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Christophe Arnoult

Christophe Arnoult

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
10055
World Ranking
14544
National Ranking
560

Overview

Christophe Arnoult is affiliated with Grenoble Alpes University in France. The research conducted by this scientist primarily falls within the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on subfields such as Reproductive Medicine, Genetics, Public Health, Environmental and Occupational Health, Molecular Biology, and Pediatrics, Perinatology and Child Health.

The main topics of research associated with Christophe Arnoult cover diverse areas related to reproductive health and genetic conditions. These topics include:

  • Sperm and Testicular Function
  • Reproductive Biology and Fertility
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Genetic and Kidney Cyst Diseases
  • Prenatal Screening and Diagnostics
  • Renal and related cancers
  • Trypanosoma species research and implications

Recent papers authored or co-authored by Christophe Arnoult illustrate the scope and direction of their research. These papers include:

  • The genetic architecture of morphological abnormalities of the sperm tail, published in 2020 in Human Genetics
  • Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility, published in 2020 in The American Journal of Human Genetics
  • Whole-exome sequencing improves the diagnosis and care of men with non-obstructive azoospermia, published in 2022 in The American Journal of Human Genetics
  • Diversity of RNA-Binding Proteins Modulating Post-Transcriptional Regulation of Protein Expression in the Maturing Mammalian Oocyte, published in 2020 in Cells
  • Paternal epigenetics: Mammalian sperm provide much more than DNA at fertilization, published in 2020 in Molecular and Cellular Endocrinology

Christophe Arnoult has collaborated frequently with several researchers, indicating a network of co-authors that frequently work together. These include:

  • Pierre F. Ray
  • Zine-Eddine Kherraf
  • Charles Coutton
  • Caroline Cazin
  • Guillaume Martinez

The scientist's work has been published in a variety of venues, with repeated publications in specific journals. The prominent publication venues where Christophe Arnoult has contributed multiple articles are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Human Genetics
  • International Journal of Molecular Sciences
  • Clinical Genetics
  • Human Reproduction

Best Publications

  • Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella.

    Mariem Ben Khelifa;Mariem Ben Khelifa;Mariem Ben Khelifa;Charles Coutton;Charles Coutton;Raoudha Zouari;Thomas Karaouzène;Thomas Karaouzène

  • Teratozoospermia: spotlight on the main genetic actors in the human

    Charles Coutton;Jessica Escoffier;Guillaume Martinez;Christophe Arnoult

  • Activation of mouse sperm T-type Ca2+ channels by adhesion to the egg zona pellucida

    Christophe Arnoult;Richard A. Cardullo;Jose R. Lemos;Harvey M. Florman

  • Control of the low voltage-activated calcium channel of mouse sperm by egg ZP3 and by membrane hyperpolarization during capacitation

    Christophe Arnoult;Imrana G. Kazam;Pablo E. Visconti;Gregory S. Kopf

  • Ca2+ Entry through Store-operated Channels in Mouse Sperm Is Initiated by Egg ZP3 and Drives the Acrosome Reaction

    Christine M.B. O'Toole;Christophe Arnoult;Alberto Darszon;Richard A. Steinhardt

  • The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation.

    Alexa S. Green;Alexa S. Green;Nicolas Chapuis;Nicolas Chapuis;Thiago Trovati Maciel;Lise Willems;Lise Willems

  • A Perspective on the Control of Mammalian Fertilization by Egg-Activated Ion Channels in Sperm: A Tale of Two Channels

    Harvey M. Florman;Christophe Arnoult;Imrana G. Kazam;Chongqing Li

  • Role of TLR9 in Anti-Nucleosome and Anti-DNA Antibody Production in lpr Mutation-Induced Murine Lupus

    Aurelia Lartigue;Philippe Courville;Isabelle Auquit;Arnaud François

  • A Recurrent Deletion of DPY19L2 Causes Infertility in Man by Blocking Sperm Head Elongation and Acrosome Formation

    Radu Harbuz;Radu Harbuz;Raoudha Zouari;Virginie Pierre;Virginie Pierre;Mariem Ben Khelifa;Mariem Ben Khelifa

  • Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human

    Charles Coutton;Alexandra S. Vargas;Amir Amiri-Yekta;Amir Amiri-Yekta;Zine-Eddine Kherraf

  • The genetic architecture of morphological abnormalities of the sperm tail.

    Aminata Touré;Guillaume Martinez;Zine-Eddine Kherraf;Caroline Cazin

  • Critical Role of TLR2 and TLR4 in Autoantibody Production and Glomerulonephritis in lpr Mutation-Induced Mouse Lupus

    Aurelia Lartigue;Natacha Colliou;Sébastien Calbo;Arnault François

  • Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus

    Virginie Pierre;Virginie Pierre;Guillaume Martinez;Guillaume Martinez;Charles Coutton;Charles Coutton;Julie Delaroche;Julie Delaroche

  • ZP3-dependent activation of sperm cation channels regulates acrosomal secretion during mammalian fertilization.

    Christophe Arnoult;Yang Zeng;Harvey M. Florman

  • In vivo pathogenicity of IgG from patients with anti-SRP or anti-HMGCR autoantibodies in immune-mediated necrotising myopathy.

    Cécile Bergua;Hélène Chiavelli;Yves Allenbach;Louiza Arouche-Delaperche

  • Genetic abnormalities leading to qualitative defects of sperm morphology or function.

    P.F. Ray;P.F. Ray;A. Toure;A. Toure;A. Toure;C. Metzler-Guillemain;M.J. Mitchell

  • Absence of CFAP69 Causes Male Infertility due to Multiple Morphological Abnormalities of the Flagella in Human and Mouse.

    Frederick N. Dong;Amir Amiri-Yekta;Amir Amiri-Yekta;Guillaume Martinez;Antoine Saut

  • Pharmacological properties of the T-type Ca2+ current of mouse spermatogenic cells.

    Christophe Arnoult;Michel Villaz;Harvey M. Florman

  • Bi-allelic Mutations in ARMC2 Lead to Severe Astheno-Teratozoospermia Due to Sperm Flagellum Malformations in Humans and Mice

    Charles Coutton;Charles Coutton;Guillaume Martinez;Guillaume Martinez;Zine-Eddine Kherraf;Zine-Eddine Kherraf;Amir Amiri-Yekta;Amir Amiri-Yekta;Amir Amiri-Yekta

  • Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility

    Chunyu Liu;Haruhiko Miyata;Yang Gao;Yanwei Sha

Frequent Co-Authors

Pierre F. Ray
Pierre F. Ray Grenoble Alpes University
Michel De Waard
Michel De Waard University of Nantes
Gérard Lambeau
Gérard Lambeau Centre national de la recherche scientifique, CNRS
Alain Schmitt
Alain Schmitt Institut Cochin
Joël Lunardi
Joël Lunardi Grenoble Alpes University
Serge Nef
Serge Nef University of Geneva
Annie Andrieux
Annie Andrieux Grenoble Alpes University
François Tron
François Tron University of Rouen
Olivier Boyer
Olivier Boyer University of Rouen

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