World's Best Scientists 2026 revealed!
Brian K. Coombes

Brian K. Coombes

D-Index & Metrics

Microbiology

D-Index
57
Citations
10639
World Ranking
3603
National Ranking
105

Brian K. Coombes publication distribution in Microbiology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Microbiology in 2026. The highlighted bar marks where Brian K. Coombes sits on this spectrum.

55–64 publications: 8 scientists 65–74 publications: 29 scientists 75–84 publications: 55 scientists 85–94 publications: 112 scientists 95–104 publications: 137 scientists 105–114 publications: 190 scientists 115–124 publications: 235 scientists 125–134 publications: 234 scientists 135–144 publications: 288 scientists 145–154 publications: 264 scientists 155–164 publications: 264 scientists 165–174 publications: 253 scientists 175–184 publications: 276 scientists 185–194 publications: 190 scientists 195–204 publications: 233 scientists 205–214 publications: 207 scientists 215–224 publications: 198 scientists 225–234 publications: 155 scientists 235–244 publications: 161 scientists 245–254 publications: 160 scientists 255–264 publications: 146 scientists 265–274 publications: 139 scientists 275–284 publications: 148 scientists 285–294 publications: 115 scientists 295–304 publications: 96 scientists 305–314 publications: 88 scientists 315–324 publications: 106 scientists 325–334 publications: 65 scientists 335–344 publications: 76 scientists 345–354 publications: 64 scientists 355–364 publications: 62 scientists 365–374 publications: 65 scientists 375–384 publications: 61 scientists 385–394 publications: 34 scientists 395–404 publications: 44 scientists 405–414 publications: 36 scientists 415–424 publications: 35 scientists 425–434 publications: 29 scientists 435–444 publications: 33 scientists 445–454 publications: 34 scientists 455–464 publications: 25 scientists 465–474 publications: 26 scientists 475–484 publications: 20 scientists 485–494 publications: 19 scientists 495–504 publications: 16 scientists 505–514 publications: 17 scientists 515–524 publications: 23 scientists 525–534 publications: 14 scientists 535–544 publications: 14 scientists 545–554 publications: 18 scientists 555–564 publications: 12 scientists 565–574 publications: 7 scientists 575–584 publications: 9 scientists 585–594 publications: 9 scientists 595–604 publications: 9 scientists 605–614 publications: 7 scientists 615–624 publications: 9 scientists 625–634 publications: 7 scientists 635–644 publications: 4 scientists 645–654 publications: 5 scientists 655–664 publications: 6 scientists 665–674 publications: 7 scientists 675–678 publications: 3 scientists 679+ publications: 99 scientists
55 publications 679+

This scientist: 130 publications — 17th percentile

17% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 679 publications or more.

Brian K. Coombes D-index placement in Microbiology in 2026

The chart shows the D-index (discipline H-index) distribution of Microbiology scientists ranked by Research.com in 2026. The highlighted bar marks where Brian K. Coombes sits on this spectrum.

40 D-Index: 30 scientists 41 D-Index: 86 scientists 42 D-Index: 90 scientists 43 D-Index: 117 scientists 44 D-Index: 122 scientists 45 D-Index: 123 scientists 46 D-Index: 108 scientists 47 D-Index: 110 scientists 48 D-Index: 106 scientists 49 D-Index: 109 scientists 50 D-Index: 129 scientists 51 D-Index: 111 scientists 52 D-Index: 116 scientists 53 D-Index: 127 scientists 54 D-Index: 134 scientists 55 D-Index: 134 scientists 56 D-Index: 111 scientists 57 D-Index: 136 scientists 58 D-Index: 162 scientists 59 D-Index: 151 scientists 60 D-Index: 139 scientists 61 D-Index: 122 scientists 62 D-Index: 126 scientists 63 D-Index: 144 scientists 64 D-Index: 109 scientists 65 D-Index: 103 scientists 66 D-Index: 124 scientists 67 D-Index: 112 scientists 68 D-Index: 103 scientists 69 D-Index: 131 scientists 70 D-Index: 93 scientists 71 D-Index: 93 scientists 72 D-Index: 96 scientists 73 D-Index: 92 scientists 74 D-Index: 80 scientists 75 D-Index: 66 scientists 76 D-Index: 87 scientists 77 D-Index: 60 scientists 78 D-Index: 73 scientists 79 D-Index: 59 scientists 80 D-Index: 57 scientists 81 D-Index: 55 scientists 82 D-Index: 47 scientists 83 D-Index: 77 scientists 84 D-Index: 50 scientists 85 D-Index: 45 scientists 86 D-Index: 42 scientists 87 D-Index: 41 scientists 88 D-Index: 32 scientists 89 D-Index: 38 scientists 90 D-Index: 35 scientists 91 D-Index: 34 scientists 92 D-Index: 27 scientists 93 D-Index: 26 scientists 94 D-Index: 33 scientists 95 D-Index: 22 scientists 96 D-Index: 37 scientists 97 D-Index: 22 scientists 98 D-Index: 21 scientists 99 D-Index: 22 scientists 100 D-Index: 30 scientists 101 D-Index: 16 scientists 102 D-Index: 20 scientists 103 D-Index: 17 scientists 104 D-Index: 19 scientists 105 D-Index: 16 scientists 106 D-Index: 19 scientists 107 D-Index: 18 scientists 108 D-Index: 14 scientists 109 D-Index: 10 scientists 110 D-Index: 9 scientists 111 D-Index: 7 scientists 112 D-Index: 11 scientists 113 D-Index: 6 scientists 114 D-Index: 15 scientists 115 D-Index: 10 scientists 116 D-Index: 12 scientists 117 D-Index: 7 scientists 118 D-Index: 10 scientists 119 D-Index: 10 scientists 120 D-Index: 11 scientists 121 D-Index: 2 scientists 122 D-Index: 7 scientists 123 D-Index: 12 scientists 124 D-Index: 5 scientists 125 D-Index: 9 scientists 126 D-Index: 6 scientists 127+ D-Index: 95 scientists
40 D-Index 127+

This scientist: 57 D-Index — 36th percentile

36% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 127 D-Index or more.

Overview

Brian K. Coombes is affiliated with McMaster University in Canada, focusing their research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields including Molecular Biology, Food Science, Molecular Medicine, Ecology, and Infectious Diseases.

Their research addresses multiple key topics, notably Gut microbiota and health, Antibiotic Resistance in Bacteria, Bacteriophages and microbial interactions, Salmonella and Campylobacter epidemiology, Escherichia coli research studies, RNA and protein synthesis mechanisms, and Probiotics and Fermented Foods.

Coombes has contributed to a number of publications across various venues. Frequent publication platforms include bioRxiv (Cold Spring Harbor Laboratory), Journal of the Canadian Association of Gastroenterology, Nature, Infection and Immunity, and Nature Microbiology.

Recent papers authored or co-authored by Coombes include:

  • Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling, 2020, Nature
  • Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii, 2023, Nature Chemical Biology
  • High-throughput fitness screening and transcriptomics identify a role for a type IV secretion system in the pathogenesis of Crohn's disease-associated Escherichia coli, 2021, Nature Communications
  • Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts, 2021, Nature Communications
  • Genetic and Chemical Screening in Human Blood Serum Reveals Unique Antibacterial Targets and Compounds against Klebsiella pneumoniae, 2020, Cell Reports

Coombes collaborates frequently with several co-authors, including Aline Fiebig-Comyn, Eric D. Brown, Jakob Magolan, Caressa N. Tsai, and Elena F. Verdú. These collaborations reflect ongoing interdisciplinary work within their research focus.

Best Publications

  • A draft genome of Yersinia pestis from victims of the Black Death

    Kirsten I. Bos;Verena J. Schuenemann;G. Brian Golding;Hernán A. Burbano

  • Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance

    Andrew M. King;Sarah A. Reid-Yu;Wenliang Wang;Dustin T. King

  • Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy

    Linda Ejim;Maya A Farha;Shannon B Falconer;Jan Wildenhain

  • Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance.

    Jonathan M. Stokes;Craig R. MacNair;Bushra Ilyas;Shawn French

  • Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii

    Unknown

  • Targeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black Death

    Verena J. Schuenemann;Kirsten I. Bos;Sharon DeWitte;Sarah Schmedes

  • Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics.

    Craig R. MacNair;Jonathan M. Stokes;Lindsey A. Carfrae;Aline A. Fiebig-Comyn

  • Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling.

    Elizabeth J. Culp;Nicholas Waglechner;Wenliang Wang;Aline A. Fiebig-Comyn

  • Expression and secretion of Salmonella pathogenicity island-2 virulence genes in response to acidification exhibit differential requirements of a functional type III secretion apparatus and SsaL.

    Brian K. Coombes;Nat F. Brown;Yanet Valdez;John H. Brumell

  • Molecular Analysis as an Aid To Assess the Public Health Risk of Non-O157 Shiga Toxin-Producing Escherichia coli Strains

    Brian K. Coombes;Brian K. Coombes;Mark E. Wickham;Mariola Mascarenhas;Samantha Gruenheid

  • Analysis of the Contribution of Salmonella Pathogenicity Islands 1 and 2 to Enteric Disease Progression Using a Novel Bovine Ileal Loop Model and a Murine Model of Infectious Enterocolitis

    Brian K. Coombes;Bryan A. Coburn;Andrew A. Potter;Susantha Gomis

  • Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4

    Joseph F. Cavallari;Morgan D. Fullerton;Brittany M. Duggan;Kevin P. Foley

  • Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes

    John H.E. Nash;Andre Villegas;Andrew M. Kropinski;Renan Aguilar-Valenzuela

  • Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis

    Cherrie-Lee N. Small;Sarah A. Reid-Yu;Joseph B. McPhee;Brian K. Coombes

  • Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine.

    Nat F Brown;Bruce A Vallance;Brian K Coombes;Yanet Valdez

  • Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis

    Mark S. Ladinsky;Leandro P. Araujo;Xiao Zhang;John Veltri

  • Identification of MEK- and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells.

    Brian K. Coombes;James B. Mahony

  • FimH Adhesin of Type 1 Fimbriae Is a Potent Inducer of Innate Antimicrobial Responses Which Requires TLR4 and Type 1 Interferon Signalling

    Ali A. Ashkar;Karen L. Mossman;Brian K. Coombes;Carlton L. Gyles

  • Bacterial genetic determinants of non-O157 STEC outbreaks and hemolytic-uremic syndrome after infection.

    Mark E. Wickham;Claudia Lupp;Mariola Mascarenhas;Alejandra Vazquez

  • Crossing the line: selection and evolution of virulence traits.

    Nat F Brown;Mark E Wickham;Brian K Coombes;B. Brett Finlay

  • Chlamydia pneumoniae infection of human endothelial cells induces proliferation of smooth muscle cells via an endothelial cell-derived soluble factor(s).

    Brian K. Coombes;James B. Mahony

Frequent Co-Authors

B. Brett Finlay
B. Brett Finlay University of British Columbia
James B. Mahony
James B. Mahony McMaster University
Eric D. Brown
Eric D. Brown McMaster University
Mohamed A. Karmali
Mohamed A. Karmali Public Health Agency of Canada
Colin Cooper
Colin Cooper University of East Anglia
Alexei Savchenko
Alexei Savchenko University of Calgary
José L. Puente
José L. Puente National Autonomous University of Mexico
Subash Sad
Subash Sad University of Ottawa
Gerard D. Wright
Gerard D. Wright McMaster University
John H. Brumell
John H. Brumell University of Toronto

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