D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 53 Citations 11,261 115 World Ranking 11496 National Ranking 221

Research.com Recognitions

Awards & Achievements

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cell membrane
  • Biochemistry

Carlos G. Dotti mainly investigates Cell biology, Hippocampal formation, Axon, Membrane protein and Golgi apparatus. His studies in Cell biology integrate themes in fields like Molecular biology, Endocytic cycle and Cell polarity. His study in Hippocampal formation is interdisciplinary in nature, drawing from both Cell culture, Hippocampus, MRNA transport and Amyloid precursor protein.

His study looks at the relationship between Amyloid precursor protein and topics such as Cholesterol 24-hydroxylase, which overlap with Alzheimer's disease. His studies deal with areas such as Neurite and Neuron as well as Axon. His research integrates issues of Actin cytoskeleton, Profilin, Glutamate receptor, Dendritic spine and Neurotransmitter receptor in his study of Neuron.

His most cited work include:

  • Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. (1055 citations)
  • The Role of Local Actin Instability in Axon Formation (464 citations)
  • Chemical stimulation of synaptosomes modulates alpha -Ca2+/calmodulin-dependent protein kinase II mRNA association to polysomes. (343 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Neuroscience, Hippocampal formation, Neuron and Neurite. His biological study spans a wide range of topics, including Membrane protein, Amyloid precursor protein and Cell polarity. The various areas that Carlos G. Dotti examines in his Neuroscience study include Synaptic plasticity, Cholesterol, Fragile X syndrome and MAPK/ERK pathway.

His Hippocampal formation research includes themes of Hippocampus, Gene isoform and Biochemistry. Carlos G. Dotti combines subjects such as Cell culture and Actin remodeling of neurons with his study of Neuron. His research integrates issues of Biophysics, Cellular differentiation and Cytoskeleton in his study of Neurite.

He most often published in these fields:

  • Cell biology (78.91%)
  • Neuroscience (32.65%)
  • Hippocampal formation (28.57%)

What were the highlights of his more recent work (between 2015-2020)?

  • Cell biology (78.91%)
  • Hippocampal formation (28.57%)
  • Synaptic plasticity (8.16%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cell biology, Hippocampal formation, Synaptic plasticity, Neuroscience and Long-term potentiation. His biological study spans a wide range of topics, including Brain-derived neurotrophic factor, Drosophila and Energy metabolism. He has included themes like Vesicular transport protein, Cell membrane, Amyloidosis, Hippocampus and Gene isoform in his Hippocampal formation study.

Carlos G. Dotti interconnects Kinase and Long-term depression in the investigation of issues within Synaptic plasticity. His studies in Neuroscience integrate themes in fields like Alzheimer's disease and Neurotransmission. Carlos G. Dotti works mostly in the field of Long-term potentiation, limiting it down to concerns involving Transgene and, occasionally, Neurogenesis, Neuroinflammation, Memory impairment, Type 2 diabetes and Diabetes mellitus.

Between 2015 and 2020, his most popular works were:

  • PTEN recruitment controls synaptic and cognitive function in Alzheimer's models (74 citations)
  • Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons. (49 citations)
  • Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons (26 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Biochemistry
  • Cell membrane

His primary scientific interests are in Long-term potentiation, Synaptic plasticity, Biochemistry, Cell biology and Brain-derived neurotrophic factor. His Long-term potentiation research incorporates themes from Alzheimer's disease, Neurogenesis, Neuroscience and Molecular neuroscience. His studies deal with areas such as Postsynaptic potential and Neurotransmission as well as Synaptic plasticity.

The concepts of his Biochemistry study are interwoven with issues in Hippocampal formation and Neurodegeneration. Carlos G. Dotti combines Cell biology and HDAC4 in his studies. The Brain-derived neurotrophic factor study combines topics in areas such as Cellular differentiation, EZH2, Repressor and Premovement neuronal activity.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons.

Mikael Simons;Patrick Keller;Bart De Strooper;Konrad Beyreuther.
Proceedings of the National Academy of Sciences of the United States of America (1998)

1496 Citations

The Role of Local Actin Instability in Axon Formation

Frank Bradke;Carlos G. Dotti.
Science (1999)

716 Citations

Chemical stimulation of synaptosomes modulates alpha -Ca2+/calmodulin-dependent protein kinase II mRNA association to polysomes.

Claudia Bagni;Liliana Mannucci;Carlos G. Dotti;Francesco Amaldi.
The Journal of Neuroscience (2000)

524 Citations

Axonal Membrane Proteins Are Transported in Distinct Carriers: A Two-Color Video Microscopy Study in Cultured Hippocampal Neurons

Christoph Kaether;Paul Skehel;Carlos G. Dotti.
Molecular Biology of the Cell (2000)

367 Citations

Axonal and dendritic endocytic pathways in cultured neurons.

Robert G. Parton;Kai Simons;Carlos G. Dotti.
Journal of Cell Biology (1992)

352 Citations

Microtubule-dependent recruitment of Staufen-green fluorescent protein into large RNA-containing granules and subsequent dendritic transport in living hippocampal neurons.

Martin Köhrmann;Ming Luo;Christoph Kaether;Luc DesGroseillers.
Molecular Biology of the Cell (1999)

349 Citations

Neuronal polarity: essential role of protein-lipid complexes in axonal sorting.

Maria Dolores Ledesma;Kai Simons;Carlos G. Dotti.
Proceedings of the National Academy of Sciences of the United States of America (1998)

324 Citations

The mammalian Staufen protein localizes to the somatodendritic domain of cultured hippocampal neurons: Implications for its involvement in mRNA transport

Michael A. Kiebler;Indradeo Hemraj;Paul Verkade;Martin Köhrmann.
The Journal of Neuroscience (1999)

324 Citations

Neuronal Polarity: Vectorial Cytoplasmic Flow Precedes Axon Formation

Frank Bradke;Carlos G Dotti.
Neuron (1997)

313 Citations

Polarized sorting of glypiated proteins in hippocampal neurons.

Carlos G. Dotti;Robert G. Parton;Kai Simons.
Nature (1991)

308 Citations

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