World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
143
Citations
87969
World Ranking
1495
National Ranking
868

William B. Isaacs publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where William B. Isaacs sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 660 publications — 78th percentile

78% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

William B. Isaacs D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where William B. Isaacs sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 143 D-Index — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

William B. Isaacs is affiliated with Johns Hopkins University in the United States. Their research spans multiple domains within medicine, biochemistry, genetics, and molecular biology, with a particular concentration on prostate cancer treatment and research.

Their scholarly output includes significant contributions to prostate cancer diagnosis and treatment, as well as genetic associations and epidemiology. The scientist's work also touches on cancer genomics and diagnostics, cancer biology related to lipids and metabolism, cancer-related gene regulation, and genetic factors influencing colorectal cancer.

Isaacs has published extensively in notable venues, including:

  • UNC Libraries
  • The Prostate
  • European Urology
  • Journal of Clinical Oncology
  • European Urology Open Science

Frequent collaborators in their body of work include:

  • Jianfeng Xu
  • Kathleen A. Cooney
  • Brian T. Helfand
  • Elaine A. Ostrander
  • Zhuqing Shi

The following recent papers illustrate the scope and focus of Isaacs's research:

  • Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019 (2020), published in Journal of Clinical Oncology
  • Homologous recombination deficiency (HRD) score in germline BRCA2- versus ATM-altered prostate cancer (2021), published in Modern Pathology
  • Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors (2020), published in Oncogene
  • Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy (2020), published in Nature Communications
  • Rare Germline Variants in ATM Predispose to Prostate Cancer: A PRACTICAL Consortium Study (2021), published in European Urology Oncology

Their research topics fall within several subfields of medicine and biosciences, prominently including pulmonary and respiratory medicine, genetics, cancer research, molecular biology, and pathology and forensic medicine.

Overall, William B. Isaacs's body of work reflects research activity primarily focused on prostate cancer biology, genetics, diagnosis, and treatment, as well as related molecular mechanisms.

Best Publications

  • Overexpression of Hypoxia-inducible Factor 1α in Common Human Cancers and Their Metastases

    Hua Zhong;Angelo M. De Marzo;Erik Laughner;Michael Lim

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

    Nilah M M. Ioannidis;Joseph H H. Rothstein;Joseph H H. Rothstein;Vikas Pejaver;Sumit Middha

  • AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer.

    Emmanuel S. Antonarakis;Changxue Lu;Hao Wang;Brandon Luber

  • Inflammation in prostate carcinogenesis

    Angelo M. De Marzo;Angelo M. De Marzo;Elizabeth A. Platz;Siobhan Sutcliffe;Jianfeng Xu

  • Mutations of the VHL tumour suppressor gene in renal carcinoma

    J.R. Gnarra;K. Tory;Y. Weng;L. Schmidt

  • DD3::A New Prostate-specific Gene, Highly Overexpressed in Prostate Cancer

    M.J.G. Bussemakers;A. van Bokhoven;G.W.C.T. Verhaegh;F.P. Smit

  • The evolutionary history of lethal metastatic prostate cancer.

    Gunes Gundem;Peter Van Loo;Peter Van Loo;Peter Van Loo;Barbara Kremeyer;Ludmil B. Alexandrov

  • Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer

    Rong Hu;Thomas A. Dunn;Shuanzeng Wei;Sumit Isharwal

  • E-Cadherin Expression Is Silenced by DNA Hypermethylation in Human Breast and Prostate Carcinomas

    Jeremy R. Graff;James G. Herman;Rena G. Lapidus;Hemi Chopra

  • Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis

    Wen-Hsiang Lee;R. A. Morton;J. I. Epstein;J. D. Brooks

  • Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search

    Jeffrey R. Smith;Diha Freije;John D. Carpten;Henrik Grönberg;Henrik Grönberg

  • Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.

    Julius Gudmundsson;Patrick Sulem;Andrei Manolescu;Laufey T Amundadottir

  • Frequent Inactivation of PTEN/MMAC1 in Primary Prostate Cancer

    P Cairns;K Okami;S Halachmi;N Halachmi

  • DPC4 Gene in Various Tumor Types

    Mieke Schutte;Ralph H. Hruban;Lora Hedrick;Kathleen R. Cho

  • Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

    Young E. Whang;Xinyi Wu;Hiroyoshi Suzuki;Robert E. Reiter

  • Hereditary Prostate Cancer: Epidemiologic and Clinical Features

    Bob S. Carter;G. Steven Bova;Terri H. Beaty;Gary D. Steinberg

  • Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer.

    Umbas R;Schalken Ja;Aalders Tw;Carter Bs

  • Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

    P. Cairns;T. J. Polascik;Y. Eby;K. Tokino

  • The evolutionary history of lethal metastatic prostate cancer

    G Gundem;P Van Loo;B Kremeyer;L B Alexandrov

Frequent Co-Authors

Jianfeng Xu
Jianfeng Xu Arkansas State University
Patrick C. Walsh
Patrick C. Walsh Johns Hopkins University
Henrik Grönberg
Henrik Grönberg Karolinska Institute
Angelo M. De Marzo
Angelo M. De Marzo Johns Hopkins University School of Medicine
John D. Carpten
John D. Carpten University of Southern California
Fredrik Wiklund
Fredrik Wiklund Karolinska Institute
Elizabeth A. Platz
Elizabeth A. Platz Johns Hopkins University
William G. Nelson
William G. Nelson Johns Hopkins University School of Medicine
Janet L. Stanford
Janet L. Stanford Fred Hutchinson Cancer Research Center
Deborah A. Meyers
Deborah A. Meyers University of Arizona

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