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D-Index & Metrics

Medicine

D-Index
96
Citations
60754
World Ranking
9463
National Ranking
4883

Overview

Mark T. Keating is affiliated with Yarrow Biotechnology in the United States and focuses primarily on medical research with a multidisciplinary approach incorporating nephrology, bioengineering, molecular biology, epidemiology, and surgery. Their work covers several interconnected areas within medicine, particularly emphasizing renal function, acid-base balance, and monitoring technologies.

The scientist's main fields of study include:

  • Medicine

Key subfields explored in their research encompass:

  • Nephrology
  • Bioengineering
  • Molecular Biology
  • Epidemiology
  • Surgery

Mark T. Keating's research contributions prominently address these topics:

  • Renal function and acid-base balance
  • Analytical Chemistry and Sensors
  • Ion Transport and Channel Regulation
  • Sepsis Diagnosis and Treatment
  • Hemodynamic Monitoring and Therapy
  • Dialysis and Renal Disease Management
  • Complement system in diseases

The body of published work includes papers in diverse journals such as the ACS Sensors, Journal of Clinical Monitoring and Computing, and Haematologica. Notable recent publications are:

  • "Transcutaneous Flexible Sensor for In Vivo Photonic Detection of pH and Lactate" (2022) in ACS Sensors
  • "Clinical evaluation of a novel subcutaneous lactate monitor" (2021) in Journal of Clinical Monitoring and Computing
  • "Tesidolumab (LFG316) for treatment of C5-variant patients with paroxysmal nocturnal hemoglobinuria" (2022) in Haematologica

Mark T. Keating has collaborated frequently with several researchers in the field. Coauthors with multiple joint publications include:

  • Samir Shreim
  • John Weidling
  • Elliot L. Botvinick
  • Dat Nguyen
  • Micah M. Lawrence

Their research integrates analytical methods and clinical evaluations, particularly to improve monitoring and treatment approaches for metabolic and hematological conditions associated with renal and systemic diseases.

Best Publications

  • A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

    Michael C Sanguinetti;Changan Jiang;Mark E Curran;Mark T Keating

  • Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

    Qiuyun Chen;Glenn E. Kirsch;Danmei Zhang;Ramon Brugada

  • Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias.

    Q. Wang;M. E. Curran;I. Splawski;T. C. Burn

  • Genotype-Phenotype Correlation in the Long-QT Syndrome Gene-Specific Triggers for Life-Threatening Arrhythmias

    Peter J. Schwartz;Silvia G Priori;Carla Spazzolini;Arthur J Moss

  • Heart Regeneration in Zebrafish

    Kenneth D. Poss;Lindsay G. Wilson;Mark T. Keating

  • Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel.

    Sanguinetti Mc;Curran Me;Zou A;Shen J

  • SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

    Qing Kenneth Wang;Jiaxiang Shen;Jiaxiang Shen;Igor Splawski;Donald Atkinson;Donald Atkinson

  • Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.

    Igor Splawski;Katherine W. Timothy;Leah M. Sharpe;Niels Decher

  • MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia

    Geoffrey W Abbott;Federico Sesti;Igor Splawski;Marianne E Buck

  • Spectrum of Mutations in Long-QT Syndrome Genes KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

    Igor Splawski;Jiaxiang Shen;Katherine W. Timothy;Michael H. Lehmann

  • Genotype-Phenotype Correlation in the Long-QT Syndrome

    Peter J. Schwartz;Silvia G. Priori;Carla Spazzolini;Arthur J. Moss

  • Hemizygosity at the elastin locus in a developmental disorder, Williams syndrome

    Ewart Ak;Morris Ca;Atkinson D;Jin W

  • Molecular and cellular mechanisms of cardiac arrhythmias.

    Mark T. Keating;Michael C. Sanguinetti

  • Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate : implications for gene-specific therapy

    Peter J. Schwartz;Silvia G. Priori;Emanuela H. Locati;Carlo Napolitano

  • Actin mutations in dilated cardiomyopathy, a heritable form of heart failure

    Mark T. Keating;Thomas M. Olson

  • Mutations in the hminK gene cause long QT syndrome and suppress IKs function.

    Igor Splawski;Martin Tristani-Firouzi;Michael H. Lehmann;Michael C. Sanguinetti

  • Elastin is an essential determinant of arterial morphogenesis

    Dean Y. Li;Benjamin Brooke;Elaine C. Davis;Robert P. Mecham

  • Influence of the Genotype on the Clinical Course of the Long-QT Syndrome

    W Zareba;A J Moss;P J Schwartz;P J Schwartz;G M Vincent

  • The Spectrum of Symptoms and QT Intervals in Carriers of the Gene for the Long-QT Syndrome

    G. Michael Vincent;G. Michael Vincent;Katherine W. Timothy;Mark Leppert;Mark Keating

  • LIM-kinase1 Hemizygosity Implicated in Impaired Visuospatial Constructive Cognition

    J.Michael Frangiskakis;Amanda K Ewart;Colleen A Morris;Carolyn B Mervis

Frequent Co-Authors

Michael C. Sanguinetti
Michael C. Sanguinetti University of Utah
Peter J. Schwartz
Peter J. Schwartz Istituto Auxologico Italiano
Silvia G. Priori
Silvia G. Priori University of Pavia
Arthur J. Moss
Arthur J. Moss University of Rochester Medical Center
Kenneth D. Poss
Kenneth D. Poss Duke University
jeffrey a towbin
jeffrey a towbin St. Jude Children's Research Hospital
Carlo Napolitano
Carlo Napolitano University of Pavia
Mark Leppert
Mark Leppert University of Utah
Wojciech Zareba
Wojciech Zareba University of Rochester Medical Center
Felix B. Engel
Felix B. Engel University of Erlangen-Nuremberg

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