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D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
13873
World Ranking
9726
National Ranking
4283

Overview

Thomas Dick is affiliated with Georgetown University in the United States and has contributed extensively to the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their research spans several subfields, including Epidemiology, Infectious Diseases, Molecular Biology, Organic Chemistry, and Small Animals.

Their work focuses predominantly on topics related to Mycobacterium research and diagnosis, Tuberculosis research and epidemiology, Infectious diseases and mycology, Quinazolinone synthesis and applications, Antibiotic resistance in bacteria, Biochemical and molecular research, and ATP synthase and ATPases research.

Thomas Dick has published numerous papers in respected scientific journals, with recent notable papers including:

  • Pyrazinamide triggers degradation of its target aspartate decarboxylase (2020, Nature Communications)
  • Indole Propionic Acid, an Unusual Antibiotic Produced by the Gut Microbiota, With Anti-inflammatory and Antioxidant Properties (2020, Frontiers in Microbiology)
  • Therapeutic developments for tuberculosis and nontuberculous mycobacterial lung disease (2024, Nature Reviews Drug Discovery)
  • Extreme Drug Tolerance of Mycobacterium abscessus "Persisters" (2020, Frontiers in Microbiology)
  • Critical discussion on drug efflux in Mycobacterium tuberculosis (2021, FEMS Microbiology Reviews)

They have collaborated frequently with several coauthors, including Véronique Dartois, Uday S. Ganapathy, Wassihun Wedajo Aragaw, Gerhard Grüber, and Jickky Palmae Sarathy.

Their research has been published in leading venues, with the highest number of publications appearing in:

  • Antimicrobial Agents and Chemotherapy (19 publications)
  • Microbiology Spectrum (6 publications)
  • The Cambridge Structural Database (6 publications)
  • ACS Infectious Diseases (5 publications)
  • Frontiers in Microbiology (3 publications)

Best Publications

  • The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

    Clifton E. Barry;Helena I. Boshoff;Véronique Dartois;Thomas Dick

  • The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

    Srinivasa P. S. Rao;Sylvie Alonso;Lucinda Rand;Lucinda Rand;Thomas Dick

  • Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis

    Ujjini H. Manjunatha;Helena Boshoff;Cynthia S. Dowd;Liang Zhang

  • Mycobacterium bovis BCG Response Regulator Essential for Hypoxic Dormancy

    Calvin Boon;Thomas Dick

  • A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

    Kevin Pethe;Patricia C. Sequeira;Sanjay Agarwalla;Kyu Rhee

  • Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability.

    Martin Gengenbacher;Srinivasa P. S. Rao;Kevin Pethe;Thomas Dick

  • Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis

    Scott G. Franzblau;Mary Ann DeGroote;Sang Hyun Cho;Koen Andries

  • Para-aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis

    Jun Zheng;Eric J. Rubin;Pablo Bifani;Vanessa Mathys

  • NTM drug discovery: status, gaps and the way forward

    Mu-Lu Wu;Dinah B. Aziz;Véronique Dartois;Thomas Dick

  • Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster.

    Thomas Dick;Krishanu Ray;Helen K. Salz;William Chia

  • Light-induced rescue of breathing after spinal cord injury.

    Warren J. Alilain;Xiang Li;Kevin P. Horn;Rishi Dhingra

  • Oxygen depletion induced dormancy in Mycobacterium smegmatis

    Thomas Dick;Boon Heng Lee;Bernadette Murugasu-Oei

  • Involvement of serotonin in the excitation of phrenic motoneurons evoked by stimulation of the raphe obscurus

    J. R. Holtman;Thomas E Dick;A. J. Berger

  • Proteins of Mycobacterium bovis BCG induced in the Wayne dormancy model.

    Calvin Boon;Rong Li;Robert Qi;Thomas Dick

  • Oxygen depletion-induced dormancy in Mycobacterium bovis BCG.

    Amanda Lim;Marianne Eleuterio;Bernd Hutter;Bernadette Murugasu-Oei

  • Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents

    Suresh B. Lakshminarayana;Tan Bee Huat;Paul C. Ho;Ujjini H. Manjunatha

  • Indolcarboxamide Is a Preclinical Candidate for Treating Multidrug-Resistant Tuberculosis

    Srinivasa P. S. Rao;Suresh B. Lakshminarayana;Ravinder R. Kondreddi;Maxime Herve

  • Reduced drug uptake in phenotypically resistant nutrient-starved nonreplicating Mycobacterium tuberculosis

    Jansy Sarathy;Véronique Dartois;Thomas Dick;Martin Gengenbacher

  • Triacylglycerol Utilization Is Required for Regrowth of In Vitro Hypoxic Nonreplicating Mycobacterium bovis Bacillus Calmette-Guerin

    Kai Leng Low;P. S. Srinivasa Rao;Guanghou Shui;Anne K. Bendt

  • Persistence of the biphasic ventilatory response to hypoxia in preterm infants

    Richard J. Martin;Juliann M. DiFiore;Laura Jana;Rebecca L. Davis

Frequent Co-Authors

Véronique Dartois
Véronique Dartois Rutgers, The State University of New Jersey
Helena I. Boshoff
Helena I. Boshoff National Institutes of Health
Clifton E. Barry
Clifton E. Barry National Institute of Allergy and Infectious Diseases
Eric J. Rubin
Eric J. Rubin Harvard University
Thomas H. Keller
Thomas H. Keller Novartis (Switzerland)
William Chia
William Chia National University of Singapore
Douglas B. Young
Douglas B. Young Imperial College London
Robert J. Wilkinson
Robert J. Wilkinson The Francis Crick Institute
Sabine Ehrt
Sabine Ehrt Cornell University
Dirk Schnappinger
Dirk Schnappinger Cornell University

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