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Neuroscience
Finland
2026

D-Index & Metrics

Neuroscience

D-Index
84
Citations
28038
World Ranking
1384
National Ranking
9

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Finland Leader Award
  • 2025 - Research.com Neuroscience in Finland Leader Award
  • 2023 - Research.com Neuroscience in Finland Leader Award
  • 2022 - Research.com Neuroscience in Finland Leader Award

Overview

Eero Castrén is affiliated with the University of Helsinki in Finland. Their research primarily focuses on the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology. Within these broader domains, Castrén's work has a significant emphasis on Cellular and Molecular Neuroscience, Molecular Biology, Cognitive Neuroscience, Biological Psychiatry, and Neurology.

The main topics explored in Castrén's research include Neuroscience and Neuropharmacology Research, Nerve Injury and Regeneration, Neurotransmitter Receptor Influence on Behavior, Receptor Mechanisms and Signaling, Tryptophan and Brain Disorders, Psychedelics and Drug Studies, and the Treatment of Major Depression.

Among their recent papers are the following:

  • Antidepressant drugs act by directly binding to TRKB neurotrophin receptors, 2021, Cell
  • Brain-Derived Neurotrophic Factor Signaling in Depression and Antidepressant Action, 2021, Biological Psychiatry
  • Psychedelics promote plasticity by directly binding to BDNF receptor TrkB, 2023, Nature Neuroscience
  • Psychedelics and Neural Plasticity: Therapeutic Implications, 2022, Journal of Neuroscience
  • Beyond the 5-HT2AReceptor: Classic and Nonclassic Targets in Psychedelic Drug Action, 2023, Journal of Neuroscience

Frequent co-authors working alongside Castrén include Plínio Casarotto, Juzoh Umemori, Caroline Biojone, Senem Merve Fred, and Antti Sajanti.

Castrén's publications are often found in venues such as bioRxiv (Cold Spring Harbor Laboratory), Stroke, Journal of Neuroscience, European Neuropsychopharmacology, and European Journal of Neuroscience.

Best Publications

  • The antidepressant fluoxetine restores plasticity in the adult visual cortex.

    José Fernando Maya Vetencourt;Alessandro Sale;Alessandro Viegi;Laura Baroncelli

  • The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity.

    Eero Castrén;Tomi Rantamäki

  • Activation of the TrkB Neurotrophin Receptor Is Induced by Antidepressant Drugs and Is Required for Antidepressant-Induced Behavioral Effects

    Tommi Saarelainen;Panu Hendolin;Guilherme Lucas;Eija Koponen

  • Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus.

    Mikko Sairanen;Guilherme Lucas;Patrik Ernfors;Maija Castrén

  • Role of neurotrophic factors in depression.

    Eero Castrén;Vootele Võikar;Tomi Rantamäki

  • Is mood chemistry

    Eero Castrén

  • Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons.

    Francisco Zafra;Eero Castren;Hans Thoenen;Dan Lindholm

  • Analysis of gene expression data using self‐organizing maps

    Petri Törönen;Mikko Kolehmainen;Garry Wong;Eero Castrén

  • Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex.

    Eero Castren;Francisco Zafra;Hans Thoenen;Dan Lindholm

  • Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

    Plinio C. Casarotto;Mykhailo Girych;Senem M. Fred;Vera Kovaleva

  • Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation.

    D Lindholm;E Castrén;R Kiefer;F Zafra

  • Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes

    F Zafra;D Lindholm;E Castren;J Hartikka

  • Psychedelics promote plasticity by directly binding to BDNF receptor TrkB

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  • Serotonin and neuroplasticity - Links between molecular, functional and structural pathophysiology in depression.

    Christoph Kraus;Eero Castrén;Siegfried Kasper;Rupert Lanzenberger

  • Fear Erasure in Mice Requires Synergy Between Antidepressant Drugs and Extinction Training

    Nina N. Karpova;Anouchka Pickenhagen;Jesse Lindholm;Ettore Tiraboschi

  • BRAIN-DERIVED NEUROTROPHIC FACTOR PROTECTS AGAINST ISCHEMIC CELL DAMAGE IN RAT HIPPOCAMPUS

    Thomas Beck;Dan Lindholm;Eero Castrén;Andreas Wree

  • Brain-Derived Neurotrophic Factor Signaling in Depression and Antidepressant Action.

    Eero Castrén;Lisa M. Monteggia

  • The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus.

    Eero Castrén;Mervi Pitkänen;Jouni Sirviö;Alexander Parsadanian

  • Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain--implications for neuronal plasticity.

    Dan Lindholm;Eero Castrén;Maria Berzaghi;Andrea Blöchl

  • Pharmacologically Diverse Antidepressants Rapidly Activate Brain-Derived Neurotrophic Factor Receptor TrkB and Induce Phospholipase-Cγ Signaling Pathways in Mouse Brain

    Tomi Rantamäki;Panu Hendolin;Aino Kankaanpää;Jelena Mijatovic

  • Neurotrophic effects of antidepressant drugs.

    Eero Castrén

  • Brain-derived neurotrophic factor in mood disorders and antidepressant treatments.

    Eero Castrén;Masami Kojima

Frequent Co-Authors

Hans Thoenen
Hans Thoenen Max Planck Society
Sari E. Lauri
Sari E. Lauri University of Helsinki
Tomi Taira
Tomi Taira University of Helsinki
Mart Saarma
Mart Saarma University of Helsinki
Lamberto Maffei
Lamberto Maffei National Research Council (CNR)
Juha Kere
Juha Kere Karolinska Institute
Heikki Tanila
Heikki Tanila University of Eastern Finland
Satu Palva
Satu Palva University of Helsinki
Benedikt Berninger
Benedikt Berninger King's College London
Claudio Rivera
Claudio Rivera University of Helsinki

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