D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 58 Citations 11,200 227 World Ranking 8901 National Ranking 4000

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • DNA

His main research concerns Microbiology, Mycobacterium tuberculosis, Biochemistry, Dormancy and Mycobacterium bovis. His work deals with themes such as Bacilli, Bacteria, In vitro and Intracellular, which intersect with Microbiology. The concepts of his Mycobacterium tuberculosis study are interwoven with issues in Multiple drug resistance, Drug resistance, Virology, Immunology and Adenosine triphosphate.

His Immunology study incorporates themes from Clinical disease and Latent tuberculosis. His Biochemistry research includes elements of Nitric oxide and Respiration. His Mycobacterium bovis research is multidisciplinary, relying on both Response regulator, Downregulation and upregulation and Metronidazole.

His most cited work include:

  • The spectrum of latent tuberculosis: rethinking the biology and intervention strategies (945 citations)
  • The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis (353 citations)
  • Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis (259 citations)

What are the main themes of his work throughout his whole career to date?

Thomas Dick focuses on Mycobacterium tuberculosis, Biochemistry, Microbiology, Mutant and Enzyme. His Mycobacterium tuberculosis research incorporates elements of Drug resistance, Pharmacology, Drug discovery and Virology. His Pharmacology study integrates concerns from other disciplines, such as Potency and In vivo.

His Biochemistry study typically links adjacent topics like Mycobacterium. His research in Microbiology intersects with topics in Bacilli, Bacteria, Mycobacterium bovis and Mycobacterium abscessus. ATP synthase is the focus of his Enzyme research.

He most often published in these fields:

  • Mycobacterium tuberculosis (40.10%)
  • Biochemistry (40.62%)
  • Microbiology (30.73%)

What were the highlights of his more recent work (between 2017-2021)?

  • Biochemistry (40.62%)
  • Mycobacterium tuberculosis (40.10%)
  • Mutant (19.79%)

In recent papers he was focusing on the following fields of study:

Thomas Dick mostly deals with Biochemistry, Mycobacterium tuberculosis, Mutant, ATP synthase and Mycobacterium abscessus. The study incorporates disciplines such as In vitro, Mechanism of action and Drug tolerance in addition to Mycobacterium tuberculosis. His Mutant study combines topics in areas such as Moiety, Docking, Recombinant DNA and Drug discovery.

He has researched ATP synthase in several fields, including ATP hydrolysis, Oxidative phosphorylation, Protein subunit, Cell biology and Bedaquiline. The various areas that he examines in his Mycobacterium abscessus study include Clarithromycin, Antibiotics, Rifabutin and Microbiology. When carried out as part of a general Microbiology research project, his work on Drug resistance and Multiple drug resistance is frequently linked to work in Genetic association, therefore connecting diverse disciplines of study.

Between 2017 and 2021, his most popular works were:

  • NTM drug discovery: status, gaps and the way forward (63 citations)
  • Verapamil Targets Membrane Energetics in Mycobacterium tuberculosis. (38 citations)
  • The NMR solution structure of Mycobacterium tuberculosis F‐ATP synthase subunit ε provides new insight into energy coupling inside the rotary engine (25 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

Thomas Dick spends much of his time researching Mycobacterium tuberculosis, Biochemistry, ATP synthase, Binding site and Drug resistance. His Mycobacterium tuberculosis study combines topics from a wide range of disciplines, such as Mechanism of action, In vitro, Cytotoxicity, Drug tolerance and Coenzyme A. His research on In vitro often connects related topics like Microbiology.

His research in ATP synthase focuses on subjects like Protein subunit, which are connected to ATP hydrolysis, Mutagenesis, Amino acid, Protein Data Bank and Stereochemistry. His biological study spans a wide range of topics, including Allosteric regulation and Enzyme. His Drug resistance research also works with subjects such as

  • Intensive care medicine which is related to area like MEDLINE and Drug development,
  • Mycobacterium Infections which is related to area like Drug discovery, Drug and Drug pipeline.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

Clifton E. Barry;Helena I. Boshoff;Véronique Dartois;Thomas Dick.
Nature Reviews Microbiology (2009)

1454 Citations

The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

Srinivasa P. S. Rao;Sylvie Alonso;Lucinda Rand;Lucinda Rand;Thomas Dick.
Proceedings of the National Academy of Sciences of the United States of America (2008)

473 Citations

Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis

Ujjini H. Manjunatha;Helena Boshoff;Cynthia S. Dowd;Liang Zhang.
Proceedings of the National Academy of Sciences of the United States of America (2006)

407 Citations

Mycobacterium bovis BCG Response Regulator Essential for Hypoxic Dormancy

Calvin Boon;Thomas Dick.
Journal of Bacteriology (2002)

330 Citations

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

Kevin Pethe;Patricia C. Sequeira;Sanjay Agarwalla;Kyu Rhee.
Nature Communications (2010)

273 Citations

Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability.

Martin Gengenbacher;Srinivasa P. S. Rao;Kevin Pethe;Thomas Dick.
Microbiology (2010)

230 Citations

Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster.

Thomas Dick;Krishanu Ray;Helen K. Salz;William Chia.
Molecular and Cellular Biology (1996)

203 Citations

Oxygen depletion induced dormancy in Mycobacterium smegmatis

Thomas Dick;Boon Heng Lee;Bernadette Murugasu-Oei.
Fems Microbiology Letters (1998)

198 Citations

Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis

Scott G. Franzblau;Mary Ann DeGroote;Sang Hyun Cho;Koen Andries.
Tuberculosis (2012)

184 Citations

Para-aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis

Jun Zheng;Eric J. Rubin;Pablo Bifani;Vanessa Mathys.
Journal of Biological Chemistry (2013)

173 Citations

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