World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
60
Citations
12268
World Ranking
9736
National Ranking
350

Biology and Biochemistry

D-Index
60
Citations
12203
World Ranking
12011
National Ranking
434

Overview

Otto Dideberg is affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their research primarily encompasses the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions also in Medicine.

The scientist's work focuses on several main topics, including:

  • Bacterial Genetics and Biotechnology
  • Antibiotic Resistance in Bacteria
  • Genomics and Phylogenetic Studies
  • Bacteriophages and microbial interactions
  • Microbial Natural Products and Biosynthesis
  • Streptococcal Infections and Treatments
  • Antibiotics Pharmacokinetics and Efficacy

Dideberg's subfields of study include Molecular Biology, Genetics, Molecular Medicine, Ecology, and Pharmacology. Their frequent publication venues reflect a diverse set of scientific journals and include:

  • Nature Communications
  • Structure
  • Experimental Biology and Medicine
  • Protein Science
  • Metabolites

Some of the recent papers authored or coauthored by Otto Dideberg are as follows:

  • "Bacterial secretins: Mechanisms of assembly and membrane targeting" (2020), published in Protein Science
  • "Penicillin-binding protein (PBP) inhibitor development: A 10-year chemical perspective" (2023), published in Experimental Biology and Medicine
  • "Chemical Elicitors Induce Rare Bioactive Secondary Metabolites in Deep-Sea Bacteria under Laboratory Conditions" (2021), published in Metabolites
  • "Self-association of MreC as a regulatory signal in bacterial cell wall elongation" (2021), published in Nature Communications
  • "Architecture and genomic arrangement of the MurE-MurF bacterial cell wall biosynthesis complex" (2023), published in Proceedings of the National Academy of Sciences

The scientist has collaborated frequently with other researchers, including:

  • Carlos Contreras-Martel
  • Daniel Maragno Trindade
  • Fernanda Rodrigues-Costa
  • Ina Attrée
  • Pauline Machebœuf

Best Publications

  • The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold.

    A. Carfi;S. Pares;E. Duée;Moreno Galleni

  • Penicillin Binding Proteins: key players in bacterial cell cycle and drug resistance processes

    Pauline Macheboeuf;Carlos Contreras-Martel;Viviana Job;Otto Dideberg

  • Standard Numbering Scheme for Class B β-Lactamases

    Moreno Galleni;Josette Lamotte-Brasseur;Gian Maria Rossolini;Jim Spencer

  • The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family.

    B Joris;J M Ghuysen;G Dive;A Renard

  • Update of the Standard Numbering Scheme for Class B β-Lactamases

    Gianpiero Garau;Isabel García-Sáez;Carine Bebrone;Christine Anne

  • Crystal Structure of Human Survivin Reveals a Bow Tie–Shaped Dimer with Two Unusual α-Helical Extensions

    Laurent Chantalat;Dimitrios A. Skoufias;Jean Philippe Kleman;Barbara Jung

  • The Crystal Structure of the Penicillin-Binding Protein 2x From Streptococcus Pneumoniae and Its Acyl-Enzyme Form: Implication in Drug Resistance

    E.J Gordon;N Mouz;E Duee;O. Dideberg

  • A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem.

    Gianpiero Garau;Carine Bebrone;Christine Anne;Moreno Galleni

  • On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target

    Judith A. Kelly;Otto Dideberg;Paulette Charlier;Jean-Pierre Wery

  • The kappa-carrageenase of P. carrageenovora features a tunnel-shaped active site: a novel insight in the evolution of Clan-B glycoside hydrolases.

    Gurvan Michel;Laurent Chantalat;Emile Duee;Tristan Barbeyron

  • X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme

    S. Pares;N. Mouz;Y. Pétillot;R. Hakenbeck

  • Mechanism of acyl transfer by the class A serine β-lactamase of Streptomyces albus G

    Josette Lamotte-Brasseur;Georges Dive;Otto Dideberg;Paulette Charlier

  • Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins.

    Bernard Joris;P. Ledent;O. Dideberg;E. Fonze

  • Beta-lactamase of Bacillus licheniformis 749/C at 2 A resolution.

    Paul C. Moews;James R. Knox;Otto Dideberg;Paulette Charlier

  • Crystal structure of the human protein kinase CK2 regulatory subunit reveals its zinc finger-mediated dimerization.

    Laurent Chantalat;Didier Leroy;Odile Filhol;Arsenio Nueda

  • Crystal Structure of UDP-N-acetylmuramoyl-l-alanyl-d-glutamate:meso-Diaminopimelate Ligase from Escherichia Coli

    Elspeth Gordon;Bernard Flouret;Laurent Chantalat;Jean van Heijenoort

  • The crystal structure of the β-lactamase of Streptomyces albus G at 0.3 nm resolution

    Otto Dideberg;Paulette Charlier;Jean-Paul Wery;Philippe Dehottay

  • 1.85 A resolution structure of the zinc (II) beta-lactamase from Bacillus cereus.

    Andrea Carfi;Emile Duée;Moreno Galleni;Jean-Marie Frère

  • The Three-Dimensional Structure of VIM-2, a Zn-β-Lactamase from Pseudomonas aeruginosa in Its Reduced and Oxidised Form

    I. Garcia-Saez;Jean-Denis Docquier;G. M. Rossolini;O. Dideberg

  • Determination of the MurD mechanism through crystallographic analysis of enzyme complexes.

    J.A Bertrand;G Auger;L Martin;E Fanchon

  • Crystal structure of Proteus mirabilis PR catalase with and without bound NADPH.

    Patrice Gouet;Hélène-Marie Jouve;Otto Dideberg

Frequent Co-Authors

Jean-Marie Frère
Jean-Marie Frère University of Liège
Jean-Marie Ghuysen
Jean-Marie Ghuysen University of Liège
Thierry Vernet
Thierry Vernet French Alternative Energies and Atomic Energy Commission (CEA)
Moreno Galleni
Moreno Galleni University of Liège
Bernard Joris
Bernard Joris University of Liège
Andréa Dessen
Andréa Dessen Brazilian Biosciences National Laboratory
Bernard Pirotte
Bernard Pirotte University of Liège
Andrea Carfi
Andrea Carfi Novartis (Switzerland)
Bernard Kloareg
Bernard Kloareg Centre national de la recherche scientifique, CNRS
Didier Blanot
Didier Blanot University of Paris-Saclay

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