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Stephen N. Thibodeau

Stephen N. Thibodeau

D-Index & Metrics

Medicine

D-Index
136
Citations
89636
World Ranking
1947
National Ranking
1107

Overview

Stephen N. Thibodeau is affiliated with the Mayo Clinic in the United States and has an extensive publication record primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research contributions encompass significant subfields including Pathology and Forensic Medicine, Genetics, Oncology, Cancer Research, and Molecular Biology.

The scientist's research focuses on key topics such as genetic factors in colorectal cancer, genetic associations and epidemiology, colorectal cancer screening and detection, cancer genomics and diagnostics, prostate cancer treatment and research, colorectal cancer treatments and studies, and liver disease diagnosis and treatment.

They have published frequently in a variety of venues, including:

  • UNC Libraries
  • Nature Communications
  • Cancer Research
  • Cancer Epidemiology Biomarkers & Prevention
  • The American Journal of Human Genetics

Notable recent papers include:

  • Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis, 2020, Nature Communications
  • Genomic data in the All of Us Research Program, 2024, Nature
  • An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk, 2020, Nature Communications
  • Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk, 2020, The American Journal of Human Genetics
  • Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival, 2020, Nature Communications

Stephen N. Thibodeau collaborates frequently with a group of researchers who have coauthored numerous publications alongside them. These frequent coauthors include:

  • Polly A. Newcomb
  • Mark A. Jenkins
  • Steven Gallinger
  • Graham G. Giles
  • Loïc Le Marchand

Best Publications

  • Microsatellite instability in cancer of the proximal colon

    S. N. Thibodeau;G. Bren;D. Schaid

  • A National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer

    C. Richard Boland;Stephen N. Thibodeau;Stanley R. Hamilton;David Sidransky

  • REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

    Nilah M M. Ioannidis;Joseph H H. Rothstein;Joseph H H. Rothstein;Vikas Pejaver;Sumit Middha

  • Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

    Christine M. Ribic;Daniel J. Sargent;Malcolm J. Moore;Malcolm J. Moore;Stephen N. Thibodeau

  • APC mutations occur early during colorectal tumorigenesis.

    Steven M. Powell;Nathan Zilz;Yasmin Beazer-Barclay;Tracy M. Bryan

  • CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.

    Daniel J Weisenberger;Kimberly D Siegmund;Mihaela Campan;Joanne Young

  • Defective Mismatch Repair As a Predictive Marker for Lack of Efficacy of Fluorouracil-Based Adjuvant Therapy in Colon Cancer

    Daniel J. Sargent;Silvia Marsoni;Genevieve Monges;Stephen N. Thibodeau

  • Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E.

    Eric M. Reiman;Richard J. Caselli;Lang S. Yun;Kewei Chen

  • The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis.

    Charis Eng;Charis Eng;David Clayton;Isabelle Schuffenecker;Gilbert Lenoir

  • Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability

    Julie M. Cunningham;Eric R. Christensen;David J. Tester;Cheong Yong Kim

  • Characterization of human plasma-derived exosomal RNAs by deep sequencing

    Xiaoyi Huang;Tiezheng Yuan;Michael Tschannen;Zhifu Sun

  • Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals.

    Ronald C. Petersen;Glenn E. Smith;Robert J. Ivnik;Eric G. Tangalos

  • Actin mutations in dilated cardiomyopathy, a heritable form of heart failure

    Mark T. Keating;Thomas M. Olson

  • Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors

    Noralane M. Lindor;Lawrence J. Burgart;Olga Leontovich;Richard M. Goldberg

  • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Fredrick R. Schumacher;Ali Amin Al Olama;Sonja I. Berndt;Sara Benlloch

  • Colorectal cancer screening by detection of altered human DNA in stool: feasibility of a multitarget assay panel.

    David A. Ahlquist;Joel E. Skoletsky;Kevin A. Boynton;Jonathan J. Harrington

  • Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC.

    Lois M. Mulligan;Lois M. Mulligan;Charis Eng;Catherine S. Healey;David Clayton

  • Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1.

    Stephen N. Thibodeau;Amy J. French;Julie M. Cunningham;David Tester

  • Lower Cancer Incidence in Amsterdam-I Criteria Families Without Mismatch Repair Deficiency: Familial Colorectal Cancer Type X

    Noralane M. Lindor;Kari Rabe;Gloria M. Petersen;Robert Haile

  • Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling.

    Liu W;Dong X;Mai M;Seelan Rs

Frequent Co-Authors

Graham G. Giles
Graham G. Giles University of Melbourne
Daniel J. Schaid
Daniel J. Schaid Mayo Clinic
Polly A. Newcomb
Polly A. Newcomb Fred Hutchinson Cancer Research Center
John D. Potter
John D. Potter Massey University
John L. Hopper
John L. Hopper University of Melbourne
Janet L. Stanford
Janet L. Stanford Fred Hutchinson Cancer Research Center
Mark A. Jenkins
Mark A. Jenkins University of Melbourne
Robert W. Haile
Robert W. Haile Stanford University

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