World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
12981
World Ranking
13108
National Ranking
63

Overview

What is she best known for?

The fields of study she is best known for:

  • Enzyme
  • Gene
  • Amino acid

Her scientific interests lie mostly in Biochemistry, Protein structure, Cell biology, Periplasmic space and Secretion. In her works, Andréa Dessen undertakes multidisciplinary study on Biochemistry and NADH binding. Her research in Protein structure intersects with topics in Phospholipase A2, Biophysics, Protein folding, Molecular biology and Peptide sequence.

Within one scientific family, Andréa Dessen focuses on topics pertaining to Type three secretion system under Periplasmic space, and may sometimes address concerns connected to Macromolecule, Bacteria, Cytosol, Small molecule and Biogenesis. Her research on Secretion also deals with topics like

  • Translocon which is related to area like Pseudomonas, Host cell cytoplasm, Chaperone, Pseudomonas aeruginosa and Cytoplasm,
  • Membrane that connect with fields like Cell and Viral envelope. Andréa Dessen interconnects Cell division and Penicillin binding proteins in the investigation of issues within Peptidoglycan.

Her most cited work include:

  • Atomic structure of the ectodomain from HIV-1 gp41 (1476 citations)
  • Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis. (367 citations)
  • X-ray crystal structure of HLA-DR4 (DRA0101, DRB10401) complexed with a peptide from human collagen II. (336 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are Biochemistry, Microbiology, Cell biology, Peptidoglycan and Secretion. Her research related to Penicillin binding proteins, Periplasmic space, Enzyme, Protein structure and Bacterial outer membrane might be considered part of Biochemistry. The study incorporates disciplines such as Amino acid and Molecular biology in addition to Protein structure.

Her Cell biology research is multidisciplinary, incorporating perspectives in Operon, Peptide sequence, Type three secretion system and Bacteria. Her Peptidoglycan research incorporates elements of DNA ligase, Biosynthesis, Bacterial cell structure and Active site. In her study, Protein folding is strongly linked to Chaperone, which falls under the umbrella field of Secretion.

She most often published in these fields:

  • Biochemistry (48.72%)
  • Microbiology (27.56%)
  • Cell biology (23.72%)

What were the highlights of her more recent work (between 2014-2021)?

  • Cell biology (23.72%)
  • Microbiology (27.56%)
  • Peptidoglycan (20.51%)

In recent papers she was focusing on the following fields of study:

Andréa Dessen mainly investigates Cell biology, Microbiology, Peptidoglycan, Secretion and Virulence. Her studies in Cell biology integrate themes in fields like Prokaryotic cytoskeleton, Periplasmic space, Cell division and Cytoskeleton. Her Microbiology study incorporates themes from Helicobacter pylori and Pilus.

Biochemistry and Cell wall are all intrinsically tied to her study in Peptidoglycan. She undertakes interdisciplinary study in the fields of Biochemistry and Cheminformatics through her works. Andréa Dessen has researched Secretion in several fields, including Transport protein, Vibrio vulnificus and Effector.

Between 2014 and 2021, her most popular works were:

  • FtsZ filament capping by MciZ, a developmental regulator of bacterial division (42 citations)
  • New strategies for targeting and treatment of multi-drug resistant Staphylococcus aureus (36 citations)
  • Molecular architecture of the PBP2–MreC core bacterial cell wall synthesis complex (30 citations)

In her most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

Her main research concerns Cell biology, Virulence, Biochemistry, Extracellular and Effector. Her studies deal with areas such as Cell division, Prokaryotic cytoskeleton and Cytoskeleton as well as Cell biology. Her Virulence research incorporates themes from Antibiotics, Microbiology, Staphylococcus aureus, Efflux and RNA-binding protein.

Her Biochemistry study frequently links to related topics such as Bacterial cell structure. Her Extracellular study integrates concerns from other disciplines, such as RIG-I, Innate immune system, Pathogen, Extracellular RNA and Listeria monocytogenes. Her Effector study also includes

  • Pseudomonas aeruginosa and related In vitro, Biophysics, Mutagenesis and In vivo,
  • Secretion most often made with reference to Virulence factor.

Best Publications

  • Atomic structure of the ectodomain from HIV-1 gp41

    W. Weissenhorn;A. Dessen;S. C. Harrison;S. C. Harrison;J. J. Skehel

  • Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis.

    Andrea Dessen;Annaik Quemard;John S. Blanchard;William R. Jacobs

  • Penicillin Binding Proteins: key players in bacterial cell cycle and drug resistance processes

    Pauline Macheboeuf;Carlos Contreras-Martel;Viviana Job;Otto Dideberg

  • Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis.

    Annaiek Quemard;James C. Sacchettini;Andrea Dessen;Catherine Vilcheze

  • Crystal structure of human cytosolic phospholipase A2 reveals a novel topology and catalytic mechanism.

    Andréa Dessen;Jin Tang;Holly Schmidt;Mark Stahl

  • Structural basis for membrane fusion by enveloped viruses

    W Weissenhorn;A Dessen;L J Calder;S C Harrison

  • X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II.

    Andréa Dessen;C.Martin Lawrence;Susan Cupo;Dennis M. Zaller

  • The V Antigen of Pseudomonas aeruginosa Is Required for Assembly of the Functional PopB/PopD Translocation Pore in Host Cell Membranes

    Julien Goure;Alexandrine Pastor;Eric Faudry;Jacqueline Chabert

  • Crystal structure of the matrix protein VP40 from Ebola virus

    Andréa Dessen;Viktor Volchkov;Olga Dolnik;Hans‐Dieter Klenk

  • Structural characterization and membrane binding properties of the matrix protein VP40 of Ebola virus.

    Rob W.H Ruigrok;Guy Schoehn;Andréa Dessen;Eric Forest

  • A Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response

    Alice Lebreton;Alice Lebreton;Alice Lebreton;Goran Lakisic;Viviana Job;Lauriane Fritsch

  • X-ray crystal structure of the soybean agglutinin cross-linked with a biantennary analog of the blood group I carbohydrate antigen

    A Dessen;D Gupta;S Sabesan;C F Brewer

  • Oligomerization of type III secretion proteins PopB and PopD precedes pore formation in Pseudomonas.

    Guy Schoehn;Anne Marie Di Guilmi;David Lemaire;Ina Attree

  • The Matrix Protein Vp40 from Ebola Virus Octamerizes Into Pore-Like Structures with Specific RNA Binding Properties

    F Xavier Gomis-Rüth;Andréa Dessen;Joanna Timmins;Andreas Bracher

  • Resistance to antibiotics targeted to the bacterial cell wall.

    I Nikolaidis;S Favini-Stabile;A Dessen

  • The SciZ protein anchors the enteroaggregative Escherichia coli Type VI secretion system to the cell wall.

    Marie-Stéphanie Aschtgen;Marthe Gavioli;Andrea Dessen;Roland Lloubès

  • Structural Basis of Host Cell Recognition by the Pilus Adhesin from Streptococcus pneumoniae

    Thierry Izoré;Carlos Contreras-Martel;Lamya El Mortaji;Clothilde Manzano

  • Membrane targeting and pore formation by the type III secretion system translocon.

    Pierre-Jean Matteï;Eric Faudry;Viviana Job;Thierry Izoré

  • Biogenesis, Regulation, and Targeting of the Type III Secretion System

    Thierry Izoré;Thierry Izoré;Viviana Job;Viviana Job;Andréa Dessen;Andréa Dessen

  • Crystal Structure of PBP2x from a Highly Penicillin-resistant Streptococcus pneumoniae Clinical Isolate A MOSAIC FRAMEWORK CONTAINING 83 MUTATIONS

    Andréa Dessen;Nicolas Mouz;Elspeth Gordon;Julie Hopkins

Frequent Co-Authors

Thierry Vernet
Thierry Vernet French Alternative Energies and Atomic Energy Commission (CEA)
Pascale Cossart
Pascale Cossart Institut Pasteur
Stanislav Gobec
Stanislav Gobec University of Ljubljana
Guy Schoehn
Guy Schoehn Grenoble Alpes University
Didier Blanot
Didier Blanot University of Paris-Saclay
Otto Dideberg
Otto Dideberg Centre national de la recherche scientifique, CNRS
Marie-Anne Nahori
Marie-Anne Nahori Institut Pasteur
Winfried Weissenhorn
Winfried Weissenhorn Grenoble Alpes University
Patrick England
Patrick England Institut Pasteur
Anthony P. Pugsley
Anthony P. Pugsley Institut Pasteur

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