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Luc DesGroseillers

Luc DesGroseillers

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
14051
World Ranking
15976
National Ranking
556

Overview

Luc DesGroseillers is affiliated with the University of Montreal in Canada and conducts research primarily in the fields of Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields, with a strong focus on Molecular Biology, Cancer Research, and smaller contributions to Virology, Electrical and Electronic Engineering, and Immunology.

Their research topics cover diverse aspects of RNA biology and cancer-related mechanisms, including:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • RNA and protein synthesis mechanisms
  • RNA Interference and Gene Delivery
  • Cancer-related molecular mechanisms research
  • Molecular Biology Techniques and Applications

Luc DesGroseillers has contributed to a series of papers published in notable scientific journals. Recent publications include:

  • "The Staufen1-dependent cell cycle regulon or how a misregulated RNA-binding protein leads to cancer" (2021) in Biological reviews/Biological reviews of the Cambridge Philosophical Society
  • "Staufen1 localizes to the mitotic spindle and controls the localization of RNA populations to the spindle" (2020) in Journal of Cell Science
  • "Staufen1 is Essential for Cell-Cycle Transitions and Cell Proliferation Via the Control of E2F1 Expression" (2020) in Journal of Molecular Biology
  • "The double-stranded RNA-binding protein, Staufen1, is an IRES-transacting factor regulating HIV-1 cap-independent translation initiation" (2021) in Nucleic Acids Research
  • "High Level of Staufen1 Expression Confers Longer Recurrence Free Survival to Non-Small Cell Lung Cancer Patients by Promoting THBS1 mRNA Degradation" (2021) in International Journal of Molecular Sciences

The scientist frequently publishes in specific venues, including:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • International Journal of Molecular Sciences
  • Nucleic Acids Research
  • Biological reviews/Biological reviews of the Cambridge Philosophical Society
  • Journal of Cell Science

Among frequent coauthors, the following researchers have collaborated most often with Luc DesGroseillers:

  • Florence Bonnet-Magnaval
  • Sami Hassine
  • Bellastrid Doran
  • Mehdi Ghram
  • Yulemi Gónzalez Quesada

Best Publications

  • Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay.

    Yoon Ki Kim;Luc Furic;Luc DesGroseillers;Lynne E. Maquat

  • Microtubule-dependent recruitment of Staufen-green fluorescent protein into large RNA-containing granules and subsequent dendritic transport in living hippocampal neurons.

    Martin Köhrmann;Ming Luo;Christoph Kaether;Luc DesGroseillers

  • Characterization of an RNA Granule from Developing Brain

    George Elvira;Sylwia Wasiak;Vanessa Blandford;Xin-Kang Tong

  • Mammalian Staufen Is a Double-Stranded-RNA- and Tubulin-Binding Protein Which Localizes to the Rough Endoplasmic Reticulum

    Louise Wickham;Thomas Duchaîne;Ming Luo;Ivan R. Nabi

  • Specific microsatellite loci for brook charr reveal strong population subdivision on a microgeographic scale

    B. Angers;L. Bernatchez;A. Angers;L. Desgroseillers

  • Thymotropism of murine leukemia virus is conferred by its long terminal repeat.

    L DesGroseillers;E Rassart;P Jolicoeur

  • Staufen1 regulates diverse classes of mammalian transcripts.

    Yoon Ki Kim;Luc Furic;Marc Parisien;François Major

  • Molecular insights into mRNA transport and local translation in the mammalian nervous system.

    Michael A Kiebler;Luc DesGroseillers

  • The Double-Stranded RNA-Binding Protein Staufen Is Incorporated in Human Immunodeficiency Virus Type 1: Evidence for a Role in Genomic RNA Encapsidation

    Andrew J. Mouland;Johanne Mercier;Ming Luo;Luc Bernier

  • Interaction of Staufen1 with the 5′ end of mRNA facilitates translation of these RNAs

    Samuel Dugré-Brisson;George Elvira;Karine Boulay;Laurent Chatel-Chaix

  • Physical mapping of the Fv-1 tropism host range determinant of BALB/c murine leukemia viruses.

    L DesGroseillers;P Jolicoeur

  • The tandem direct repeats within the long terminal repeat of murine leukemia viruses are the primary determinant of their leukemogenic potential.

    L DesGroseillers;P Jolicoeur

  • Pex mRNA is localized in developing mouse osteoblasts and odontoblasts.

    Andréa Frota Ruchon;Mieczyslaw Marcinkiewicz;Géraldine Siegfried;Harriet S. Tenenhouse

  • Intracellular trafficking of RNA in neurons.

    Wayne S. Sossin;Luc DesGroseillers

  • Staufen2 isoforms localize to the somatodendritic domain of neurons and interact with different organelles

    Thomas F. Duchaîne;Indradeo Hemraj;Luc Furic;Anke Deitinghoff

  • Identification of Staufen in the human immunodeficiency virus type 1 Gag ribonucleoprotein complex and a role in generating infectious viral particles.

    Laurent Chatel-Chaix;Jean-Francois Clément;Jean-Francois Clément;Catherine Martel;Véronique Bériault

  • Declining expression of neprilysin in Alzheimer disease vasculature: possible involvement in cerebral amyloid angiopathy.

    Mélanie Carpentier;Yves Robitaille;Luc DesGroseillers;Guy Boileau

  • A genome-wide approach identifies distinct but overlapping subsets of cellular mRNAs associated with Staufen1- and Staufen2-containing ribonucleoprotein complexes.

    Luc Furic;Marjolaine Maher-Laporte;Luc DesGroseillers

  • Multiple serotonergic mechanisms contributing to sensitization in aplysia: evidence of diverse serotonin receptor subtypes.

    Demian Barbas;Luc DesGroseillers;Vincent F. Castellucci;Thomas J. Carew

  • Novel Staufen1 ribonucleoproteins prevent formation of stress granules but favour encapsidation of HIV-1 genomic RNA.

    Levon G. Abrahamyan;Laurent Chatel-Chaix;Laurent Chatel-Chaix;Lara Ajamian;Lara Ajamian;Miroslav P. Milev;Miroslav P. Milev

Frequent Co-Authors

Andrew J. Mouland
Andrew J. Mouland McGill University
Wayne S. Sossin
Wayne S. Sossin Montreal Neurological Institute and Hospital
Paul Jolicoeur
Paul Jolicoeur University of Montreal
Vincent F. Castellucci
Vincent F. Castellucci University of Montreal
Jean-Claude Lacaille
Jean-Claude Lacaille University of Montreal
Éric A. Cohen
Éric A. Cohen University of Montreal
Bernard J. Jasmin
Bernard J. Jasmin University of Ottawa
Keith K. Murai
Keith K. Murai McGill University Health Centre
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Ivan R. Nabi
Ivan R. Nabi University of British Columbia

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