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Microbiology

D-Index
53
Citations
10252
World Ranking
4090
National Ranking
1584

Overview

Catherine Vilchèze is affiliated with the Albert Einstein College of Medicine in the United States. Their research primarily focuses on infectious diseases, with an emphasis on tuberculosis and mycobacterial studies. Their expertise encompasses molecular biology, epidemiology, and the diagnosis and treatment of tuberculosis, integrating biochemical and molecular research approaches.

The scientist's main fields of study include:

  • Medicine

Within this, their subfields of study are:

  • Infectious Diseases
  • Epidemiology
  • Molecular Biology
  • Surgery
  • Ecology

Vilchèze's research topics also cover:

  • Tuberculosis Research and Epidemiology
  • Mycobacterium research and diagnosis
  • Biochemical and Molecular Research
  • Diagnosis and treatment of tuberculosis
  • Cancer therapeutics and mechanisms
  • Bacteriophages and microbial interactions
  • Pneumocystis jirovecii pneumonia detection and treatment

Their scholarly output includes publications in notable venues such as:

  • Antimicrobial Agents and Chemotherapy
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • mBio
  • Applied Sciences

Recent papers by Vilchèze include:

  • "Mycobacterial Cell Wall: A Source of Successful Targets for Old and New Drugs," 2020, Applied Sciences
  • "The Promises and Limitations of N-Acetylcysteine as a Potentiator of First-Line and Second-Line Tuberculosis Drugs," 2021, Antimicrobial Agents and Chemotherapy
  • "Commonalities of Mycobacterium tuberculosis Transcriptomes in Response to Defined Persisting Macrophage Stresses," 2022, Frontiers in Immunology

Among frequent coauthors are:

  • William R. Jacobs
  • Rajagopalan Saranathan
  • Michael Berney
  • Lahari Das
  • Claire V. Mulholland

Best Publications

  • Effect of the Structure of Natural Sterols and Sphingolipids on the Formation of Ordered Sphingolipid/Sterol Domains (Rafts) COMPARISON OF CHOLESTEROL TO PLANT, FUNGAL, AND DISEASE-ASSOCIATED STEROLS AND COMPARISON OF SPHINGOMYELIN, CEREBROSIDES, AND CERAMIDE

    Xiaolian Xu;Robert Bittman;Guy Duportail;Denis Heissler

  • Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis.

    Annaiek Quemard;James C. Sacchettini;Andrea Dessen;Catherine Vilcheze

  • The Mechanism of Isoniazid Killing: Clarity Through the Scope of Genetics

    Catherine Vilchèze;William R. Jacobs

  • Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid.

    Catherine Vilchèze;Feng Wang;Masayoshi Arai;Manzour Hernando Hazbón

  • Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction

    Catherine Vilchèze;Travis Hartman;Brian Weinrick;William R. Jacobs

  • Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis.

    Catherine Vilchèze;Hector R. Morbidoni;Torin R. Weisbrod;Hiroyuki Iwamoto

  • Pyrazinamide inhibits the eukaryotic-like fatty acid synthetase I (FASI) of Mycobacterium tuberculosis

    Oren Zimhony;Jeffery S. Cox;John T. Welch;Catherine Vilchèze

  • Crystal Structure of the Mycobacterium tuberculosis Enoyl-ACP Reductase, InhA, in Complex with NAD+ and a C16 Fatty Acyl Substrate

    Denise A. Rozwarski;Catherine Vilchèze;Michele Sugantino;Robert Bittman

  • The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.

    Min Yu;T. R.Santha Kumar;T. R.Santha Kumar;Louis J. Nkrumah;Alida Coppi

  • Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis

    Michael B. Harbut;Catherine Vilchèze;Xiaozhou Luo;Mary E. Hensler

  • Altered NADH/NAD+ Ratio Mediates Coresistance to Isoniazid and Ethionamide in Mycobacteria

    Catherine Vilchèze;Torin R. Weisbrod;Bing Chen;Laurent Kremer

  • Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities

    Catherine Vilchèze;William R. Jacobs

  • Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis

    Michelle H. Larsen;Catherine Vilchèze;Laurent Kremer;Gurdyal S. Besra

  • Energetics of Respiration and Oxidative Phosphorylation in Mycobacteria

    Gregory M. Cook;Kiel Hards;Catherine Vilchèze;Travis Hartman

  • Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence

    Jo Ann M. Tufariello;Jessica R. Chapman;Christopher A. Kerantzas;Ka Wing Wong

  • Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis

    Catherine Vilchèze;Travis Hartman;Brian Weinrick;Brian Weinrick;Paras Jain

  • Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis

    Catherine Vilchèze;Yossef Av-Gay;Rodgoun Attarian;Zhen Liu

  • Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis.

    Joel S. Freundlich;Joel S. Freundlich;Feng Wang;Feng Wang;Catherine Vilchèze;Gulcin Gulten

  • Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteria.

    Patamaporn Pruksakorn;Masayoshi Arai;Naoyuki Kotoku;Catherine Vilchèze

  • Transcriptional Regulation of Multi-Drug Tolerance and Antibiotic-Induced Responses by the Histone-Like Protein Lsr2 in M. tuberculosis

    Roberto Colangeli;Danica Helb;Catherine Vilchèze;Manzour Hernando Hazbón

Frequent Co-Authors

William R. Jacobs
William R. Jacobs Albert Einstein College of Medicine
Laurent Kremer
Laurent Kremer Institut de Recherche en Infectiologie de Montpellier
Robert Bittman
Robert Bittman City University of New York
James C. Sacchettini
James C. Sacchettini Texas A&M University
David Alland
David Alland Rutgers, The State University of New Jersey
Gurdyal S. Besra
Gurdyal S. Besra University of Birmingham
Graham F. Hatfull
Graham F. Hatfull University of Pittsburgh
Yossef Av-Gay
Yossef Av-Gay University of British Columbia
Charles J. Thompson
Charles J. Thompson University of British Columbia
Steven A. Porcelli
Steven A. Porcelli Albert Einstein College of Medicine

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