D-Index & Metrics Best Publications
Stephen N. Thibodeau

Stephen N. Thibodeau

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 122 Citations 69,923 550 World Ranking 1911 National Ranking 1118

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Internal medicine

Stephen N. Thibodeau mainly investigates Internal medicine, Genetics, Cancer, Colorectal cancer and Pathology. His Internal medicine study incorporates themes from Gastroenterology, Surgery and Oncology. His work in Oncology addresses subjects such as Hazard ratio, which are connected to disciplines such as Adjuvant therapy and Survival analysis.

His Cancer study combines topics from a wide range of disciplines, such as Body mass index, Cancer research and Gene mutation. His research in Colorectal cancer intersects with topics in Cohort study, Microsatellite instability, Clinical trial and Adenocarcinoma. His work carried out in the field of Microsatellite instability brings together such families of science as Rectum, Carcinoma, DNA methylation and DNA mismatch repair.

His most cited work include:

  • Microsatellite instability in cancer of the proximal colon (2721 citations)
  • Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer (1652 citations)
  • APC mutations occur early during colorectal tumorigenesis. (1645 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Internal medicine, Oncology, Colorectal cancer, Genetics and Cancer. His studies in Internal medicine integrate themes in fields like Gastroenterology and Pathology. In his study, FOLFOX is strongly linked to Cetuximab, which falls under the umbrella field of Oncology.

His Colorectal cancer course of study focuses on Microsatellite instability and DNA mismatch repair and Carcinoma. Stephen N. Thibodeau has included themes like Mutation and Cancer research in his DNA mismatch repair study. His specific area of interest is Cancer, where Stephen N. Thibodeau studies Breast cancer.

He most often published in these fields:

  • Internal medicine (40.97%)
  • Oncology (32.20%)
  • Colorectal cancer (32.02%)

What were the highlights of his more recent work (between 2014-2021)?

  • Internal medicine (40.97%)
  • Oncology (32.20%)
  • Colorectal cancer (32.02%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Internal medicine, Oncology, Colorectal cancer, Prostate cancer and Cancer. In his research, Epidemiology is intimately related to Mendelian randomization, which falls under the overarching field of Internal medicine. His studies examine the connections between Oncology and genetics, as well as such issues in KRAS, with regards to FOLFOX.

His study explores the link between Colorectal cancer and topics such as Microsatellite instability that cross with problems in Carcinoma. His Prostate cancer research is multidisciplinary, incorporating elements of Genome-wide association study, Single-nucleotide polymorphism, Prostate, microRNA and Disease. His studies link Surgery with Cancer.

Between 2014 and 2021, his most popular works were:

  • REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants (546 citations)
  • Exosomal miR-1290 and miR-375 as Prognostic Markers in Castration-resistant Prostate Cancer (318 citations)
  • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (268 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Internal medicine

His primary scientific interests are in Internal medicine, Oncology, Genetics, Prostate cancer and Cancer. His work is connected to Colorectal cancer, Odds ratio and Aspirin, as a part of Internal medicine. Stephen N. Thibodeau has researched Colorectal cancer in several fields, including Proportional hazards model, Surgery, Microsatellite instability, Pathology and Adenocarcinoma.

His Oncology study integrates concerns from other disciplines, such as Monoallelic Mutation and Ovarian cancer. His Prostate cancer research incorporates themes from Genome-wide association study, Single-nucleotide polymorphism and Prostate. His Cancer research is multidisciplinary, incorporating perspectives in MUTYH and Family history.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Microsatellite instability in cancer of the proximal colon

S. N. Thibodeau;G. Bren;D. Schaid.
Science (1993)

4812 Citations

A National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer

C. Richard Boland;Stephen N. Thibodeau;Stanley R. Hamilton;David Sidransky.
Cancer Research (1998)

3815 Citations

Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

Christine M. Ribic;Daniel J. Sargent;Malcolm J. Moore;Malcolm J. Moore;Stephen N. Thibodeau.
The New England Journal of Medicine (2003)

2498 Citations

APC mutations occur early during colorectal tumorigenesis.

Steven M. Powell;Nathan Zilz;Yasmin Beazer-Barclay;Tracy M. Bryan.
Nature (1992)

2413 Citations

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.

Daniel J Weisenberger;Kimberly D Siegmund;Mihaela Campan;Joanne Young.
Nature Genetics (2006)

2080 Citations

Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E.

Eric M. Reiman;Richard J. Caselli;Lang S. Yun;Kewei Chen.
The New England Journal of Medicine (1996)

1549 Citations

Defective Mismatch Repair As a Predictive Marker for Lack of Efficacy of Fluorouracil-Based Adjuvant Therapy in Colon Cancer

Daniel J. Sargent;Silvia Marsoni;Genevieve Monges;Stephen N. Thibodeau.
Journal of Clinical Oncology (2010)

1524 Citations

The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis.

Charis Eng;Charis Eng;David Clayton;Isabelle Schuffenecker;Gilbert Lenoir.
JAMA (1996)

1363 Citations

Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability

Julie M. Cunningham;Eric R. Christensen;David J. Tester;Cheong Yong Kim.
Cancer Research (1998)

1209 Citations

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

Nilah M M. Ioannidis;Joseph H H. Rothstein;Joseph H H. Rothstein;Vikas Pejaver;Sumit Middha.
American Journal of Human Genetics (2016)

1050 Citations

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