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Yukihiko Shirayama

Yukihiko Shirayama

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Neuroscience 47 6378 5870 208 196 144 9812

Yukihiko Shirayama publications per year

The chart shows the history of publications by Yukihiko Shirayama between 1990 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Yukihiko Shirayama published across 36 years, from 1990 to 2025, averaging 4.1 papers a year. Output peaked at 10 publications in 2020. 4 of the 146 publications appeared in the last two years.

No. of publications
2 4 6 8 10
Bar chart. Horizontal axis: year, 1990 to 2025. Vertical axis: number of publications, 0 to 10. Peak 10 publications in 2020. 1990: 1 publication 1991: 1 publication 1992: 1 publication 1993: 3 publications 1994: 2 publications 1995: 0 publications 1996: 1 publication 1997: 1 publication 1998: 2 publications 1999: 3 publications 2000: 2 publications 2001: 5 publications 2002: 4 publications 2003: 2 publications 2004: 5 publications 2005: 7 publications 2006: 8 publications 2007: 5 publications 2008: 6 publications 2009: 6 publications 2010: 6 publications 2011: 5 publications 2012: 3 publications 2013: 5 publications 2014: 7 publications 2015: 9 publications 2016: 4 publications 2017: 7 publications 2018: 4 publications 2019: 3 publications 2020: 10 publications 2021: 6 publications 2022: 4 publications 2023: 4 publications 2024: 2 publications 2025: 2 publications
1990 2025

146 publications in total across all disciplines

View publications per year as a table
Yukihiko Shirayama: publications per year, 1990 to 2025
Year Publications
1990 1
1991 1
1992 1
1993 3
1994 2
1995 0
1996 1
1997 1
1998 2
1999 3
2000 2
2001 5
2002 4
2003 2
2004 5
2005 7
2006 8
2007 5
2008 6
2009 6
2010 6
2011 5
2012 3
2013 5
2014 7
2015 9
2016 4
2017 7
2018 4
2019 3
2020 10
2021 6
2022 4
2023 4
2024 2
2025 2
Total 146
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Yukihiko Shirayama publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Yukihiko Shirayama sits on this spectrum.

No. of scientists
100 200 300 400 500
Bar chart with 86 bars. Horizontal axis: publications, 38–47 to 887+. Vertical axis: number of scientists, 0 to 539. Most scientists, 539, have 98–107 publications. The last bar groups every scientist with 887 publications or more. The highlighted bar, 138–147 publications, is where this scientist sits. 38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientist 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38–47 publications 887+

This scientist: 144 publications — 40th percentile

40% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

View publications distribution as a table
Number of Neuroscience scientists by publication count, Research.com 2026 ranking edition. Based on 9,597 ranked scientists.
Publications Scientists This scientist
38–47 18
48–57 79
58–67 193
68–77 323
78–87 406
88–97 452
98–107 539
108–117 505
118–127 522
128–137 469
138–147 456 144
148–157 459
158–167 397
168–177 383
178–187 350
188–197 302
198–207 306
208–217 262
218–227 242
228–237 220
238–247 203
248–257 174
258–267 176
268–277 175
278–287 125
288–297 116
298–307 127
308–317 128
318–327 99
328–337 89
338–347 78
348–357 96
358–367 66
368–377 59
378–387 65
388–397 54
398–407 48
408–417 49
418–427 34
428–437 31
438–447 30
448–457 31
458–467 36
468–477 40
478–487 35
488–497 30
498–507 23
508–517 26
518–527 20
528–537 23
538–547 20
548–557 20
558–567 17
568–577 14
578–587 20
588–597 20
598–607 19
608–617 18
618–627 17
628–637 11
638–647 11
648–657 11
658–667 8
668–677 7
678–687 11
688–697 10
698–707 4
708–717 6
718–727 5
728–737 5
738–747 9
748–757 9
758–767 3
768–777 7
778–787 7
788–797 6
798–807 2
808–817 2
818–827 7
828–837 0
838–847 9
848–857 3
858–867 1
868–877 3
878–886 6
887+ 100
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Yukihiko Shirayama D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Yukihiko Shirayama sits on this spectrum.

No. of scientists
100 200 300 400 500
Bar chart with 68 bars. Horizontal axis: D-Index, 30–31 to 163+. Vertical axis: number of scientists, 0 to 512. Most scientists, 512, have 46–47 D-Index. The last bar groups every scientist with 163 D-Index or more. The highlighted bar, 46–47 D-Index, is where this scientist sits. 30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30–31 D-Index 163+

This scientist: 47 D-Index — 35th percentile

35% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

View D-Index distribution as a table
Number of Neuroscience scientists by D-index, Research.com 2026 ranking edition. Based on 9,597 ranked scientists.
D-Index Scientists This scientist
30–31 42
32–33 172
34–35 296
36–37 435
38–39 459
40–41 456
42–43 467
44–45 478
46–47 512 47
48–49 435
50–51 425
52–53 418
54–55 392
56–57 357
58–59 334
60–61 328
62–63 260
64–65 278
66–67 239
68–69 250
70–71 210
72–73 200
74–75 189
76–77 170
78–79 146
80–81 113
82–83 126
84–85 100
86–87 84
88–89 99
90–91 84
92–93 85
94–95 72
96–97 76
98–99 45
100–101 49
102–103 43
104–105 32
106–107 45
108–109 50
110–111 32
112–113 39
114–115 32
116–117 29
118–119 27
120–121 19
122–123 23
124–125 27
126–127 16
128–129 24
130–131 13
132–133 21
134–135 17
136–137 14
138–139 15
140–141 10
142–143 10
144–145 13
146–147 9
148–149 8
150–151 6
152–153 6
154–155 7
156–157 7
158–159 10
160–161 4
162 8
163+ 100
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Overview

Yukihiko Shirayama is affiliated with Teikyo University in Japan and has contributed extensively to research in neuroscience and medicine, with a particular focus on physiological and psychiatric aspects of brain function and disorders. Their work is situated within subfields including physiology, biological psychiatry, clinical psychology, behavioral neuroscience, and cellular and molecular neuroscience.

Their research encompasses several key topics such as tryptophan and brain disorders, stress responses and cortisol, diet and metabolism studies, treatment of major depression, autism spectrum disorder research, adipose tissue and metabolism, and neurotransmitter receptor influence on behavior.

Shirayama's research output features frequent publications in a variety of peer-reviewed journals, with notable venues including Scientific Reports, Behavioural Brain Research, Pharmacology Biochemistry and Behavior, Translational Psychiatry, and Neuropsychopharmacology Reports.

  • Essential role of microglial transforming growth factor-β1 in antidepressant actions of (R)-ketamine and the novel antidepressant TGF-β1, 2020, Translational Psychiatry
  • Prefrontal cortex infusion of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produces antidepressant-like effects in a rodent model of depression, 2020, Neuropsychopharmacology Reports
  • Beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, attenuates anxiety-related behavior in a rodent post-traumatic stress disorder model, 2020, Scientific Reports
  • Associations among autistic traits, cognitive and affective empathy, and personality traits in adults with autism spectrum disorder and no intellectual disability, 2022, Scientific Reports
  • Allopregnanolone induces antidepressant-like effects through BDNF-TrkB signaling independent from AMPA receptor activation in a rat learned helplessness model of depression, 2020, Behavioural Brain Research

Collaboration is a significant aspect of Shirayama's career, with frequent co-authors including Kenji Hashimoto, Yasunori Oda, Masaaki Iwata, Katsumasa Muneoka, and Masaomi Iyo. These co-authorships span over multiple publications, reflecting ongoing scientific partnerships in related areas of study.

Best Publications

  • Brain-Derived Neurotrophic Factor Produces Antidepressant Effects in Behavioral Models of Depression

    Yukihiko Shirayama;Andrew C.-H. Chen;Shin Nakagawa;David S. Russell

  • R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects

    Yang C;Shirayama Y;Shirayama Y;Zhang Jc;Ren Q

  • Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect

    Andrew C.-H Chen;Yukihiko Shirayama;Kyung-Ho Shin;Rachael L Neve

  • Correlation between plasma levels of glutamate, alanine and serine with severity of depression.

    Hideaki Mitani;Yukihiko Shirayama;Takeshi Yamada;Kazuhisa Maeda

  • Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects.

    Yukihiko Shirayama;Yukihiko Shirayama;Hisahito Ishida;Masaaki Iwata;Gen-i Hazama

  • Antidepressant effects of TrkB ligands on depression-like behavior and dendritic changes in mice after inflammation

    Ji-chun Zhang;Jin Wu;Yuko Fujita;Wei Yao;Wei Yao;Wei Yao

  • Neurochemistry of the Nucleus Accumbens and its Relevance to Depression and Antidepressant Action in Rodents

    Yukihiko Shirayama;Shigeyuki Chaki

  • Negative Correlation between Brain Glutathione Level and Negative Symptoms in Schizophrenia: A 3T 1H-MRS Study

    Daisuke Matsuzawa;Takayuki Obata;Yukihiko Shirayama;Hiroi Nonaka

  • Beta-hydroxybutyrate, an endogenic NLRP3 inflammasome inhibitor, attenuates stress-induced behavioral and inflammatory responses

    Takehiko Yamanashi;Masaaki Iwata;Naho Kamiya;Kyohei Tsunetomi

  • Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat.

    Yukihiko Shirayama;Hiroshi Mitsushio;Mizuo Takashima;Hironobu Ichikawa

  • Alterations in brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain regions of a learned helplessness rat model and the antidepressant effects of a TrkB agonist and antagonist.

    Yukihiko Shirayama;Chun Yang;Ji-chun Zhang;Qian Ren

  • High occupancy of sigma-1 receptors in the human brain after single oral administration of fluvoxamine: a positron emission tomography study using [11C]SA4503.

    Masatomo Ishikawa;Kiichi Ishiwata;Kenji Ishii;Yuichi Kimura

  • Plasma levels of homovanillic acid, 5-hydroxyindoleacetic acid and cortisol, and serotonin turnover in depressed patients.

    Hideaki Mitani;Yukihiko Shirayama;Takeshi Yamada;Ryuzou Kawahara

  • Correlation of plasma neurosteroid levels to the severity of negative symptoms in male patients with schizophrenia

    Yukihiko Shirayama;Kenji Hashimoto;Yoshio Suzuki;Teruhiko Higuchi

  • Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-Ketamine.

    Yukihiko Shirayama;Kenji Hashimoto

  • Minocycline attenuates hyperlocomotion and prepulse inhibition deficits in mice after administration of the NMDA receptor antagonist dizocilpine.

    Lin Zhang;Yukihiko Shirayama;Masaomi Iyo;Kenji Hashimoto

  • Specific metabolites in the medial prefrontal cortex are associated with the neurocognitive deficits in schizophrenia: a preliminary study.

    Yukihiko Shirayama;Takayuki Obata;Daisuke Matsuzawa;Hiroi Nonaka

  • AMPA Receptor Activation-Independent Antidepressant Actions of Ketamine Metabolite (S)-Norketamine.

    Chun Yang;Shizuka Kobayashi;Kazuhito Nakao;Chao Dong

  • Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies

    Chie Shimamoto;Tetsuo Ohnishi;Motoko Maekawa;Akiko Watanabe

  • Regional Differences in Brain-Derived Neurotrophic Factor Levels and Dendritic Spine Density Confer Resilience to Inescapable Stress

    Chun Yang;Chun Yang;Yukihiko Shirayama;Yukihiko Shirayama;Ji-chun Zhang;Ji-chun Zhang;Qian Ren;Qian Ren

  • Short communication Correlation between plasma levels of glutamate, alanine and serine with severity of depression

    Hideaki Mitani;Yukihiko Shirayama;Takeshi Yamada;Kazuhisa Maeda

Frequent Co-Authors

Kenji Hashimoto
Kenji Hashimoto Chiba University
Masaomi Iyo
Masaomi Iyo Chiba University
Yoshio Minabe
Yoshio Minabe Kanazawa University
Kiyohisa Takahashi
Kiyohisa Takahashi Shiga University of Medical Science
Morikuni Takigawa
Morikuni Takigawa Kagoshima University
Ronald S. Duman
Ronald S. Duman Yale University
Ichiro Sora
Ichiro Sora Kobe University
Akira Sawa
Akira Sawa Johns Hopkins University
Takeo Yoshikawa
Takeo Yoshikawa RIKEN Center for Brain Science
Nakao Iwata
Nakao Iwata Fujita Health University

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