What is he best known for?
The fields of study he is best known for:
His main research concerns Molecular biology, RNA-binding protein, RNA, Cell biology and MRNA transport.
Luc DesGroseillers has researched Molecular biology in several fields, including Gene expression, Virology, Murine leukemia virus, Virus and Gene.
His biological study spans a wide range of topics, including Hippocampal formation, Microtubule and Green fluorescent protein.
His Cell biology research incorporates themes from Ribonucleoprotein, Messenger RNA, RNA splicing, Cytoskeleton and Gene isoform.
His Messenger RNA study combines topics in areas such as Ribosome and Ribosomal protein.
His MRNA transport study incorporates themes from Translational regulation, Nocodazole, P-bodies, Dendritic transport and RNA silencing.
His most cited work include:
- Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay. (395 citations)
- Microtubule-dependent recruitment of Staufen-green fluorescent protein into large RNA-containing granules and subsequent dendritic transport in living hippocampal neurons. (266 citations)
- Characterization of an RNA Granule from Developing Brain (226 citations)
What are the main themes of his work throughout his whole career to date?
Luc DesGroseillers spends much of his time researching Molecular biology, Cell biology, RNA, Messenger RNA and RNA-binding protein.
His study in Molecular biology is interdisciplinary in nature, drawing from both Complementary DNA, Peptide sequence, Gene expression, Gene and Virology.
He interconnects Ribonucleoprotein, Translation, MRNA transport, Cell cycle and Ribosome in the investigation of issues within Cell biology.
In his study, Spindle apparatus and Mitosis is strongly linked to Nucleolus, which falls under the umbrella field of RNA.
His Messenger RNA research is multidisciplinary, incorporating elements of Neurite and Transfection.
His research in RNA-binding protein tackles topics such as Microtubule which are related to areas like Cytoskeleton.
He most often published in these fields:
- Molecular biology (45.22%)
- Cell biology (42.61%)
- RNA (20.87%)
What were the highlights of his more recent work (between 2007-2021)?
- Cell biology (42.61%)
- RNA (20.87%)
- Ribonucleoprotein (11.30%)
In recent papers he was focusing on the following fields of study:
Luc DesGroseillers mainly focuses on Cell biology, RNA, Ribonucleoprotein, Molecular biology and RNA-binding protein.
His work carried out in the field of Cell biology brings together such families of science as Translation, Cell cycle, Dendritic spine and Synaptic plasticity.
His RNA study combines topics from a wide range of disciplines, such as Novel protein, MRNA transport and Gene isoform.
His Ribonucleoprotein research also works with subjects such as
- Immunoprecipitation which is related to area like Cytoplasm, Gene silencing, Virus, Virology and Stress granule,
- Gene knockdown which connect with Metabotropic glutamate receptor and Hippocampal formation.
His Molecular biology research includes elements of Ribosomal RNA, Synapse and Messenger RNA.
His studies in RNA-binding protein integrate themes in fields like Binding protein, Alternative splicing, Protein family, Microtubule and Messenger RNP.
Between 2007 and 2021, his most popular works were:
- Novel Staufen1 ribonucleoproteins prevent formation of stress granules but favour encapsidation of HIV-1 genomic RNA. (90 citations)
- The RNA-binding protein Staufen1 is increased in DM1 skeletal muscle and promotes alternative pre-mRNA splicing (85 citations)
- Forskolin induction of late-LTP and up-regulation of 5′ TOP mRNAs translation via mTOR, ERK, and PI3K in hippocampal pyramidal cells (72 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Cell biology, Synaptic plasticity, Long-term potentiation, RNA and Ribonucleoprotein.
His research in Cell biology is mostly focused on Subcellular localization.
As part of the same scientific family, Luc DesGroseillers usually focuses on Synaptic plasticity, concentrating on PI3K/AKT/mTOR pathway and intersecting with Pyramidal cell, Forskolin, Translation and MAPK/ERK pathway.
His research in Long-term potentiation focuses on subjects like Neuroscience, which are connected to Gene knockdown, Metabotropic glutamate receptor and Messenger RNA.
RNA is a primary field of his research addressed under Genetics.
His Ribonucleoprotein research integrates issues from Immunoprecipitation, Polysome, splice, Stress granule and Binding site.
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