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Pierre-Olivier Fernagut

Pierre-Olivier Fernagut

D-Index & Metrics

Neuroscience

D-Index
45
Citations
8303
World Ranking
6899
National Ranking
303

Overview

Pierre-Olivier Fernagut is affiliated with the University of Poitiers in France. Their research primarily spans Medicine and Neuroscience, with a focus on Neurology and Cellular and Molecular Neuroscience among other subfields. The main topics of their work include Parkinson's Disease Mechanisms and Treatments, Neurological disorders and treatments, Nuclear Receptors and Signaling, Nerve injury and regeneration, Autism Spectrum Disorder Research, Botulinum Toxin and Related Neurological Disorders, and RNA regulation and disease.

The scientist has contributed notably to several publication venues. Frequent venues include:

  • npj Parkinson s Disease
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuropathology and Applied Neurobiology
  • Biomedicines
  • Movement Disorders

Among recent papers authored or co-authored by Pierre-Olivier Fernagut are:

  • Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction, 2020, Brain
  • Impaired brain insulin signalling in Parkinson's disease, 2021, Neuropathology and Applied Neurobiology
  • Mass spectrometry imaging identifies abnormally elevated brain l -DOPA levels and extrastriatal monoaminergic dysregulation in l -DOPA-induced dyskinesia, 2021, Science Advances
  • Neuropsychiatric and Cognitive Deficits in Parkinson's Disease and Their Modeling in Rodents, 2021, Biomedicines
  • L-DOPA regulates α-synuclein accumulation in experimental parkinsonism, 2020, Neuropathology and Applied Neurobiology

Their frequent co-authors include:

  • Mélina Decourt
  • Erwan Bézard
  • Marianne Benoit-Marand
  • Wassilios G. Meissner
  • Maureen Francheteau

The research carried out by Pierre-Olivier Fernagut largely addresses mechanisms and treatments pertaining to Parkinson's disease, reflected in both the publication venues and specific paper topics. Their work integrates molecular and cellular neuroscience approaches to explore neurodegenerative diseases and associated cognitive and psychiatric deficits, as well as exploring dysfunction at the level of brain insulin signaling and synuclein protein regulation.

Their scholarly output demonstrates multidisciplinary engagement with neurology, physiology, molecular biology, and the neurobiological underpinnings of neurological disorders and therapeutic interventions.

Best Publications

  • Lewy body extracts from Parkinson disease brains trigger α‐synuclein pathology and neurodegeneration in mice and monkeys

    Ariadna Recasens;Benjamin Dehay;Jordi Bové;Iria Carballo-Carbajal

  • Early and Progressive Sensorimotor Anomalies in Mice Overexpressing Wild-Type Human α-Synuclein

    Sheila M. Fleming;Jonathan Salcedo;Pierre-Olivier Fernagut;Edward Rockenstein

  • Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease.

    Matthieu F. Bastide;Wassilios G. Meissner;Barbara Picconi;Stefania Fasano

  • Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders

    Valerie Voon;Pierre-Olivier Fernagut;Jeff Wickens;Christelle Baunez

  • Direct Regulation of Adult Brain Function by the Male-Specific Factor SRY

    Phoebe Dewing;Charleston W K Chiang;Kevin Sinchak;Helena Sim

  • Impulse control disorders and levodopa-induced dyskinesias in Parkinson's disease: an update.

    Valerie Voon;Valerie Voon;T Celeste Napier;Michael J Frank;Veronique Sgambato-Faure;Veronique Sgambato-Faure

  • Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone

    Sheila M Fleming;Chunni Zhu;Pierre-Olivier Fernagut;Arpesh Mehta

  • A simple method to measure stride length as an index of nigrostriatal dysfunction in mice

    Pierre O Fernagut;Elsa Diguet;Bertrand Labattu;François Tison

  • Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: targets for disease modification?

    Fares Bassil;Pierre-Olivier Fernagut;Erwan Bezard;Wassilios G. Meissner

  • Behavioral and histopathological consequences of paraquat intoxication in mice: Effects of α‐synuclein over‐expression

    P.O. Fernagut;C.B. Hutson;S.M. Fleming;N.A. Tetreaut

  • Alpha-synuclein and transgenic mouse models.

    Pierre-Olivier Fernagut;Marie-Françoise Chesselet

  • Genetic Mouse Models of Parkinsonism: Strengths and Limitations

    Sheila M. Fleming;Pierre-Olivier Fernagut;Marie-Françoise Chesselet

  • Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease.

    Elsa Diguet;Pierre Olivier Fernagut;Pierre Olivier Fernagut;Xing Wei;Yansheng Du

  • Subacute systemic 3-nitropropionic acid intoxication induces a distinct motor disorder in adult C57Bl/6 mice: behavioural and histopathological characterisation.

    P.O. Fernagut;E. Diguet;N. Stefanova;M. Biran

  • Dopamine and addiction: what have we learned from 40 years of research.

    Marcello Solinas;Pauline Belujon;Pierre Olivier Fernagut;Mohamed Jaber

  • Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression

    Mathieu Bourdenx;Sandra Dovero;Michel Engeln;Simone Bido

  • Protein aggregation in the aging retina.

    François Leger;Pierre-Olivier Fernagut;Marie-Hélène Canron;Sandy Léoni

  • Sex-dependent behavioral deficits and neuropathology in a maternal immune activation model of autism.

    Obelia Haida;Tareq Al Sagheer;Anais Balbous;Maureen Francheteau

  • Variable effects of chronic subcutaneous administration of rotenone on striatal histology.

    Chunni Zhu;Patrick Vourc'h;Pierre‐Olivier Fernagut;Sheila M. Fleming

  • Motor behaviour deficits and their histopathological and functional correlates in the nigrostriatal system of dopamine transporter knockout mice.

    P.-O Fernagut;S Chalon;E Diguet;D Guilloteau

  • Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome

    Arthur P. Chou;Nigel Maidment;Rebecka Klintenberg;John E. Casida

Frequent Co-Authors

Wassilios G. Meissner
Wassilios G. Meissner University of Bordeaux
Mohamed Jaber
Mohamed Jaber University of Poitiers
François Tison
François Tison University of Bordeaux
Marie-Françoise Chesselet
Marie-Françoise Chesselet University of California, Los Angeles
Sheila M. Fleming
Sheila M. Fleming University of Cincinnati
Qin Li
Qin Li Peking Union Medical College Hospital
François Georges
François Georges University of Bordeaux
Christian E. Gross
Christian E. Gross University of Bordeaux
Serge H. Ahmed
Serge H. Ahmed University of Bordeaux
Olivier Rascol
Olivier Rascol Federal University of Toulouse Midi-Pyrénées

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