Christophe Arnoult spends much of his time researching Genetics, Cell biology, Sperm, Acrosome and Male infertility. His Genetics study is mostly concerned with Globozoospermia and Mutation. His study in Cell biology is interdisciplinary in nature, drawing from both Molecular biology, Calcium-binding protein and T-type calcium channel, Voltage-dependent calcium channel.
He combines subjects such as Sperm-Ovum Interactions, Internal medicine and Endocrinology with his study of Sperm. His Acrosome course of study focuses on Zona pellucida and Acrosome reaction, Transmembrane protein and Nucleus. His studies deal with areas such as Sperm motility, Genetic linkage and Reproductive technology as well as Male infertility.
Sperm, Cell biology, Genetics, Male infertility and Sperm motility are his primary areas of study. His Sperm research is multidisciplinary, incorporating perspectives in Embryo and Human fertilization. His Cell biology study integrates concerns from other disciplines, such as Endocrinology, Internal medicine and Voltage-dependent calcium channel.
The study incorporates disciplines such as Phenotype, Flagellum and Spermatogenesis in addition to Male infertility. In his study, Endogeny and Mutant is strongly linked to Phospholipase A2, which falls under the umbrella field of Acrosome reaction. His research in Infertility intersects with topics in Gamete and Bioinformatics.
Christophe Arnoult spends much of his time researching Sperm, Cell biology, Genetics, Male infertility and Sperm flagellum. His studies in Sperm integrate themes in fields like Flagellum, Intracytoplasmic sperm injection and Spermatogenesis. The Cell biology study combines topics in areas such as Chromatin and Axoneme.
His Male infertility research is classified as research in Infertility. His biological study spans a wide range of topics, including Phenotype, Intraflagellar transport, Asthenozoospermia, Gene mutation and Cilium. His study explores the link between Globozoospermia and topics such as Candidate gene that cross with problems in Acrosome.
The scientist’s investigation covers issues in Sperm, Male infertility, Sperm flagellum, Genetics and Cell biology. Christophe Arnoult regularly ties together related areas like Axoneme in his Sperm studies. His study focuses on the intersection of Male infertility and fields such as Allele with connections in the field of Sterility, Genetic heterogeneity, Andrology and Infertility.
His research investigates the connection between Sperm flagellum and topics such as Asthenozoospermia that intersect with problems in Flagellum and Phenotype. He works in the field of Genetics, focusing on Mutation in particular. His work deals with themes such as Chromatin, Regulation of gene expression and RNA-binding protein, which intersect with Cell biology.
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Activation of mouse sperm T-type Ca2+ channels by adhesion to the egg zona pellucida
Christophe Arnoult;Richard A. Cardullo;Jose R. Lemos;Harvey M. Florman.
Proceedings of the National Academy of Sciences of the United States of America (1996)
Ca2+ Entry through Store-operated Channels in Mouse Sperm Is Initiated by Egg ZP3 and Drives the Acrosome Reaction
Christine M.B. O'Toole;Christophe Arnoult;Alberto Darszon;Richard A. Steinhardt.
Molecular Biology of the Cell (2000)
Control of the low voltage-activated calcium channel of mouse sperm by egg ZP3 and by membrane hyperpolarization during capacitation
Christophe Arnoult;Imrana G. Kazam;Pablo E. Visconti;Gregory S. Kopf.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella.
Mariem Ben Khelifa;Mariem Ben Khelifa;Mariem Ben Khelifa;Charles Coutton;Charles Coutton;Raoudha Zouari;Thomas Karaouzène;Thomas Karaouzène.
American Journal of Human Genetics (2014)
A Perspective on the Control of Mammalian Fertilization by Egg-Activated Ion Channels in Sperm: A Tale of Two Channels
Harvey M. Florman;Christophe Arnoult;Imrana G. Kazam;Chongqing Li.
Biology of Reproduction (1998)
Role of TLR9 in Anti-Nucleosome and Anti-DNA Antibody Production in lpr Mutation-Induced Murine Lupus
Aurelia Lartigue;Philippe Courville;Isabelle Auquit;Arnaud François.
Journal of Immunology (2006)
The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation.
Alexa S. Green;Alexa S. Green;Nicolas Chapuis;Nicolas Chapuis;Thiago Trovati Maciel;Lise Willems;Lise Willems.
ZP3-dependent activation of sperm cation channels regulates acrosomal secretion during mammalian fertilization.
Christophe Arnoult;Yang Zeng;Harvey M. Florman.
Journal of Cell Biology (1996)
A Recurrent Deletion of DPY19L2 Causes Infertility in Man by Blocking Sperm Head Elongation and Acrosome Formation
Radu Harbuz;Radu Harbuz;Raoudha Zouari;Virginie Pierre;Virginie Pierre;Mariem Ben Khelifa;Mariem Ben Khelifa.
American Journal of Human Genetics (2011)
Teratozoospermia: spotlight on the main genetic actors in the human
Charles Coutton;Jessica Escoffier;Guillaume Martinez;Christophe Arnoult.
Human Reproduction Update (2015)
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