chunni Zhu;Pierre-Olivier Fernagut;Arpesh Mehta

  • Neurons express hemoglobin α‐ and β‐chains in rat and human brains

    Franziska Richter;Bernhard H. Meurers;Chunni Zhu;Vera P. Medvedeva

  • Apoptosis in Huntington's disease.

    Miriam A Hickey;Marie Françoise Chesselet

  • Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice

    Liliana B. Menalled;Jessica D. Sison;Ying Wu;Melisa Olivieri

  • Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein

    Melanie B. Watson;Franziska Richter;Soo Kyung Lee;Lauryn Gabby

  • Olfactory deficits in mice overexpressing human wildtype α‐synuclein

    Sheila M. Fleming;Nicole A. Tetreault;Caitlin K. Mulligan;Ché B. Hutson

  • Comparative distribution of mRNAs for glutamic acid decarboxylase, tyrosine hydroxylase, and tachykinins in the basal ganglia: an in situ hybridization study in the rodent brain.

    Marie-Francoise Chesselet;Linda Weiss;Carol Wuenschell;Allan J. Tobin

Frequent Co-Authors

Sheila M. Fleming
Sheila M. Fleming University of Cincinnati
Michael S. Levine
Michael S. Levine Princeton University
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Pierre-Olivier Fernagut
Pierre-Olivier Fernagut University of Poitiers
Scott Zeitlin
Scott Zeitlin University of Virginia
Carlos Cepeda
Carlos Cepeda University of California, Los Angeles
Nigel T. Maidment
Nigel T. Maidment University of California, Los Angeles
Philippe De Deurwaerdère
Philippe De Deurwaerdère University of Bordeaux
Yvette Taché
Yvette Taché University of California, Los Angeles
Vivian Hook
Vivian Hook University of California, San Diego

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