D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 134 Citations 73,008 595 World Ranking 1188 National Ranking 701

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

Prostate cancer, Cancer research, Cancer, Prostate and Internal medicine are his primary areas of study. His research integrates issues of Single-nucleotide polymorphism and Pathology in his study of Prostate cancer. He has researched Cancer research in several fields, including DNA methylation, Carcinogenesis, Gene, Molecular biology and Chromoplexy.

His Cancer research is multidisciplinary, relying on both Genome-wide association study and PTEN. He usually deals with Prostate and limits it to topics linked to Risk factor and Epidemiology. His Internal medicine study combines topics in areas such as Endocrinology and Oncology.

His most cited work include:

  • Overexpression of Hypoxia-inducible Factor 1α in Common Human Cancers and Their Metastases (2003 citations)
  • AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer. (1567 citations)
  • Mutations of the VHL tumour suppressor gene in renal carcinoma (1437 citations)

What are the main themes of his work throughout his whole career to date?

William B. Isaacs mainly focuses on Prostate cancer, Internal medicine, Prostate, Oncology and Cancer research. He interconnects Single-nucleotide polymorphism, Genotype and Pathology in the investigation of issues within Prostate cancer. His Internal medicine research includes themes of Endocrinology and Gynecology.

As a member of one scientific family, William B. Isaacs mostly works in the field of Prostate, focusing on Tumor suppressor gene and, on occasion, Chromosome. His Oncology study combines topics from a wide range of disciplines, such as Prostatectomy, Germline mutation, Germline, Disease and Risk factor. His biological study spans a wide range of topics, including DNA methylation, Carcinogenesis, Gene, Chromoplexy and Androgen receptor.

He most often published in these fields:

  • Prostate cancer (72.80%)
  • Internal medicine (40.23%)
  • Prostate (34.53%)

What were the highlights of his more recent work (between 2015-2021)?

  • Prostate cancer (72.80%)
  • Internal medicine (40.23%)
  • Oncology (29.32%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Prostate cancer, Internal medicine, Oncology, Prostate and Cancer research. His Prostate cancer study deals with the bigger picture of Cancer. William B. Isaacs has researched Oncology in several fields, including Odds ratio, Prostatectomy, Disease and Genetic testing.

William B. Isaacs combines subjects such as Gastroenterology, Metastasis, Immunology and Pathology with his study of Prostate. His Cancer research research is multidisciplinary, incorporating elements of DNA methylation, Oncogene, Lymph node, Receptor and Androgen receptor. In his study, Genetic predisposition is inextricably linked to Gynecology, which falls within the broad field of Single-nucleotide polymorphism.

Between 2015 and 2021, his most popular works were:

  • REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants (546 citations)
  • Pan-cancer analysis of whole genomes (538 citations)
  • Germline Mutations in ATM and BRCA1/2 Distinguish Risk for Lethal and Indolent Prostate Cancer and are Associated with Early Age at Death. (140 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

William B. Isaacs mostly deals with Prostate cancer, Oncology, Internal medicine, Prostate and Cancer research. His Prostate cancer study introduces a deeper knowledge of Cancer. His work on Primary Gleason Pattern as part of general Cancer research is often related to MSH2, thus linking different fields of science.

His Oncology research is multidisciplinary, relying on both Germline mutation, Case-control study, Confidence interval, Proportional hazards model and Genetic testing. His Prostate research includes themes of Tumor microenvironment, Metastasis and Transplantation. His Cancer research research includes elements of Missense mutation, MiRNA binding, Microsatellite instability and Androgen receptor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Overexpression of Hypoxia-inducible Factor 1α in Common Human Cancers and Their Metastases

Hua Zhong;Angelo M. De Marzo;Erik Laughner;Michael Lim.
Cancer Research (1999)

3488 Citations

AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer.

Emmanuel S. Antonarakis;Changxue Lu;Hao Wang;Brandon Luber.
The New England Journal of Medicine (2014)

2402 Citations

Mutations of the VHL tumour suppressor gene in renal carcinoma

J.R. Gnarra;K. Tory;Y. Weng;L. Schmidt.
Nature Genetics (1994)

1969 Citations

Inflammation in prostate carcinogenesis

Angelo M. De Marzo;Angelo M. De Marzo;Elizabeth A. Platz;Siobhan Sutcliffe;Jianfeng Xu.
Nature Reviews Cancer (2007)

1904 Citations

DD3::A New Prostate-specific Gene, Highly Overexpressed in Prostate Cancer

M.J.G. Bussemakers;A. van Bokhoven;G.W.C.T. Verhaegh;F.P. Smit.
Cancer Research (1999)

1412 Citations

Pan-cancer analysis of whole genomes

Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart.
(2020)

1275 Citations

The evolutionary history of lethal metastatic prostate cancer.

Gunes Gundem;Peter Van Loo;Peter Van Loo;Peter Van Loo;Barbara Kremeyer;Ludmil B. Alexandrov.
Nature (2015)

1204 Citations

Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer

Rong Hu;Thomas A. Dunn;Shuanzeng Wei;Sumit Isharwal.
Cancer Research (2009)

1176 Citations

E-Cadherin Expression Is Silenced by DNA Hypermethylation in Human Breast and Prostate Carcinomas

Jeremy R. Graff;James G. Herman;Rena G. Lapidus;Hemi Chopra.
Cancer Research (1995)

1086 Citations

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

Nilah M M. Ioannidis;Joseph H H. Rothstein;Joseph H H. Rothstein;Vikas Pejaver;Sumit Middha.
American Journal of Human Genetics (2016)

1050 Citations

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National Institutes of Health

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