World's Best Scientists 2026 revealed!
James C. Sacchettini

James C. Sacchettini

D-Index & Metrics

Biology and Biochemistry

D-Index
120
Citations
48646
World Ranking
648
National Ranking
413

James C. Sacchettini publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where James C. Sacchettini sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 624 publications — 97th percentile

97% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

James C. Sacchettini D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where James C. Sacchettini sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 120 D-Index — 97th percentile

97% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

James C. Sacchettini is affiliated with Texas A&M University in the United States. Their research contributions focus primarily on the fields of medicine and biochemistry, genetics, and molecular biology.

The core subfields of their work include infectious diseases, molecular biology, and epidemiology. These areas reflect an emphasis on understanding disease mechanisms and biological processes at the molecular level.

James C. Sacchettini's main research topics cover tuberculosis research and epidemiology, RNA and protein synthesis mechanisms, and Pneumocystis jirovecii pneumonia detection and treatment. These topics indicate a concentration on infectious disease pathogenesis and therapeutic strategies.

The scientist has published in the following venues:

  • Cell

Their recent publication is titled "Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents", published in 2023 in the journal Cell. This work has been cited in the academic literature 21 times.

Frequent co-authors collaborating with James C. Sacchettini include:

  • Jidong Zhang
  • Christine Lair
  • Christine Roubert
  • Kwame Amaning
  • María Belén Pascual Barrio

Best Publications

  • PHENIX: building new software for automated crystallographic structure determination

    Paul D Adams;Ralf W Grosse-Kunstleve;Li Wei Hung;Thomas R Ioerger

  • Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase

    John D. McKinney;John D. McKinney;John D. McKinney;Kerstin Höner Zu Bentrup;Kerstin Höner Zu Bentrup;Kerstin Höner Zu Bentrup;Ernesto J. Muñoz-Elias;Andras Miczak;Andras Miczak

  • Crystal structure of a plant catechol oxidase containing a dicopper center.

    Thomas Klabunde;Christoph Eicken;James C. Sacchettini;Bernt Krebs

  • Modification of the NADH of the Isoniazid Target (InhA) from Mycobacterium tuberculosis

    Denise A. Rozwarski;Gregory A. Grant;Derek H. R. Barton;William R. Jacobs

  • Creating Isoprenoid Diversity

    James C. Sacchettini;C. Dale Poulter

  • Automated Structure Solution with the PHENIX Suite

    Peter H. Zwart;Pavel V. Afonine;Ralf W. Grosse-Kunstleve;Li-Wei Hung

  • Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

    Philana Ling Lin;Christopher B Ford;Christopher B Ford;M Teresa Coleman;Amy J Myers

  • Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis.

    Andrea Dessen;Annaik Quemard;John S. Blanchard;William R. Jacobs

  • Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-A resolution.

    L.C Tarshis;M Yan;C.D Poulter;J.C. Sacchettini

  • Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

    Christopher B Ford;Philana Ling Lin;Michael R Chase;Rupal R Shah

  • Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis.

    Annaiek Quemard;James C. Sacchettini;Andrea Dessen;Catherine Vilcheze

  • Crystal structure of rat intestinal fatty-acid-binding protein. Refinement and analysis of the Escherichia coli-derived protein with bound palmitate.

    James C. Sacchettini;Jeffrey I. Gordon;Leonard J. Banaszak

  • An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance.

    L J Baier;J C Sacchettini;W C Knowler;J Eads

  • Rational design of potent human transthyretin amyloid disease inhibitors.

    T. Klabunde;H.M. Petrassi;V.B. Oza;P. Raman

  • Regulation of product chain length by isoprenyl diphosphate synthases.

    L.C Tarshis;P.J Proteau;B.A Kellogg;J.C Sacchettini

  • Recent developments in the PHENIX software for automated crystallographic structure determination

    Paul D. Adams;Kreshna Gopal;Ralf W. Grosse-Kunstleve;Li-Wei Hung

  • Multivalent protein-carbohydrate interactions. A new paradigm for supermolecular assembly and signal transduction.

    J C Sacchettini;L G Baum;C F Brewer

  • Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition.

    Weiguo Zhang;Aideen C. M. Young;Monica Imarai;Stanley G. Nathenson

  • Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid.

    Catherine Vilchèze;Feng Wang;Masayoshi Arai;Manzour Hernando Hazbón

  • Therapeutic strategies for human amyloid diseases

    James C. Sacchettini;Jeffery W. Kelly

Frequent Co-Authors

Thomas R. Ioerger
Thomas R. Ioerger Texas A&M University
William R. Jacobs
William R. Jacobs Albert Einstein College of Medicine
Eric J. Rubin
Eric J. Rubin Harvard University
Tanya Parish
Tanya Parish Seattle Children's Hospital
Jeffrey I. Gordon
Jeffrey I. Gordon Washington University in St. Louis
Catherine Vilchèze
Catherine Vilchèze Albert Einstein College of Medicine
Laurent Kremer
Laurent Kremer Institut de Recherche en Infectiologie de Montpellier
Giovanna Scapin
Giovanna Scapin MSD (United States)
Kyu Y. Rhee
Kyu Y. Rhee Cornell University
Gurdyal S. Besra
Gurdyal S. Besra University of Birmingham

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