David J. Tester

Overview

Best Publications

• Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability

  Julie M. Cunningham;Eric R. Christensen;David J. Tester;Cheong Yong Kim

  1237
  Citations

• An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing.

  Jamie D. Kapplinger;David J. Tester;Marielle Alders;Begoña Benito

  809
  Citations

• Compendium of Cardiac Channel Mutations in 541 Consecutive Unrelated Patients Referred for Long QT Syndrome Genetic Testing

  David J. Tester;Melissa L. Will;Carla M. Haglund;Michael J. Ackerman

  797
  Citations

• Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1.

  Stephen N. Thibodeau;Amy J. French;Julie M. Cunningham;David Tester

  753
  Citations

• Mutant Caveolin-3 Induces Persistent Late Sodium Current and Is Associated With Long-QT Syndrome

  Matteo Vatta;Michael J. Ackerman;Bin Ye;Jonathan C. Makielski

  715
  Citations

• Altered Expression of hMSH2 and hMLH1 in Tumors with Microsatellite Instability and Genetic Alterations in Mismatch Repair Genes

  Stephen N. Thibodeau;Amy J. French;Patrick C. Roche;Julie M. Cunningham

  686
  Citations

• Postmortem molecular analysis of SCN5A defects in sudden infant death syndrome.

  Michael J. Ackerman;Benjamin L. Siu;William Q. Sturner;David J. Tester

  631
  Citations

• Postmortem long QT syndrome genetic testing for sudden unexplained death in the young.

  David J. Tester;Michael J. Ackerman

  499
  Citations

• Most LQT2 Mutations Reduce Kv11.1 (hERG) Current by a Class 2 (Trafficking-Deficient) Mechanism

  Corey L. Anderson;Brian P. Delisle;Blake D. Anson;Jennifer A. Kilby

  481
  Citations

• Spectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic test.

  Jamie D. Kapplinger;David J. Tester;Benjamin A. Salisbury;Janet L. Carr

  469
  Citations

• Syntrophin mutation associated with long QT syndrome through activation of the nNOS–SCN5A macromolecular complex

  Kazuo Ueda;Carmen Valdivia;Argelia Medeiros-Domingo;David J. Tester

  457
  Citations

• SCN4B-Encoded Sodium Channel β4 Subunit in Congenital Long-QT Syndrome

  Argelia Medeiros-Domingo;Toshihiko Kaku;David J. Tester;Pedro Iturralde-Torres

  456
  Citations

• The RYR2-Encoded Ryanodine Receptor/Calcium Release Channel in Patients Diagnosed Previously With Either Catecholaminergic Polymorphic Ventricular Tachycardia or Genotype Negative, Exercise-Induced Long QT Syndrome A Comprehensive Open Reading Frame Mutational Analysis

  Argelia Medeiros-Domingo;Zahurul A. Bhuiyan;David J. Tester;Nynke Hofman

  439
  Citations

• The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas.

  Julie M. Cunningham;Cheong Yong Kim;Eric R. Christensen;David J. Tester

  427
  Citations

• Mutation of an A-kinase-anchoring protein causes long-QT syndrome

  Lei Chen;Michelle L. Marquardt;David J. Tester;Kevin J. Sampson

  416
  Citations

• Spectrum and prevalence of cardiac sodium channel variants among black, white, Asian, and Hispanic individuals: implications for arrhythmogenic susceptibility and Brugada/long QT syndrome genetic testing.

  Michael J. Ackerman;Igor Splawski;Jonathan C. Makielski;David J. Tester

  408
  Citations

• Spectrum and Frequency of Cardiac Channel Defects in Swimming-Triggered Arrhythmia Syndromes

  Grace Choi;Laura J. Kopplin;David J. Tester;Melissa L. Will

  375
  Citations

• Genetic Testing for Long-QT Syndrome Distinguishing Pathogenic Mutations From Benign Variants

  Suraj Kapa;David J. Tester;Benjamin A. Salisbury;Carole Harris-Kerr

  372
  Citations

• Novel NOTCH1 mutations in patients with bicuspid aortic valve disease and thoracic aortic aneurysms.

  Stephen H. McKellar;David J. Tester;Marineh Yagubyan;Ramanath Majumdar

  335
  Citations

• Ethnic differences in cardiac potassium channel variants: implications for genetic susceptibility to sudden cardiac death and genetic testing for congenital long QT syndrome.

  Michael J. Ackerman;David J. Tester;Gregg S. Jones;Melissa L. Will

  333
  Citations