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Aleixo M. Muise

Aleixo M. Muise

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
11442
World Ranking
12071
National Ranking
416

Overview

Aleixo M. Muise is affiliated with the University of Toronto in Canada and has contributed extensively to the fields of Medicine, Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology. Their research is prominently focused on areas including Inflammatory Bowel Disease, Immunodeficiency and Autoimmune Disorders, and Microscopic Colitis, among others.

The scientist's body of work includes publications across a broad range of subfields such as Immunology, Genetics, Surgery, Molecular Biology, and Epidemiology. Notably, they have explored topics related to IL-33, ST2, and ILC Pathways, Digestive system and related health issues, Celiac Disease Research and Management, and Helicobacter pylori-related gastroenterology studies.

Some of the recent papers authored or co-authored by Aleixo M. Muise include:

  • Mucus sialylation determines intestinal host-commensal homeostasis (2022, Cell)
  • Clinical Genomics for the Diagnosis of Monogenic Forms of Inflammatory Bowel Disease (2020, Journal of Pediatric Gastroenterology and Nutrition)
  • A Systematic Review of Monogenic Inflammatory Bowel Disease (2021, Clinical Gastroenterology and Hepatology)
  • Prevalence and Clinical Features of Inflammatory Bowel Diseases Associated With Monogenic Variants, Identified by Whole-Exome Sequencing in 1000 Children at a Single Center (2020, Gastroenterology)
  • Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice (2021, Nature Genetics)

The frequent publication venues for Aleixo M. Muise's research include:

  • Gastroenterology
  • Journal of Crohn's and Colitis
  • Inflammatory Bowel Diseases
  • Journal of Pediatric Gastroenterology and Nutrition
  • Scientific Reports

Aleixo M. Muise has collaborated regularly with several co-authors in the field. Frequent co-authors include:

  • Scott B. Snapper
  • Neil Warner
  • Christoph Klein
  • Daniel Kotlarz
  • Anne M. Griffiths

Best Publications

  • The diagnostic approach to monogenic very early onset inflammatory bowel disease.

    Holm H. Uhlig;Tobias Schwerd;Sibylle Koletzko;Neil Shah;Neil Shah

  • Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

    Dror S. Shouval;Dror S. Shouval;Amlan Biswas;Amlan Biswas;Jeremy A. Goettel;Jeremy A. Goettel;Katelyn McCann

  • Common variants at five new loci associated with early-onset inflammatory bowel disease.

    Marcin Imielinski;Robert N. Baldassano;Anne Griffiths;Richard K. Russell

  • Interleukin 10 receptor signaling: master regulator of intestinal mucosal homeostasis in mice and humans.

    Dror S. Shouval;Jodie Ouahed;Amlan Biswas;Jeremy A. Goettel

  • Clinical outcome in IL-10- and IL-10 receptor-deficient patients with or without hematopoietic stem cell transplantation.

    Karin R. Engelhardt;Neil Shah;Intan Faizura-Yeop;Dilara F. Kocacik Uygun

  • IL-10R polymorphisms are associated with very-early-onset ulcerative colitis

    Christopher J. Moran;Christopher J. Moran;Thomas D. Walters;Cong‐Hui Guo;Subra Kugathasan

  • Incidence, outcomes, and health services burden of very early onset inflammatory bowel disease.

    Eric I. Benchimol;David R. Mack;Geoffrey C. Nguyen;Scott B. Snapper

  • Eating disorders in adolescent boys: a review of the adolescent and young adult literature

    Aleixo M Muise;Debra G Stein;Gordon Arbess

  • Mutations in Tetratricopeptide Repeat Domain 7A Result in a Severe Form of Very Early Onset Inflammatory Bowel Disease

    Yaron Avitzur;Conghui Guo;Lucas A. Mastropaolo;Ehsan Bahrami

  • NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2

    Aleixo M Muise;Wei Xu;Cong-Hui Guo;Thomas D Walters

  • Interleukin 1β Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency

    Dror S. Shouval;Amlan Biswas;Amlan Biswas;Yu Hui Kang;Yu Hui Kang;Alexandra E. Griffith

  • Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease

    Walter H. A. Kahr;Fred G. Pluthero;Abdul Elkadri;Neil Warner

  • A eukaryotic transcriptional repressor with carboxypeptidase activity.

    Gong-Ping He;Aleixo Muise;Audrey Wu Li;Hyo-Sung Ro

  • Advances in Evaluation of Chronic Diarrhea in Infants

    Jay R Thiagarajah;Daniel S Kamin;Sari Acra;Jeffrey D Goldsmith

  • Polymorphisms in E-cadherin ( CDH1 ) result in a mis-localised cytoplasmic protein that is associated with Crohn’s disease

    Aleixo M Muise;Thomas D Walters;Wioletta K Glowacka;Anne M Griffiths

  • Clinical Genomics in Inflammatory Bowel Disease.

    Holm H. Uhlig;Aleixo M. Muise

  • Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases

    Yue Li;Marita Führer;Ehsan Bahrami;Piotr Socha

  • Defects in NADPH Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease.

    Patti Hayes;Sandeep Dhillon;Kim O’Neill;Cornelia Thoeni

  • Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread

    Mark A. Czuczman;Ramzi Fattouh;Jorik M. van Rijn;Veronica Canadien

  • Regulation of adipogenesis by a transcriptional repressor that modulates MAPK activation.

    Sung-Woo Kim;Aleixo M. Muise;Peter J. Lyons;Hyo-Sung Ro

Frequent Co-Authors

Scott B. Snapper
Scott B. Snapper Boston Children's Hospital
Anne M. Griffiths
Anne M. Griffiths University of Toronto
John H. Brumell
John H. Brumell University of Toronto
Mark S. Silverberg
Mark S. Silverberg University of Toronto
Christoph Klein
Christoph Klein Ludwig-Maximilians-Universität München
Dan Turner
Dan Turner Hebrew University of Jerusalem
Holm H. Uhlig
Holm H. Uhlig University of Oxford
Bruce H. Horwitz
Bruce H. Horwitz Harvard Medical School
David R. Mack
David R. Mack University of Ottawa
Dermot P.B. McGovern
Dermot P.B. McGovern Cedars-Sinai Medical Center

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