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Biology and Biochemistry

D-Index
64
Citations
13609
World Ranking
9745
National Ranking
4288

Overview

Robert L. Margolis is affiliated with the Sanford Burnham Prebys Medical Discovery Institute in the United States. Their research spans several interdisciplinary fields, including Agricultural and Biological Sciences, Biochemistry, Genetics and Molecular Biology, and Materials Science.

The scientist's work extends into multiple subfields of study, such as Plant Science, Molecular Biology, and Materials Chemistry. Their scholarly contributions address key topics in Chromosomal and Genetic Variations, Glycosylation and Glycoproteins Research, and Enzyme Structure and Function.

One of the documented publications authored by Robert L. Margolis is titled "Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant" published in 2020 within the UNC Libraries. This paper explores molecular biology aspects related to centromeric histone variants.

Collaborative research with frequent co-authors has been part of their scholarly activities. Notable co-authors include:

  • William C. Earnshaw
  • Robin C. Allshire
  • Ben E. Black
  • Kerry Bloom
  • B. R. Brinkley

The research outputs of Robert L. Margolis have been primarily published in venues such as UNC Libraries, which aligns with their focus on molecular biology and related biomedical topics.

Best Publications

  • Opposite end assembly and disassembly of microtubules at steady state in vitro

    Robert L. Margolis;Leslie Wilson

  • Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase.

    K Salim;M J Bottomley;E Querfurth;M J Zvelebil

  • Purification of the centromere-specific protein CENP-A and demonstration that it is a distinctive histone.

    Douglas K. Palmer;Kathleen O'Day;Hai Le Trong;Harry Charbonneau

  • A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles and with histones

    Douglas K. Palmer;Kathleen O'Day;Mark H. Wener;Brian S. Andrews

  • PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone

    Cristiana Mollinari;Jean-Philippe Kleman;Wei Jiang;Guy Schoehn

  • Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1.

    Paul R. Andreassen;Olivier D. Lohez;Françoise B. Lacroix;Robert L. Margolis

  • Microtubule treadmills--possible molecular machinery.

    Robert L. Margolis;Leslie Wilson

  • Addition of colchicine-tubulin complex to microtubule ends: The mechanism of substoichiometric colchicine poisoning

    Robert L. Margolis;Leslie Wilson

  • Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints.

    Dimitrios A. Skoufias;Paul R. Andreassen;Françoise B. Lacroix;Leslie Wilson

  • Crystal Structure of Human Survivin Reveals a Bow Tie–Shaped Dimer with Two Unusual α-Helical Extensions

    Laurent Chantalat;Dimitrios A. Skoufias;Jean Philippe Kleman;Barbara Jung

  • Human Survivin Is a Kinetochore-Associated Passenger Protein

    Dimitrios A. Skoufias;Cristiana Mollinari;Françoise B. Lacroix;Robert L. Margolis

  • G1 tetraploidy checkpoint and the suppression of tumorigenesis.

    Robert L. Margolis;Olivier D. Lohez;Paul R. Andreassen

  • Mitotic mechanism based on intrinsic microtubule behaviour

    Margolis Rl;Wilson L;Keifer Bi

  • In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities

    Salvatore DeBonis;Dimitrios A. Skoufias;Luc Lebeau;Roman Lopez

  • Differential Subcellular Localization of Protein Phosphatase-1 α, γ1, and δ Isoforms during Both Interphase and Mitosis in Mammalian Cells

    Paul R. Andreassen;Françoise B. Lacroix;Emma Villa-Moruzzi;Robert L. Margolis

  • Mitogen-activated protein kinase kinase activity is required for the G2/M transition of the cell cycle in mammalian fibroblasts

    Jocelyn H. Wright;Erlynda Munar;Damon R. Jameson;Paul R. Andreassen

  • Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells

    Franck Borel;Olivier D. Lohez;Françoise B. Lacroix;Robert L. Margolis

  • Microtubule treadmilling: what goes around comes around

    Robert L. Margolis;Leslie Wilson

  • Rapid disassembly of cold-stable microtubules by calmodulin.

    Didier Job;Edmond H. Fischer;Robert L. Margolis

  • The centromere specific histone CENP-A is selectively retained in discrete foci in mammalian sperm nuclei.

    Douglas K. Palmer;Kathleen O'Day;Robert L. Margolis

Frequent Co-Authors

Didier Job
Didier Job Grenoble Alpes University
Leslie Wilson
Leslie Wilson University of California, San Francisco
Paul R. Andreassen
Paul R. Andreassen Cincinnati Children's Hospital Medical Center
Edmond H. Fischer
Edmond H. Fischer University of Washington
Stefan Dimitrov
Stefan Dimitrov Grenoble Alpes University
Ivan Gout
Ivan Gout University College London
Mike Waterfield
Mike Waterfield Ludwig Cancer Research
Otto Dideberg
Otto Dideberg Centre national de la recherche scientifique, CNRS
Bruno Goud
Bruno Goud Institute Curie
Guy Schoehn
Guy Schoehn Grenoble Alpes University

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