World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
86
Citations
23549
World Ranking
2584
National Ranking
901

Biology and Biochemistry

D-Index
89
Citations
26551
World Ranking
2583
National Ranking
1352

Overview

Scott G. Franzblau is affiliated with the University of Illinois at Chicago in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology, with significant work in the subfields of molecular biology, organic chemistry, infectious diseases, pharmacology, and epidemiology.

Their scholarly contributions span a range of topics including tuberculosis research and epidemiology, cancer therapeutics and mechanisms, microbial natural products and biosynthesis, synthesis and biological evaluation, biochemical and molecular research, synthesis and biological activity, and research on leishmaniasis studies.

Key recent publications by Scott G. Franzblau include:

  • New tuberculosis drug targets, their inhibitors, and potential therapeutic impact, 2020, Translational Research
  • Antimycobacterial Rufomycin Analogues from Streptomyces atratus Strain MJM3502, 2020, Journal of Natural Products
  • Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors, 2020, European Journal of Medicinal Chemistry
  • Discovery and preclinical profile of sudapyridine (WX-081), a novel anti-tuberculosis agent, 2022, Bioorganic & Medicinal Chemistry Letters
  • Design, synthesis and biological evaluation of novel 1,2,3-triazole analogues of Imidazo-[1,2-a]-pyridine-3-carboxamide against Mycobacterium tuberculosis, 2021, Toxicology in Vitro

Frequent coauthors collaborating with Scott G. Franzblau include:

  • Gauri Shetye
  • Sang-Hyun Cho
  • Baojie Wan
  • Rui Ma
  • Mallique Qader

The scientist has published multiple works in journals such as:

  • European Journal of Medicinal Chemistry
  • Journal of Natural Products
  • The Cambridge Structural Database
  • ACS Infectious Diseases
  • Bioorganic & Medicinal Chemistry Letters

The body of work produced by Scott G. Franzblau consists of 61 publications in medicine and 56 in biochemistry, genetics, and molecular biology. Significant subfields include 48 publications in molecular biology and 30 in organic chemistry. Their research topics heavily center around tuberculosis, with 50 publications related to tuberculosis research and epidemiology, alongside key contributions to cancer therapeutics, microbial natural products, and biochemical research.

Best Publications

  • Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium.

    L A Collins;S G Franzblau

  • Rapid, Low-Technology MIC Determination with Clinical Mycobacterium tuberculosis Isolates by Using the Microplate Alamar Blue Assay

    Scott G. Franzblau;Richard S. Witzig;James C. McLaughlin;Patricia Torres

  • Thiosemicarbazones, semicarbazones, dithiocarbazates and hydrazide/ hydrazones: Anti - Mycobacterium tuberculosis activity and cytotoxicity

    Fernando Rogério Pavan;Pedro I. da S. Maia;Sergio R. A. Leite;Victor M. Deflon

  • Low-Oxygen-Recovery Assay for High-Throughput Screening of Compounds against Nonreplicating Mycobacterium tuberculosis

    Sang Hyun Cho;Saradee Warit;Baojie Wan;Chang Hwa Hwang

  • Antimycobacterial plant terpenoids.

    Charles L. Cantrell;Scott G. Franzblau;Nikolaus H. Fischer

  • Structure-activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating Mycobacterium tuberculosis.

    Annamaria Lilienkampf;Jialin Mao;Baojie Wan;Yuehong Wang

  • Improved Green Fluorescent Protein Reporter Gene-Based Microplate Screening for Antituberculosis Compounds by Utilizing an Acetamidase Promoter

    Chartchai Changsen;Scott G. Franzblau;Prasit Palittapongarnpim

  • Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis

    Scott G. Franzblau;Mary Ann DeGroote;Sang Hyun Cho;Koen Andries

  • In Vitro and In Vivo Activities of Macrolide Derivatives against Mycobacterium tuberculosis

    Kanakeshwari Falzari;Zhaohai Zhu;Dahua Pan;Huiwen Liu

  • Identification of a small molecule with activity against drug-resistant and persistent tuberculosis

    Feng Wang;Dhinakaran Sambandan;Rajkumar Halder;Jianing Wang

  • Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae).

    Jonel P. Saludes;Mary J. Garson;Scott G. Franzblau;Alicia M. Aguinaldo

  • L-arginine-dependent macrophage effector functions inhibit metabolic activity of Mycobacterium leprae.

    L B Adams;S G Franzblau;Z Vavrin;J B Hibbs

  • Novel Insights into the Mechanism of Inhibition of MmpL3, a Target of Multiple Pharmacophores in Mycobacterium tuberculosis

    Wei Li;Ashutosh Upadhyay;Fabio L. Fontes;E. Jeffrey North

  • Synthesis, antimalarial and antitubercular activity of acetylenic chalcones

    Renate H. Hans;Eric M. Guantai;Carmen Lategan;Peter J. Smith

  • Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents

    Bo Zhou;Yantao He;Xian Zhang;Xian Zhang;Jie Xu

  • New perspectives on natural products in TB drug research

    Guido F. Pauli;Ryan J. Case;Taichi Inui;Yuehong Wang

  • Drug Targeting Mycobacterium tuberculosis Cell Wall Synthesis: Genetics of dTDP-Rhamnose Synthetic Enzymes and Development of a Microtiter Plate-Based Screen for Inhibitors of Conversion of dTDP-Glucose to dTDP-Rhamnose

    Yufang Ma;Richard J. Stern;Michael S. Scherman;Varalakshmi D. Vissa

  • The Cyclic Peptide Ecumicin Targeting ClpC1 Is Active against Mycobacterium tuberculosis In Vivo

    Wei Gao;Jin Yong Kim;Jeffrey R. Anderson;Tatos Akopian

  • Advent of imidazo[1,2-a]pyridine-3-carboxamides with potent multi- and extended drug resistant antituberculosis activity

    Garrett C. Moraski;Lowell D. Markley;Philip A. Hipskind;Helena Boshoff

  • Antimycobacterial Activity of (E)-Phytol and Derivatives: A Preliminary Structure-Activity Study

    Mohamed S. Rajab;Charles L. Cantrell;Scott G. Franzblau;Nikolaus H. Fischer

Frequent Co-Authors

Guido F. Pauli
Guido F. Pauli University of Illinois at Chicago
William A. Denny
William A. Denny University of Auckland
Marvin J. Miller
Marvin J. Miller University of Notre Dame
Barbara N. Timmermann
Barbara N. Timmermann University of Kansas
James B. McAlpine
James B. McAlpine University of Illinois at Chicago
Brian D. Palmer
Brian D. Palmer University of Auckland
Charles L. Cantrell
Charles L. Cantrell United States Department of Agriculture
Louis Maes
Louis Maes University of Antwerp
Karine G. Le Roch
Karine G. Le Roch University of California, Riverside
Harry H. S. Fong
Harry H. S. Fong University of Illinois at Chicago

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