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Biology and Biochemistry

D-Index
54
Citations
14113
World Ranking
15435
National Ranking
618

Overview

Sophie Rousseaux is affiliated with Joseph Fourier University in France and has contributed extensively to research in biochemistry, genetics, and molecular biology, with additional work in the field of medicine. Their scholarly output includes a focus on molecular biology, hematology, cancer research, immunology, and pulmonary and respiratory medicine.

The main research themes covered by Sophie Rousseaux include:

  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Protein Degradation and Inhibitors
  • Ubiquitin and proteasome pathways
  • Histone Deacetylase Inhibitors Research
  • Cancer-related gene regulation
  • Genomics and Chromatin Dynamics

Their recent notable papers are:

  • "DEN-Induced Rat Model Reproduces Key Features of Human Hepatocellular Carcinoma," 2021, published in Cancers
  • "Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution," 2021, published in Cell Reports
  • "Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions," 2020, published in BMC Medicine
  • "Pregnancy exposure to synthetic phenols and placental DNA methylation - An epigenome-wide association study in male infants from the EDEN cohort," 2021, published in Environmental Pollution
  • "The combined detection of Amphiregulin, Cyclin A1 and DDX20/Gemin3 expression predicts aggressive forms of oral squamous cell carcinoma," 2021, published in British Journal of Cancer

Frequently publishing in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cancers, Cell Reports, Cell Discovery, and Cells, Rousseaux's work spans multiple high-impact journals in the fields of molecular biology and cancer research.

Collaborations have been a significant component of their research activity. Frequent coauthors include:

  • Saadi Khochbin
  • Florent Chuffart
  • Ekaterina Bourov\ufeffa-Flin
  • Anne-Laure Vitte
  • Sophie Barral

This network of coauthors reflects an extensive engagement in multi-disciplinary and collaborative scientific projects centered on molecular genetics and cancer biology.

Best Publications

  • Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

    Minjia Tan;Hao Luo;Sangkyu Lee;Fulai Jin

  • Dynamic Molecular Combing: Stretching the Whole Human Genome for High-Resolution Studies

    Xavier Michalet;Rosemary Ekong;Françoise Fougerousse;Sophie Rousseaux

  • Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally

    Yu Zhang;So Hee Kwon;Teppei Yamaguchi;Fabien Cubizolles

  • Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

    Jeanne Morinière;Sophie Rousseaux;Ulrich Steuerwald;Montserrat Soler-López

  • Ectopic Activation of Germline and Placental Genes Identifies Aggressive Metastasis-Prone Lung Cancers

    Sophie Rousseaux;Alexandra Debernardi;Baptiste Jacquiau;Anne Laure Vitte

  • Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark

    Lunzhi Dai;Chao Peng;Emilie Montellier;Zhike Lu

  • Identification of Components of the Murine Histone Deacetylase 6 Complex: Link between Acetylation and Ubiquitination Signaling Pathways

    Daphnée Seigneurin-Berny;André Verdel;Sandrine Curtet;Claudie Lemercier

  • The role of histones in chromatin remodelling during mammalian spermiogenesis.

    Jérôme Govin;Cécile Caron;Cécile Lestrat;Sophie Rousseaux

  • Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis.

    Jérôme Govin;Emmanuelle Escoffier;Emmanuelle Escoffier;Sophie Rousseaux;Sophie Rousseaux;Lauriane Kuhn;Lauriane Kuhn;Lauriane Kuhn

  • Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein.

    Christophe Pivot-Pajot;Cécile Caron;Jérôme Govin;Alexandre Vion

  • Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility.

    Klaus Dieterich;Ricardo Soto Rifo;Ricardo Soto Rifo;Anne Karen Faure;Anne Karen Faure;Sylviane Hennebicq;Sylviane Hennebicq

  • Active maintenance of mHDA2/mHDAC6 histone-deacetylase in the cytoplasm

    André Verdel;Sandrine Curtet;Marie-Paule Brocard;Sophie Rousseaux

  • Regulated hyperacetylation of core histones during mouse spermatogenesis: involvement of histone deacetylases.

    Mira Hazzouri;Christophe Pivot-Pajot;Anne-Karen Faure;Yves Usson

  • Bromodomain‐dependent stage‐specific male genome programming by Brdt

    Jonathan Gaucher;Fayçal Boussouar;Emilie Montellier;Sandrine Curtet

  • Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters

    Afsaneh Goudarzi;Di Zhang;He Huang;Sophie Barral

  • Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B

    Emilie Montellier;Fayçal Boussouar;Sophie Rousseaux;Kai Zhang

  • Differential histone modifications mark mouse imprinting control regions during spermatogenesis.

    Katia Delaval;Jérôme Govin;Jérôme Govin;Frédérique Cerqueira;Sophie Rousseaux;Sophie Rousseaux

  • Establishment of male-specific epigenetic information.

    Sophie Rousseaux;Cécile Caron;Jérôme Govin;Cécile Lestrat

  • Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers.

    C. Caron;C. Lestrat;S. Marsal;E. Escoffier

  • Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains

    Nicolas Reynoird;Brian E Schwartz;Manuela Delvecchio;Karin Sadoul

Frequent Co-Authors

Saadi Khochbin
Saadi Khochbin Grenoble Alpes University
Myriam Ferro
Myriam Ferro Grenoble Alpes University
Jérôme Garin
Jérôme Garin CEA Grenoble
Lauriane Kuhn
Lauriane Kuhn Centre national de la recherche scientifique, CNRS
Yingming Zhao
Yingming Zhao University of Chicago
Christian Brambilla
Christian Brambilla Centre national de la recherche scientifique, CNRS
Elisabeth Brambilla
Elisabeth Brambilla Grenoble Alpes University
Pierre Hainaut
Pierre Hainaut Grenoble Alpes University
robert feil
robert feil Centre national de la recherche scientifique, CNRS
Bing Ren
Bing Ren New York Genome Center

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