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John H. Brumell

John H. Brumell

D-Index & Metrics

Microbiology

D-Index
82
Citations
51761
World Ranking
1028
National Ranking
24

Overview

John H. Brumell is affiliated with the University of Toronto in Canada. Their research spans diverse areas of biochemistry, genetics, molecular biology, and medicine, emphasizing molecular and cell biology alongside immunology and epidemiology.

They have contributed extensively to the understanding of cellular processes such as autophagy and cellular transport, integrating these with studies on disease mechanisms. Their research topics include:

  • Cellular transport and secretion
  • Autophagy in Disease and Therapy
  • Vibrio bacteria research studies
  • Endoplasmic Reticulum Stress and Disease
  • Calcium signaling and nucleotide metabolism
  • Gut microbiota and health
  • Bacteriophages and microbial interactions

Their recent publications highlight significant contributions within high-impact journals. Selected papers include:

  • Functional genomic landscape of cancer-intrinsic evasion of killing by T cells, 2020, Nature
  • Plasma membrane integrity: implications for health and disease, 2021, BMC Biology
  • V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy, 2022, The Journal of Cell Biology
  • GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis, 2021, Science Advances
  • A glucose meter interface for point-of-care gene circuit-based diagnostics, 2021, Nature Communications

Brumell's publication record frequently appears in venues such as:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Advances
  • Autophagy
  • iScience

Collaboration forms a significant aspect of their work, with frequent co-authors including:

  • Taoyingnan Li
  • Brian Raught
  • Sergio Grinstein
  • Andrew M. Sydor
  • Hongxian Zhu

Their research contributions interface with multiple subfields such as molecular biology, cell biology, immunology, epidemiology, and physiology, reflecting a multidisciplinary approach to addressing biological and medical questions.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Autophagy Controls Salmonella Infection in Response to Damage to the Salmonella-containing Vacuole

    Cheryl L. Birmingham;Adam C. Smith;Malina A. Bakowski;Tamotsu Yoshimori

  • The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway

    Yiyu T. Zheng;Shahab Shahnazari;Andreas Brech;Trond Lamark

  • Salmonella pathogenicity islands: big virulence in small packages

    Sandra L. Marcus;John H. Brumell;Cheryl G. Pfeifer;B.Brett Finlay

  • Activation of antibacterial autophagy by NADPH oxidases

    Ju Huang;Veronica Canadien;Grace Y. Lam;Benjamin E. Steinberg

  • Bacteria–autophagy interplay: a battle for survival

    Ju Huang;John H. Brumell

  • The Syk Protein Tyrosine Kinase Is Essential for Fcγ Receptor Signaling in Macrophages and Neutrophils

    Friedemann Kiefer;John Brumell;Nadia Al-Alawi;Sylvain Latour

  • A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

    Daniel J Klionsky;Eric H. Baehrecke;John H. Brumell;Charleen T. Chu

  • Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

    Keith A. Lawson;Keith A. Lawson;Cristovão M. Sousa;Xiaoyu Zhang;Eiru Kim

  • Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles.

    Cheryl L Birmingham;Veronica Canadien;Natalia A Kaniuk;Benjamin E Steinberg

  • Recognition of Bacteria in the Cytosol of Mammalian Cells by the Ubiquitin System

    Andrew J Perrin;Xiuju Jiang;Cheryl L Birmingham;Nancy S.Y So

  • The many roles of NOX2 NADPH oxidase-derived ROS in immunity

    Grace Y. Lam;Ju Huang;John H. Brumell;John H. Brumell

  • Listeria monocytogenes evades killing by autophagy during colonization of host cells.

    Cheryl L. Birmingham;Veronica Canadien;Edith Gouin;Erin B. Troy

  • Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy

    Molly A. Lynch-Day;Deepali Bhandari;Shekar Menon;Ju Huang

  • The invasion-associated type III secretion system of Salmonella enterica serovar Typhimurium is necessary for intracellular proliferation and vacuole biogenesis in epithelial cells.

    Olivia Steele-Mortimer;John H Brumell;Leigh A Knodler;Stephane Méresse

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

Frequent Co-Authors

B. Brett Finlay
B. Brett Finlay University of British Columbia
Aleixo M. Muise
Aleixo M. Muise University of Toronto
Daniel J. Klionsky
Daniel J. Klionsky University of Michigan–Ann Arbor
Brian Raught
Brian Raught Princess Margaret Cancer Centre
Mark S. Silverberg
Mark S. Silverberg University of Toronto
Tamotsu Yoshimori
Tamotsu Yoshimori Osaka University
Sergio Lavandero
Sergio Lavandero University of Chile
Anne M. Griffiths
Anne M. Griffiths University of Toronto
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine

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